Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Anabel Varela"'
Autor:
Lucy Penfold, Angela Woods, Alice E. Pollard, Julia Arizanova, Eneko Pascual-Navarro, Phillip J. Muckett, Marian H. Dore, Alex Montoya, Chad Whilding, Louise Fets, Joao Mokochinski, Theodora A. Constantin, Anabel Varela-Carver, Damien A. Leach, Charlotte L. Bevan, Alexander Yu. Nikitin, Zoe Hall, David Carling
Publikováno v:
Cell Reports, Vol 42, Iss 4, Pp 112396- (2023)
Summary: Emerging evidence indicates that metabolic dysregulation drives prostate cancer (PCa) progression and metastasis. AMP-activated protein kinase (AMPK) is a master regulator of metabolism, although its role in PCa remains unclear. Here, we sho
Externí odkaz:
https://doaj.org/article/11a6b824917b48fc8d5c5b5a9e0faa99
Autor:
Theodora A. Constantin, Anabel Varela-Carver, Kyle K. Greenland, Gilberto Serrano de Almeida, Ellen Olden, Lucy Penfold, Simon Ang, Alice Ormrod, Damien A. Leach, Chun-Fui Lai, Edward K. Ainscow, Ash K. Bahl, David Carling, Matthew J. Fuchter, Simak Ali, Charlotte L. Bevan
Background Current strategies to inhibit androgen receptor (AR) are circumvented in castration-resistant prostate cancer (CRPC). Cyclin-dependent kinase 7 (CDK7) promotes AR signalling, in addition to established roles in cell cycle and global transc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eca8b4b5eb80fb0db7513376e511998
http://hdl.handle.net/10044/1/103960
http://hdl.handle.net/10044/1/103960
Autor:
Anabel Varela-Carver, Ines Figueiredo, Yang Liu, Folake Orafidiya, Ian G. Mills, Joanna Hester, Bono Johann de, Oliwia Cyran, Richard J. Bryant, Charlotte L. Bevan, Wei Yuan, Karen E. Knudsen, Hiromi Kudo, Shuang G Zhao, Robert G. Bristow, Lin Deng, Antje Neeb, Eileen Parkes, Bora Gurel, Felix Y. Feng, Yiannis Philippou, Theodora Constantin, Fadi Issa, Denisa Bogdan, Marc Lorentzen, Ronnie Rodrigues Pereira, Simon H. Reed, Felix Dobbs, Claire E. Fletcher
Publikováno v:
Endocrine Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c981f152b08fb16bb2e16223f4374cd7
https://doi.org/10.1530/endoabs.77.oc2.5
https://doi.org/10.1530/endoabs.77.oc2.5
Autor:
Serena Tommasini Ghelfi, Charlotte L. Bevan, Alwyn Dart, Anabel Varela-Carver, Alysha Bhatti, Almeida Gilberto Serrano de
Publikováno v:
Endocrine Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5210bda0a85392b4afc9c0fb655b382
https://doi.org/10.1530/endoabs.42.oc15
https://doi.org/10.1530/endoabs.42.oc15
Autor:
Sergio Ghione, Enza Fommei, Giulia d'Amati, L. Donato, Paolo G. Camici, Massimiliano Mancini, Patrizia Pisani, Massimo Lombardi, Danilo Neglia, Anabel Varela-Carver, Howard Parker
Publikováno v:
Journal of Hypertension. 29:364-372
Patients and animal models of arterial hypertension are characterized by structural and functional abnormalities of the coronary microcirculation. Using a translational approach, we ascertained whether antihypertensive treatment can reverse microvasc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a08ea5c4b00181b2af7f5e2eaf7c7690
https://doi.org/10.1097/hjh.0b013e328340a08e
https://doi.org/10.1097/hjh.0b013e328340a08e
Autor:
Anthony Rosenzweig, Nicola H. Strickland, Paolo G. Camici, Takashi Matsui, Saumya Das, Anabel Varela-Carver, Christina Kleinert, Stuart A. Cook, Muhammad Tahir Khan, Lucia Leccisotti, Marco Mongillo, Prakash P Punjabi
Publikováno v:
European Heart Journal. 31:100-111
Aims Whole body and myocardial insulin resistance are features of non-insulin-dependent diabetes mellitus (NIDDM) and left-ventricular dysfunction (LVD). We determined whether abnormalities of insulin receptor substrate-1 (IRS1), IRS1-associated PI3K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4741c91d2b60d9ad0e0157bdbd13117
https://doi.org/10.1093/eurheartj/ehp396
https://doi.org/10.1093/eurheartj/ehp396
Donor cell-type specific paracrine effects of cell transplantation for post-infarction heart failure
Autor:
Scott Brouilette, Ken Suzuki, Anabel Varela-Carver, Satsuki Fukushima, Steven R. Coppen, Cesare M. Terracciano, Yasunori Shintani, Joon Ha Lee, Magdi H. Yacoub, Kunihiko Takahashi, Kenta Yashiro
Publikováno v:
Journal of Molecular and Cellular Cardiology. 47:288-295
Cell transplantation is an emerging therapy for treating post-infarction heart failure. Although the paracrine effect has been proposed to be an important mechanism for the therapeutic benefits, details remain largely unknown. This study compared var
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f9170f9b0df4204724590449152ea22
https://doi.org/10.1016/j.yjmcc.2009.05.009
https://doi.org/10.1016/j.yjmcc.2009.05.009
Autor:
Anabel Varela-Carver, Steven R. Coppen, Ken Suzuki, Paul J.R. Barton, Leanne E. Felkin, Satsuki Fukushima, Kenichi Yamahara, Magdi H. Yacoub
Publikováno v:
Biochemical and Biophysical Research Communications. 371:615-620
Side population cells have been found in various types of adult tissue including heart and are presumed to be tissue-specific stem/progenitor cells. In the present study, we confirmed the presence of cardiac side population (cSP) cells, which showed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d66a173ebe1143aa22bbde5f9542d197
https://doi.org/10.1016/j.bbrc.2008.04.021
https://doi.org/10.1016/j.bbrc.2008.04.021
Autor:
Anabel Varela-Carver, Nigel J. Brand, Ken Suzuki, Bari Murtuza, Satsuki Fukushima, Magdi H. Yacoub
Publikováno v:
Journal of Molecular and Cellular Cardiology. 36:603-606
One of the major issues in myocardial gene therapy is poor transfection efficiency. The herpes simplex virus protein VP22 is known to facilitate intercellular protein transport. Not only VP22 but also VP22-linked protein are exported from the cytopla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8cb6c254293d654aaafb8f837cff513
https://doi.org/10.1016/j.yjmcc.2004.01.007
https://doi.org/10.1016/j.yjmcc.2004.01.007