Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Anahita Mojiri"'
Publikováno v:
Virology Journal, Vol 21, Iss 1, Pp 1-17 (2024)
Abstract Background Cell-penetrating peptides (CPPs) are effective for delivering therapeutic molecules with minimal toxicity. This study focuses on the use of penetratin, a well-characterized CPP, to deliver a DNA vector encoding short hairpin RNA (
Externí odkaz:
https://doaj.org/article/903d23d574e54d11bcf8ab6a1ae4c75d
Autor:
Lei Yuan, Gary C. Chan, David Beeler, Lauren Janes, Katherine C. Spokes, Harita Dharaneeswaran, Anahita Mojiri, William J. Adams, Tracey Sciuto, Guillermo Garcia-Cardeña, Grietje Molema, Peter M. Kang, Nadia Jahroudi, Philip A. Marsden, Ann Dvorak, Erzsébet Ravasz Regan, William C. Aird
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
Spontaneous phenotypic heterogeneity confers a population-level advantage to cells that are exposed to fluctuating environments. Here the authors show that the endothelium of some organs displays a dynamic mosaicism in expression of Von Willebrand fa
Externí odkaz:
https://doaj.org/article/6ed9333a2a8b469cb9f3182d7d55819d
Publikováno v:
European Heart Journal Open. 2
Aims Hutchinson–Gilford progeria syndrome (HGPS) is a pre-mature aging disorder caused by the mutation of the LMNA gene leading to an irreversibly farnesylated lamin A protein: progerin. The major causes of death in HGPS are coronary and arterial o
Autor:
Haniyeh Abuei, Mohammad Pirouzfar, Anahita Mojiri, Abbas Behzad-Behbahani, Tahereh Kalantari, Peyman Bemani, Ali Farhadi
Publikováno v:
Journal of microbiological methods. 200
p28 is a natural bacterial product, which recently has attracted much attention as an efficient cell penetrating peptide (CPP) and a promising anticancer agent. Considering the interesting biological qualities of p28, maximizing its expression appear
Publikováno v:
Circulation. 144
Hutchinson-Gilford progeria syndrome (HGPS) is a premature aging disorder caused by the mutation of LMNA gene leading to irreversibly farnesylated lamin A protein, i.e. progerin. The major causes of death in HGPS are coronary and arterial occlusive d
Autor:
Anahita Mojiri, Brandon Walther, Chongming Jiang, Gianfranco Matrone, Rhonda Holgate, Qiu Xu, Elisa Morales, Guangyu Wang, jianhua gu, Rongfu Wang, John P Cooke
Publikováno v:
Circulation. 144
Background: Hutchinson-Gilford Progeria Syndrome (HGPS) is an accelerated aging syndrome associated with premature vascular disease and death due to heart attack and stroke. In HGPS a mutation in lamin A (progerin), alters nuclear morphology and gene
Publikováno v:
Circulation. 144
Hutchinson-Gilford progeria syndrome (HGPS) is a model of accelerated vascular aging caused by a de novo mutation of a single nucleotide in the Lamin A gene. The accumulation of abnormal lamin A (progerin) in the nuclear envelope induces a nuclear dy
Autor:
Christian Boada, Brandon Walther, Rhonda Holgate, Elisa Morales, Xu Qiu, John P Cooke, Anahita Mojiri
Publikováno v:
Circulation. 144
Introduction: Hutchinson-Gilford Progeria Syndrome (HGPS) is an accelerated aging syndrome associated with premature vascular disease and death due to heart attack and stroke. In HGPS, a mutation in lamin A (progerin) alters nuclear morphology and ge
Autor:
Hosna Jabbari, Maryam Nakhaei-Nejad, Anahita Mojiri, Nadia Jahroudi, Allan G. Murray, Maikel Farhan
Publikováno v:
Stem Cells. 37:542-554
Endothelial cells play a central role in physiological function and pathophysiology of blood vessels in health and disease. However, the molecular mechanism that establishes the endothelial phenotype, and contributes to its signature cell type-specif
Autor:
Brandon K. Walther, Abhishek Jain, Jianhua Gu, Anthony Guiseppi-Elie, John P. Cooke, Roderic I. Pettigrew, Jacques Ohayon, Navaneeth Krishna Rajeeva Pandian, Anahita Mojiri, Huie Wang
Publikováno v:
Circulation. 142
Hutchinson-Gilford Progeria Syndrome (HGPS) is a disease of accelerated aging causing death in the mid-teens from myocardial infarction or stroke. The disease is caused by a point mutation in the gene encoding lamin-A. The mutated scaffolding protein