Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Anai M Perez"'
Autor:
Byoung Y Ryu, Kathryn R Michels, Alyssa Sheih, Susana A Hernandez, Alissa H Brandes, Don Parrilla, Blythe Irwin, Anai M Perez, Hung-An Ting, Christopher J Nicolai, Timothy Gervascio, Seungjin Shin, Mark D Pankau, Mason Muhonen, Jessica Freeman, Sarah Gould, Rich Getto, Ryan P Larson, Andrew M Scharenberg, Alessandra M Sullivan, Shon Green
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 3 (2023)
Background Chimeric antigen receptor (CAR) T-cell therapies have demonstrated transformational outcomes in the treatment of B-cell malignancies, but their widespread use is hindered by technical and logistical challenges associated with ex vivo cell
Externí odkaz:
https://doaj.org/article/a89752227f79448587a521f6cc52e072
Autor:
Stefan Radtke, Dnyanada Pande, Margaret Cui, Anai M. Perez, Yan-Yi Chan, Mark Enstrom, Stefanie Schmuck, Andrew Berger, Tom Eunson, Jennifer E. Adair, Hans-Peter Kiem
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 18, Iss , Pp 679-691 (2020)
Hematopoietic stem cell (HSC) gene therapy has the potential to cure many genetic, malignant, and infectious diseases. We have shown in a nonhuman primate gene therapy and transplantation model that the CD34+CD90+ cell fraction was exclusively respon
Externí odkaz:
https://doaj.org/article/261752fffa134004b8b8adfca84f2e43
Autor:
Stefan Radtke, PhD, Lucrezia Colonna, PhD, Anai M. Perez, BA, Michelle Hoffman, MS, Leslie S. Kean, MD, PhD, Hans-Peter Kiem, MD, PhD
Publikováno v:
Transplantation Direct, Vol 6, Iss 8, p e579 (2020)
Background. Allogeneic hematopoietic stem cell transplantation (allo-HCT) is a common treatment for patients suffering from different hematological disorders. Allo-HCT in combination with hematopoietic stem cell (HSC) gene therapy is considered a pro
Externí odkaz:
https://doaj.org/article/d3ed9cbd4f9f46bc83d3a9df3d70c639
Autor:
Rkia El-Kharrag, Kurt E. Berckmueller, Ravishankar Madhu, Margaret Cui, Gabriela Campoy, Heather M. Mack, Carl B. Wolf, Anai M. Perez, Olivier Humbert, Hans-Peter Kiem, Stefan Radtke
Publikováno v:
Mol Ther
Clinical applications of hematopoietic stem cell (HSC) gene editing are limited due to their complex and expensive logistics. HSC editing is commonly performed ex vivo using electroporation and requires good manufacturing practice (GMP) facilities, s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e005cc24577adbe147107518b4e2a261
https://doi.org/10.1016/j.ymthe.2022.02.026
https://doi.org/10.1016/j.ymthe.2022.02.026
Autor:
Kathryn R Michels, Alyssa Sheih, Susana A Hernandez, Alissa H Brandes, Don Parrilla, Blythe Irwin, Anai M Perez, Hung-An Ting, Christopher J Nicolai, Timothy Gervascio, Seungjin Shin, Mark D Pankau, Mason Muhonen, Jessica Freeman, Sarah Gould, Rich Getto, Ryan P Larson, Byoung Y Ryu, Andrew M Scharenberg, Alessandra M Sullivan, Shon Green
Publikováno v:
Journal for ImmunoTherapy of Cancer. 11:e006292
BackgroundChimeric antigen receptor (CAR) T-cell therapies have demonstrated transformational outcomes in the treatment of B-cell malignancies, but their widespread use is hindered by technical and logistical challenges associated with ex vivo cell m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c522fecb39d10b75cb27d68ee4c68604
https://doi.org/10.1136/jitc-2022-006292
https://doi.org/10.1136/jitc-2022-006292
Autor:
Stefan Radtke, Mark Enstrom, Dnyanada Pande, Ravishankar Madhu, Staci Owen, Greta Kanestrom, Margaret Cui, Anai M Perez, Hans-Peter Kiem
Publikováno v:
Blood. 140:5719-5720
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a07faaf8929f4f19ba15397400406a4d
https://doi.org/10.1182/blood-2022-158535
https://doi.org/10.1182/blood-2022-158535
Autor:
Margaret Cui, Andrew Berger, Stefanie Schmuck, Jennifer E. Adair, Anai M. Perez, Yan-Yi Chan, Tom Eunson, Hans-Peter Kiem, Stefan Radtke, Dnyanada Pande, Mark Enstrom
Publikováno v:
Molecular Therapy. Methods & Clinical Development
Molecular Therapy: Methods & Clinical Development, Vol 18, Iss, Pp 679-691 (2020)
Molecular Therapy: Methods & Clinical Development, Vol 18, Iss, Pp 679-691 (2020)
Hematopoietic stem cell (HSC) gene therapy has the potential to cure many genetic, malignant, and infectious diseases. We have shown in a nonhuman primate gene therapy and transplantation model that the CD34+CD90+ cell fraction was exclusively respon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::920b21f02a657c920794b84136a0fa70
http://europepmc.org/articles/PMC7424231
http://europepmc.org/articles/PMC7424231
Autor:
Mark Enstrom, Ravishankar Madhu, Stefan Radtke, Hans-Peter Kiem, Anai M. Perez, Margaret Cui, Dnyanada Pande
Reconstitution after hematopoietic stem cell (HSC) transplantation is assumed to occur in two distinct phases: initial recovery mediated by short-term progenitors and long-term repopulation by multipotent HSCs which do not contribute to hematopoietic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::962c6845b5571f8dc98cce5590d30e52
https://doi.org/10.1101/2021.09.21.461235
https://doi.org/10.1101/2021.09.21.461235
Autor:
Hans-Peter Kiem, Michelle Hoffman, Lucrezia Colonna, Anai M. Perez, Leslie S. Kean, Stefan Radtke
Publikováno v:
Transplantation Direct
Transplantation Direct, Vol 6, Iss 8, p e579 (2020)
Transplantation Direct, Vol 6, Iss 8, p e579 (2020)
Background. Allogeneic hematopoietic stem cell transplantation (allo-HCT) is a common treatment for patients suffering from different hematological disorders. Allo-HCT in combination with hematopoietic stem cell (HSC) gene therapy is considered a pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45b7b1f6ec7773e86a10056eb982b1d7
http://europepmc.org/articles/PMC7581184
http://europepmc.org/articles/PMC7581184
Publikováno v:
Acta Biomaterialia. 66:248-257
Cancer cell metastasis is responsible for approximately 90% of deaths related to cancer. The migration of cancer cells away from the primary tumor and into healthy tissue is driven in part by contact guidance, or directed migration in response to ali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e4bf39a985998057ce808e62e9fc92e
https://doi.org/10.1016/j.actbio.2017.11.039
https://doi.org/10.1016/j.actbio.2017.11.039