Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Ana-Maria Dragoi"'
Autor:
Ascención Torres-Escobar, Ashley Wilkins, María D. Juárez-Rodríguez, Magdalena Circu, Brian Latimer, Ana-Maria Dragoi, Stanimir S. Ivanov
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract The accidental human pathogen Legionella pneumophila (Lp) is the etiological agent for a severe atypical pneumonia known as Legionnaires’ disease. In human infections and animal models of disease alveolar macrophages are the primary cellul
Externí odkaz:
https://doaj.org/article/4425f9fbfb6c4b7faf351a32a50236d8
Autor:
Nilu Dhungel, Ana-Maria Dragoi
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
The interaction between the tumor microenvironment (TME) and the cancer cells is a complex and mutually beneficial system that leads to rapid cancer cells proliferation, metastasis, and resistance to therapy. It is now recognized that cancer cells ar
Externí odkaz:
https://doaj.org/article/8d723fd269804b3aae7ccbe72e823cb6
Autor:
María Dolores Juárez Rodríguez, Madison Marquette, Reneau Youngblood, Nilu Dhungel, Ascención Torres Escobar, Stanimir S. Ivanov, Ana-Maria Dragoi
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
Neisseria gonorrhoeae (Ng) is a uniquely adapted human pathogen and the etiological agent of gonorrhea, a sexually transmitted disease. Ng has developed numerous mechanisms to avoid and actively suppress innate and adaptive immune responses. Ng succe
Externí odkaz:
https://doaj.org/article/2d56f8e65e1e4b869dd8dde057de176a
Autor:
Madison Catalanotto, Joel Markus Vaz, Camille Abshire, Reneau Youngblood, Min Chu, Herbert Levine, Mohit Kumar Jolly, Ana-Maria Dragoi
Publikováno v:
Translational Oncology, Vol 39, Iss , Pp 101837- (2024)
Background: Epithelial-to-mesenchymal transition (EMT) is a developmental program that consists of the loss of epithelial features concomitant with the acquisition of mesenchymal features. Activation of EMT in cancer facilitates the acquisition of ag
Externí odkaz:
https://doaj.org/article/5618596db8ab40e98c31036f2823a2d7
Publikováno v:
Microbial Cell, Vol 10, Iss 1, Pp 1-17 (2022)
Host membranes are inherently critical for niche homeostasis of vacuolar pathogens. Thus, intracellular bacteria frequently encode the capacity to regulate host lipogenesis as well as to modulate the lipid composition of host membranes. One membrane
Externí odkaz:
https://doaj.org/article/ea36248c10e74ebf8b6ad2c21d997225
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
The tumor microenvironment (TME) is the source of important cues that govern epithelial-to-mesenchymal transition (EMT) and facilitate the acquisition of aggressive traits by cancer cells. It is now recognized that EMT is not a binary program, and ca
Externí odkaz:
https://doaj.org/article/927dd107d2f74d339f0ad6822669b856
Autor:
Stanimir S Ivanov, Reneau Castore, Maria Dolores Juarez Rodriguez, Magdalena Circu, Ana-Maria Dragoi
Publikováno v:
PLoS Pathogens, Vol 17, Iss 12, p e1010184 (2021)
Dynamic reorganization of the actin cytoskeleton dictates plasma membrane morphogenesis and is frequently subverted by bacterial pathogens for entry and colonization of host cells. The human-adapted bacterial pathogen Neisseria gonorrhoeae can coloni
Externí odkaz:
https://doaj.org/article/94f8176e3a2240d086756b60b6ddf493
Autor:
Natalie Carroll, Reneau Youngblood, Alena Smith, Ana-Maria Dragoi, Brian A. Salvatore, Elahe Mahdavian
Publikováno v:
Biomedicines, Vol 10, Iss 11, p 2906 (2022)
Fusarochromanone is an experimental drug with unique and potent anti-cancer activity. Current cancer therapies often incorporate a combination of drugs to increase efficacy and decrease the development of drug resistance. In this study, we used drug
Externí odkaz:
https://doaj.org/article/4837b7f55379409191f278a714a51db4
Autor:
Helene Tournu, Jennifer Carroll, Brian Latimer, Ana-Maria Dragoi, Samantha Dykes, James Cardelli, Tracy L Peters, Karen E Eberle, Glen E Palmer
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171145 (2017)
The fungal vacuole is a large acidified organelle that performs a variety of cellular functions. At least a sub-set of these functions are crucial for pathogenic species of fungi, such as Candida albicans, to survive within and invade mammalian tissu
Externí odkaz:
https://doaj.org/article/fa1b4889e65b408495d5ffedc4f469eb
Publikováno v:
PLoS Pathogens, Vol 12, Iss 12, p e1006088 (2016)
Vacuolar bacterial pathogens are sheltered within unique membrane-bound organelles that expand over time to support bacterial replication. These compartments sequester bacterial molecules away from host cytosolic immunosurveillance pathways that indu
Externí odkaz:
https://doaj.org/article/e62f2d98c8964c4f8de2a9caf7df8d4a