Notch3 regulates Mybl2 via HeyL to limit proliferation and tumor initiation in breast cancer

Autor: Sonia Brahim, Ana-Maria Negulescu, Clara Geneste, Thomas Schott, Shuheng Lin, Louis-Oscar Morel, Nicolas Rama, Nicolas Gadot, Isabelle Treilleux, Patrick Mehlen, Olivier Meurette

Publikováno v: Cell Death and Disease, Vol 14, Iss 2, Pp 1-11 (2023)

Abstract Notch signaling is a conserved signaling pathway that participates in many aspects of mammary gland development and homeostasis, and has extensively been associated with breast tumorigenesis. Here, to unravel the as yet debated role of Notch

Externí odkaz: https://doaj.org/article/0078f36b37f9467e9f5dc9a7413d85b2

Regulation by miR181 Family of the Dependence Receptor CDON Tumor Suppressive Activity in Neuroblastoma

Autor: Frantz Bouhallier, Fabrice Lavial, Céline Delloye-Bourgeois, Joanna Fombonne, Patrick Mehlen, Ana Maria Negulescu, Olivier Meurette, Marion Creveaux, Benjamin Gibert, Solen Le Guernevel, Benjamin Ducarouge, Olivier Delattre, Jean Bénard, Charles-Henry Gattolliat, Annick Harel-Bellan, Isabelle Janoueix-Lerosey

Publikováno v: JNCI: Journal of the National Cancer Institute
JNCI: Journal of the National Cancer Institute, Oxford University Press (OUP), 2014, 106 (11), ⟨10.1093/jnci/dju318⟩
JNCI: Journal of the National Cancer Institute, 2014, 106 (11), ⟨10.1093/jnci/dju318⟩

BACKGROUND The Sonic Hedgehog (SHH) signaling pathway plays an important role in neural crest cell fate during embryonic development and has been implicated in the progression of multiple cancers that include neuroblastoma, a neural crest cell-derive

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58613cfc3296760fc76b26f74fd2f4d0
https://hal.archives-ouvertes.fr/hal-02463304