Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Ana-Maria Lennon Dumenil"'
Autor:
Anita Kumari, Judith Pineau, Pablo J. Sáez, Mathieu Maurin, Danielle Lankar, Mabel San Roman, Katharina Hennig, Vanessa F. Boura, Raphael Voituriez, Mikael C. I. Karlsson, Martial Balland, Ana-Maria Lennon Dumenil, Paolo Pierobon
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
The immune synapse promotes cellular information exchange but the role of biophysical forces in synapse function is unclear. Here, the authors show that B cells exert two types of forces, a centripetal myosin II-driven force and a central actin protr
Externí odkaz:
https://doaj.org/article/153dc305ef9a4480872d0c78f10b8923
Autor:
Yessia Hidalgo, Sarah Núñez, Maria Jose Fuenzalida, Felipe Flores-Santibáñez, Pablo J. Sáez, Jessica Dorner, Ana-Maria Lennon-Dumenil, Victor Martínez, Emmanuel Zorn, Mario Rosemblatt, Daniela Sauma, Maria Rosa Bono
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the activation of autoreactive T and B cells, autoantibody production, and immune complex deposition in various organs. Previous evidence showed abnormal accumulation of B c
Externí odkaz:
https://doaj.org/article/0f41c6a3db1d40fbab671f264b1a1c4a
Innate Immune Signals Induce Anterograde Endosome Transport Promoting MHC Class I Cross-Presentation
Autor:
Mirjana Weimershaus, François-Xavier Mauvais, Loredana Saveanu, Cézaire Adiko, Joël Babdor, Anastasia Abramova, Sebastian Montealegre, Myriam Lawand, Irini Evnouchidou, Katharina Julia Huber, Alexandra Chadt, Markus Zwick, Pablo Vargas, Michael Dussiot, Ana Maria Lennon-Dumenil, Thomas Brocker, Hadi Al-Hasani, Peter van Endert
Publikováno v:
Cell Reports, Vol 24, Iss 13, Pp 3568-3581 (2018)
Summary: Both cross-presentation of antigens by dendritic cells, a key pathway triggering T cell immunity and immune tolerance, and survival of several pathogens residing in intracellular vacuoles are intimately linked to delayed maturation of vesicl
Externí odkaz:
https://doaj.org/article/03d579d8d66a4ee7b4950ef891d556c1
Autor:
Elisa Bonnin, Jordan Denizeau, Mathieu Maurin, Juan Jose Saez, Mabel Jouve, Pierre-Emmanuel Bonté, Wilfrid Richer, Fabien Nevo, Sebastien Lemoine, Nicolas Girard, Marine Lefevre, Edith Borcoman, Anne Vincent-Salomon, Sylvain Baulande, Hélène Moreau, Christine Sedlik, Claire Hivroz, Ana-Maria Lennon-Dumenil, Jimena Tosello Boari, Eliane Piaggio
Regulatory T cells (Tregs) are plastic cells playing a pivotal role in the maintenance of immune homeostasis. Tregs actively adapt to the microenvironment where they reside; as a consequence, their molecular and functional profiles differ among tissu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1bb595dfa668e1cf5cdc7f147868d218
https://doi.org/10.21203/rs.3.rs-2747594/v1
https://doi.org/10.21203/rs.3.rs-2747594/v1
Publikováno v:
Comptes Rendus. Biologies. 344:337-356
The colon is primarily responsible for absorbing fluids. It contains a large number of microorganisms including fungi, which are enriched in its distal segment. The colonic mucosa must therefore tightly regulate fluid influx to control absorption of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24b9c1f9c001437903eaf5108b84aabb
https://doi.org/10.5802/crbiol.67
https://doi.org/10.5802/crbiol.67
Autor:
Cesar Oyarce, Sebastián Cruz-Gomez, Felipe Galvez-Cancino, Pablo Vargas, Hélène D. Moreau, Natalia Diaz-Valdivia, Jorge Diaz, Flavio Andres Salazar-Onfray, Rodrigo Pacheco, Ana Maria Lennon-Dumenil, Andrew F. G. Quest, Alvaro Lladser
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Dendritic cell (DC) trafficking from peripheral tissues to lymph nodes (LNs) is a key step required to initiate T cell responses against pathogens as well as tumors. In this context, cellular membrane protrusions and the actin cytoskeleton are essent
Externí odkaz:
https://doaj.org/article/975fb8be8c604d48ab5f793da7273674
Autor:
Remy Char, Zhuangzhuang Liu, Marion Davieau, Cedric Jacqueline, Maria-Graciela Delgado, Raphael Chapuy, Mathieu Fallet, Lionel Chasson, Voahirana Camosseto, Eva Strock, Rejane Rua, Catarina Almeida, Bing Su, Ana-Maria Lennon-Dumenil, Antoine Roquilly, Yinming Liang, Stéphane Méresse, Evelina Gatti, philippe pierre
Endo-lysosomes transport along microtubules and clustering in the perinuclear area are two necessary steps for microbes to activate specialized phagocyte functions. We report that RUN and FYVE domain-containing protein 3 exists as two alternative iso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e46d536c680472d0ae7a4612eca29d9b
https://doi.org/10.21203/rs.3.rs-2120902/v1
https://doi.org/10.21203/rs.3.rs-2120902/v1
Autor:
Sara V. Merino-Cortes, Paolo Pierobon, Ana-Maria Lennon Dumenil, Yolanda R. Carrasco, Ana Martínez-Riaño, Sara Roman-Garcia, Rosa Liébana, Julien Husson, Sofia R. Gardeta, Balbino Alarcón, Judith Pineau, Isabel Mérida
Publikováno v:
Science Signaling
Science Signaling, American Association for the Advancement of Science, 2020, 13 (627), pp.eaaw8214. ⟨10.1126/scisignal.aaw8214⟩
Science Signaling, 2020, 13 (627), pp.eaaw8214. ⟨10.1126/scisignal.aaw8214⟩
Digital.CSIC. Repositorio Institucional del CSIC
instname
Science Signaling, American Association for the Advancement of Science, 2020, 13 (627), pp.eaaw8214. ⟨10.1126/scisignal.aaw8214⟩
Science Signaling, 2020, 13 (627), pp.eaaw8214. ⟨10.1126/scisignal.aaw8214⟩
Digital.CSIC. Repositorio Institucional del CSIC
instname
Diacylglycerol kinases (DGKs) limit antigen receptor signaling in immune cells by consuming the second messenger diacylglycerol (DAG) to generate phosphatidic acid (PA). Here, we showed that DGKζ promotes lymphocyte function–associated antigen 1 (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd7cebb4fe04a03595e584fd2a7c4827
http://hdl.handle.net/10261/228928
http://hdl.handle.net/10261/228928
Autor:
Benny Hung-Junn Chang, Grégoire Lauvau, Pierre Guermonprez, Stéphanie Hugues, Julie Helft, Ana Maria Lennon Dumenil, Michel C. Nussenzweig, Pradeep Kumar, Sebastian Amigorena, Pablo Vargas, Lawrence Chan, Sangeeta Tiwari, Laurence Bougnères, Laura Campisi, John D. MacMicking, Alice O. Kamphorst
Publikováno v:
Immunity, Vol. 31, No 2 (2009) pp. 232-244
Dendritic cells (DCs) have the striking ability to cross-present exogenous antigens in association with major histocompatibility complex (MHC) class I to CD8(+) T cells. However, the intracellular pathways underlying cross-presentation remain ill def
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e6ce9626d6dbad093d1da72c11575eb
Autor:
Judith Pineau, Léa Pinon, Olivier Mesdjian, Jacques Fattaccioli, Ana-Maria Lennon Duménil, Paolo Pierobon
Publikováno v:
eLife, Vol 11 (2022)
Immune synapse formation is a key step for lymphocyte activation. In B lymphocytes, the immune synapse controls the production of high-affinity antibodies, thereby defining the efficiency of humoral immune responses. While the key roles played by bot
Externí odkaz:
https://doaj.org/article/8567b4f1384a47ec8f801b546e5ad540