Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Anahita Shahraz"'
Autor:
Tawfik Abou Assale, Thomas Kuenzel, Tamara Schink, Anahita Shahraz, Harald Neumann, Christine Klaus
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Sialic acids are terminal sugars of the cellular glycocalyx and are highly abundant in the nervous tissue. Sialylation is sensed by the innate immune system and acts as an inhibitory immune checkpoint. Aminoglycoside antibiotics such as neomycin have
Externí odkaz:
https://doaj.org/article/5cd597601eca4746ad0e505fa58496ea
Autor:
Anahita Shahraz, Yuchen Lin, Joshua Mbroh, Jonas Winkler, Huan Liao, Marie Lackmann, Annemarie Bungartz, Peter F. Zipfel, Christine Skerka, Harald Neumann
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Sialic acids as the terminal caps of the cellular glycocalyx play an essential role in self-recognition and were shown to modulate complement processes via interaction between α2,3-linked sialic acids and complement factor H. Previously, it
Externí odkaz:
https://doaj.org/article/5e18edd0668c4872b5d67eae4e59fb39
Autor:
Marcus Karlstetter, Jens Kopatz, Alexander Aslanidis, Anahita Shahraz, Albert Caramoy, Bettina Linnartz‐Gerlach, Yuchen Lin, Anika Lückoff, Sascha Fauser, Katharina Düker, Janine Claude, Yiner Wang, Johannes Ackermann, Tobias Schmidt, Veit Hornung, Christine Skerka, Thomas Langmann, Harald Neumann
Publikováno v:
EMBO Molecular Medicine, Vol 9, Iss 2, Pp 154-166 (2016)
Abstract Age‐related macular degeneration (AMD) is a major cause of blindness in the elderly population. Its pathophysiology is linked to reactive oxygen species (ROS) and activation of the complement system. Sialic acid polymers prevent ROS produc
Externí odkaz:
https://doaj.org/article/c9673a88b97841d9b6dd28fb96463610
Autor:
Mona Mathews, Jannis Wißfeld, Lea Jessica Flitsch, Anahita Shahraz, Vesselina Semkova, Yannik Breitkreuz, Harald Neumann, Oliver Brüstle
Publikováno v:
Stem Cell Reviews and Reports. 19:455-474
Human microglia, as innate immune cells of the central nervous system (CNS), play a central role in the pathogenesis of a large number of neurological and psychiatric disorders. However, experimental access to primary human microglia for biomedical a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29b1b2b5fbba971c9ecc071ee71918a5
https://doi.org/10.1007/s12015-022-10433-w
https://doi.org/10.1007/s12015-022-10433-w
Publikováno v:
GliaREFERENCES. 69(12)
Parkinson's disease is one of the most common neurodegenerative diseases in the elderly population, with a pathophysiology linked to neuroinflammation, complement activation, and oxidative damage. Soluble polysialic acid with an average degree of pol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c17007f68c8b4eb4a103c5a861af91fa
https://pubmed.ncbi.nlm.nih.gov/34406679
https://pubmed.ncbi.nlm.nih.gov/34406679
Autor:
Anahita, Shahraz, Yuchen, Lin, Joshua, Mbroh, Jonas, Winkler, Huan, Liao, Marie, Lackmann, Annemarie, Bungartz, Peter F, Zipfel, Christine, Skerka, Harald, Neumann
Publikováno v:
Scientific reports. 12(1)
Sialic acids as the terminal caps of the cellular glycocalyx play an essential role in self-recognition and were shown to modulate complement processes via interaction between α2,3-linked sialic acids and complement factor H. Previously, it was sugg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::420e744594c4ba2c3a06efa6d7a368d2
https://pubmed.ncbi.nlm.nih.gov/35388026
https://pubmed.ncbi.nlm.nih.gov/35388026
Autor:
Albert Caramoy, Anahita Shahraz, Anika Lückoff, Yiner Wang, Harald Neumann, Johannes Ackermann, Yuchen Lin, Katharina Düker, Marcus Karlstetter, Jens Kopatz, Janine Claude, Sascha Fauser, Tobias Schmidt, Thomas Langmann, Bettina Linnartz-Gerlach, Alexander Aslanidis, Christine Skerka, Veit Hornung
Publikováno v:
EMBO Molecular Medicine
Age‐related macular degeneration (AMD) is a major cause of blindness in the elderly population. Its pathophysiology is linked to reactive oxygen species (ROS) and activation of the complement system. Sialic acid polymers prevent ROS production of h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::322e87d48b0c9ea54df125a0a68156d6
http://europepmc.org/articles/PMC5286381
http://europepmc.org/articles/PMC5286381
Autor:
Anahita Shahraz, Jens Kopatz, Dominic Winter, Vlad Schütza, Harald Neumann, Thomas Scheper, Shoba Kapoor, Joachim Kappler, Volkmar Gieselmann, Rene Mathy
Publikováno v:
Scientific Reports 5 (2015)
Scientific Reports
Scientific Reports
Oligosialic and polysialic acid (oligoSia and polySia) of the glycocalyx of neural and immune cells are linear chains, in which the sialic acid monomers are α2.8-glycosidically linked. Sialic acid-binding immunoglobulin-like lectin-11 (SIGLEC-11) is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c83888b9d97de38fb3fbfbeebb84dd1b
https://doi.org/10.1038/srep16800
https://doi.org/10.1038/srep16800
Autor:
Bettina, Linnartz-Gerlach, Christine, Schuy, Anahita, Shahraz, Andrea J, Tenner, Harald, Neumann
Publikováno v:
Glia. 64(1)
The complement system has been implicated in the removal of dysfunctional synapses and neurites during development and in disease processes in the mouse, but it is unclear how far the mouse data can be transferred to humans. Here, we co-cultured macr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::534afb0a0867a8043e3fe5bcc53bfcce
https://pubmed.ncbi.nlm.nih.gov/26257016
https://pubmed.ncbi.nlm.nih.gov/26257016
Autor:
Marzieh Mowlavi Vardanjani, Fatemeh Vahid Dastjerdi, Mahin Sadat Chavoshi, Masoud Soleimani, Amir Atashi, Anahita Shahraz, Irandokht Khaki Najafabadi, Bahman Zeynali, Azita Parvaneh Tafreshi
Publikováno v:
Cell biology international. 36(11)
GSK-3β is a key molecule in several signalling pathways, including the Wnt/β-catenin signalling pathway. There is increasing evidence suggesting Wnt/β-catenin signalling is involved in the neural differentiation of embryonic, somatic and neural st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6e9b7e54080395b733d61bd122929a8
https://pubmed.ncbi.nlm.nih.gov/22775567
https://pubmed.ncbi.nlm.nih.gov/22775567