Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Anabelle, Decottignies"'
Autor:
Nuria Suelves, Shirine Saleki, Tasha Ibrahim, Debora Palomares, Sebastiaan Moonen, Marta J. Koper, Céline Vrancx, Devkee M. Vadukul, Nicolas Papadopoulos, Nikenza Viceconte, Eloïse Claude, Rik Vandenberghe, Christine A. F. von Arnim, Stefan N. Constantinescu, Dietmar Rudolf Thal, Anabelle Decottignies, Pascal Kienlen-Campard
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-26 (2023)
Abstract Aging is the main risk factor for Alzheimer’s disease (AD) and other neurodegenerative pathologies, but the molecular and cellular changes underlying pathological aging of the nervous system are poorly understood. AD pathology seems to cor
Externí odkaz:
https://doaj.org/article/5f4fdaf58fee4378a6e15e3c44d2238d
Autor:
Eloïse Claude, Guillaume de Lhoneux, Christophe E. Pierreux, Etienne Marbaix, Maëlle de Ville de Goyet, Cécile Boulanger, An Van Damme, Bénédicte Brichard, Anabelle Decottignies
Publikováno v:
Molecular Biomedicine, Vol 2, Iss 1, Pp 1-16 (2021)
Abstract The vast majority of adult cancer cells achieve cellular immortality by activating a telomere maintenance mechanism (TMM). While this is mostly achieved by the de-silencing of hTERT telomerase gene expression, an alternative homologous recom
Externí odkaz:
https://doaj.org/article/02307fbeea694d559dabdfc3471879e2
Autor:
Gladys, Battisti, René, Wintjens, Anabelle, Decottignies, Ahmad, Merhi, Caroline, Fervaille, Etienne, Sokal, Deniz, Karadurmus, Valerie, Benoit, Anick, Claessens, Jean-Paul, Martinet, Benoît, Martiat, Philippe, Kinzinger, Isabelle, Maystadt
Publikováno v:
In European Journal of Medical Genetics December 2021 64(12)
Publikováno v:
Bone Reports, Vol 13, Iss , Pp 100367- (2020)
Externí odkaz:
https://doaj.org/article/2e462912c6b348ba85cf2fc97517a1c8
Publikováno v:
Molecular & Cellular Oncology, Vol 6, Iss 6 (2019)
Some tumors acquire replicative immortality by activating an ALTernative telomerase-independent telomere maintenance mechanism. ALT offers interesting therapeutic perspectives but lacks any known specific targets. We discovered a crucial role for TSP
Externí odkaz:
https://doaj.org/article/cf64ff5242be4fffb8ab7e690dd7e524
Autor:
Nikenza Viceconte, Marie-Sophie Dheur, Eva Majerova, Christophe E. Pierreux, Jean-François Baurain, Nicolas van Baren, Anabelle Decottignies
Publikováno v:
Cell Reports, Vol 19, Iss 12, Pp 2529-2543 (2017)
Summary: Unlimited replicative potential is one of the hallmarks of cancer cells. In melanoma, hTERT (telomerase reverse transcriptase) is frequently overexpressed because of activating mutations in its promoter, suggesting that telomerase is necessa
Externí odkaz:
https://doaj.org/article/5cd459471a4d4d31bf46f48e839eb5df
Autor:
Maname Benyelles, Harikleia Episkopou, Marie‐Françoise O'Donohue, Laëtitia Kermasson, Pierre Frange, Florian Poulain, Fatma Burcu Belen, Meltem Polat, Christine Bole‐Feysot, Francina Langa‐Vives, Pierre‐Emmanuel Gleizes, Jean‐Pierre deVillartay, Isabelle Callebaut, Anabelle Decottignies, Patrick Revy
Publikováno v:
EMBO Molecular Medicine, Vol 11, Iss 7, Pp n/a-n/a (2019)
Abstract PARN, poly(A)‐specific ribonuclease, regulates the turnover of mRNAs and the maturation and stabilization of the hTR RNA component of telomerase. Biallelic PARN mutations were associated with Høyeraal–Hreidarsson (HH) syndrome, a rare t
Externí odkaz:
https://doaj.org/article/6b17fc6a05d04cf4a3910e137cab5d9f
Autor:
Nuria Suelves, Shirine Saleki, Tasha Ibrahim, Debora Palomares, Céline Vrancx, Devkee M Vadukul, Nicolas Papadopoulos, Nikenza Viceconte, Eloïse Claude, Stefan N. Constantinescu, Anabelle Decottignies, Pascal Kienlen-Campard
Aging is a well-known risk factor for Alzheimer’s disease (AD) and other neurodegenerative pathologies, but the molecular and cellular changes occurring in the aging brain are poorly understood. AD pathology seems to correlate with the appearance o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79ff8589769b060a854fbf599767505a
https://doi.org/10.1101/2022.10.17.512098
https://doi.org/10.1101/2022.10.17.512098
Publikováno v:
Nutrients, Vol 10, Iss 12, p 1942 (2018)
As the world demographic structure is getting older, highlighting strategies to counteract age-related diseases is a major public health concern. Telomeres are nucleoprotein structures that serve as guardians of genome stability by ensuring protectio
Externí odkaz:
https://doaj.org/article/eb1feaf09c5d4eef9463a833b1274909
Autor:
Pierre-François Laterre, Benoît Ghaye, Jean Cyr Yombi, Antoine Froidure, Manon Mahieu, Anabelle Decottignies, Jean-Philippe Defour, Delphine Hoton, Sandra Koenig
Publikováno v:
Aging (Albany NY)
Aging, Vol. 12, no. 20, p. 19911-19922 (2020)
Aging, Vol. 12, no. 20, p. 19911-19922 (2020)
Telomeres are non-coding DNA sequences that protect chromosome ends and shorten with age. Short telomere length (TL) is associated with chronic diseases and immunosenescence. The main risk factor for mortality of coronavirus disease 2019 (COVID-19) i