PDA Indolylmaleimides Induce Anti-Tumor Effects in Prostate Carcinoma Cell Lines Through Mitotic Death

Autor: Jan Torben Schille, Ingo Nolte, Julia Beck, Daria Jilani, Catrin Roolf, Anahit Pews-Davtyan, Arndt Rolfs, Larissa Henze, Matthias Beller, Bertram Brenig, Christian Junghanss, Ekkehard Schütz, Hugo Murua Escobar

Publikováno v: Frontiers in Veterinary Science, Vol 7 (2021)

Castrate resistant prostate cancer in men shares several characteristics with canine prostate cancer (PCa). Due to current insufficient therapies, evaluating novel therapeutic agents for late-stage PCa is of considerable interest for both species. PD

Externí odkaz: https://doaj.org/article/54cb6ffdb22744548f4214f34439892b

Synthesis of Pharmacologically Relevant New Derivatives of Maleimides via Ligand-Free Pd-Catalyzed Suzuki–Miyaura Cross-Coupling Reactions

Autor: Anahit Pews-Davtyan, Ralf Jackstell, Muhammad Sharif, Matthias Beller, Julita Opalach

Publikováno v: Arabian Journal for Science and Engineering. 45:4717-4725

The Suzuki–Miyaura coupling reactions were applied for synthesis of pharmacological relevant derivatives of known 3,4-dibromo-1-methyl-1H-pyrrole-2,5-dione compound. Suzuki–Miyaura reactions of 3,4-dibromo-1-methyl-1H-pyrrole-2,5-dione with two e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::78bfb0793f45e42f2339a11162c9e9ba
https://doi.org/10.1007/s13369-020-04450-5

Biomolecule-derived supported cobalt nanoparticles for hydrogenation of industrial olefins, natural oils and more in water

Autor: Carsten Kreyenschulte, Maximilian Franz Hertrich, Ralf Jackstell, Henrik Lund, Matthias Beller, Stephan Bartling, Anahit Pews-Davtyan, Florian Korbinian Scharnagl

Publikováno v: Green Chemistry. 21:5104-5112

Catalytic hydrogenation of olefins using noble metal catalysts or pyrophoric RANEY® nickel is of high importance in the chemical industry. From the point of view of green and sustainable chemistry, design and development of Earth-abundant, less toxi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::74c7fd75ca7a045cace66ae55a6d4d06
https://doi.org/10.1039/c9gc01276a

Assessment of the efficacy of targeted PDA-66 therapy in a PC-3 Prostate Cancer Xenograft Model using [ 18 F]FDG and [ 18 F]FLT PET/CT and MRI

Autor: R Schwarz, S Sender, Brigitte Vollmar, Anahit Pews-Davtyan, BJ Krause, SM Schwarzenböck, Hugo Murua Escobar, C Junghanß, M Guliyev, A Moeller, A Velicu, C Schlie, M Joksch, D Zechner, Matthias Beller, Tobias Lindner, Jan Stenzel, B Hinz, C Bergner, J Förster

Publikováno v: 58. Jahrestagung der Deutschen Gesellschaft für Nuklearmedizin.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::468e67ee25d9e12782770c428db877fb
https://doi.org/10.1055/s-0040-1708319

Ambroxol and bromhexine derivatives as pharmacological chaperones for mutant glucocerebrosidase

Autor: Matthias Beller, Maria Vittoria Cubellis, Hila Braunstein, Elisabeth Mieske, Susanne Seemann, Giuseppina Andreotti, Arndt Rolfs, Chiara Cimmaruta, Muhammad Sharif, Jan Lukas, Chaonan Zheng, Anahit Pews-Davtyan, Mia Horowitz

Publikováno v: Molecular genetics and metabolism
120 (2017): S87–S87. doi:10.1016/j.ymgme.2016.11.213
info:cnr-pdr/source/autori:Lukas, Jan; Seemann, Susanne; Sharif, Muhammad; Zheng, Chaonan; Cimmaruta, Chiara; Braunstein, Hila; Pews-Davtyan, Anahit; Mieske, Elisabeth; Andreotti, Giuseppina; Cubellis, Maria V.; Beller, Matthias; Horowitz, Mia; Rolfs, Arndt/titolo:Ambroxol and bromhexine derivatives as pharmacological chaperones for mutant glucocerebrosidase/doi:10.1016%2Fj.ymgme.2016.11.213/rivista:Molecular genetics and metabolism (Print)/anno:2017/pagina_da:S87/pagina_a:S87/intervallo_pagine:S87–S87/volume:120

Gaucher disease (GD) is a rare, autosomal recessive metabolic disorder of glycosphingolipid storage and is caused by mutations in the gene encoding the lysosomal hydrolase glucocerebrosidase (GCase). Certain genotypes do not lead to a complete loss-o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a2022ad86704017d3a936e09b24d370