DNA delivery and genomic integration into mammalian target cells through Type IV A and B secretion systems of human pathogens

Autor: Matxalen Llosa, Dolores L. Guzmán-Herrador, Coral González-Prieto, Samuel Steiner, Anabel Alperi, Craig R. Roy

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
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Frontiers in Microbiology August 2017 Volume 8 Article 1503
UCrea Repositorio Abierto de la Universidad de Cantabria
Universidad de Cantabria (UC)
Frontiers in Microbiology
Frontiers in Microbiology, Vol 8 (2017)

We explore the potential of bacterial secretion systems as tools for genomic modification of human cells. We previously showed that foreign DNA can be introduced into human cells through the Type IV A secretion system of the human pathogen Bartonella

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2115316f2e82914012c8bfb93518f912
http://hdl.handle.net/10261/164663

Human isolates of Aeromonas possess Shiga toxin genes (stx1 and stx2) highly similar to the most virulent gene variants of Escherichia coli

Autor: Anabel Alperi, Maria José Figueras

Publikováno v: Clinical Microbiology and Infection. 16:1563-1567

Strains producing Shiga toxins, encoded by stx1 and stx2 genes, can cause diarrhoea, haemorrhagic colitis and haemolytic uremic syndrome. PCR screening of 80 clinical Aeromonas strains showed that 19 were stx1-positive and only one was positive for b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00eb6b8fea2647553dd4371c73efb0df
https://doi.org/10.1111/j.1469-0691.2010.03203.x

Phylogenetic Evidence Suggests That Strains of Aeromonas hydrophila subsp. dhakensis Belong to the Species Aeromonas aquariorum sp. nov

Autor: Anabel Alperi, Maria-Jose Figueras, Arturo Monera, Antonio J. Martínez-Murcia, Maria-José Saavedra

Publikováno v: Current Microbiology. 58:76-80

Three strains of Aeromonas hydrophila subspecies dhakensis, including the type strain, were subjected to phylogenetic analysis by sequencing gyrB, rpoD, and 16S rRNA genes and compared with all known Aeromonas species. The obtained gyrB and rpoD phyl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d6286f700c0a9aa366b995328022f7a
https://doi.org/10.1007/s00284-008-9278-6

Aeromonas rivuli sp. nov., isolated from the upstream region of a karst water rivulet

Autor: Maria José Figueras, Arturo Monera, Antonio J. Martínez-Murcia, Evelyne Brambilla, Anabel Alperi, Erko Stackebrandt, Roxana Beaz-Hidalgo

Publikováno v: International journal of systematic and evolutionary microbiology. 61(Pt 2)

Two freshwater isolates (WB4.1-19T and WB4.4-101), sharing 99.9 % 16S rRNA gene sequence similarity, were highly related to Aeromonas sobria (99.7 % similarity; 6 bp differences). A phylogenetic tree derived from a multi-locus phylogenetic analysis (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a974ab339c4d198c7d2463656c3474ec
https://pubmed.ncbi.nlm.nih.gov/20207806

Comparison of phenotypical and genetic identification of Aeromonas strains isolated from diseased fish

Autor: Jesús L. Romalde, Roxana Beaz-Hidalgo, Anabel Alperi, Noemí Buján, Maria José Figueras

Publikováno v: Systematic and applied microbiology. 33(3)

Phenotypicaly identified Aeromonas strains (n=119) recovered mainly from diseased fish were genetically re-identified and the concordance between the results was analysed. Molecular characterization based on the GCAT genus specific gene showed that o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e6684a9fb2746d2f1290d0f2eb9fb04
https://pubmed.ncbi.nlm.nih.gov/20227844