Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Ana-María Zárate"'
Autor:
Andrés Laserna, Julián E. Barahona-Correa, Laura Figueroa, Ana-María Zárate, José Foti, Sarita Mejía, Camilo Rosas
Publikováno v:
Revista Universitas Medica, Vol 57, Iss 1, Pp 132-133 (2016)
Externí odkaz:
https://doaj.org/article/43ae46b508024a37a56a76ee2ad2d769
Autor:
Pedro Farias, Richard Alcorn, Daniel Trnka, Manuel Flores, Delia Rodrigo, Eliezer Olivares, Ana María Zárate Moreno
Esta publicación forma parte de la agenda de conocimiento de la División de Innovación para Servir al Ciudadano del BID, orientada hacia la modernización de la gestión pública. Es una contribución para que los responsables de políticas públi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0b84fe70dd4094bec5b1e2465310cff
https://doi.org/10.18235/0004329
https://doi.org/10.18235/0004329
Autor:
Ana María Zárate, Camilo López-Alarcón, Juan David Figueroa, Eduardo Fuentes-Lemus, Michael J. Davies
Publikováno v:
Figueroa, J D, Zárate, A M, Fuentes-Lemus, E, Davies, M J & López-Alarcón, C 2020, ' Formation and characterization of crosslinks, including Tyr-Trp species, on one electron oxidation of free Tyr and Trp residues by carbonate radical anion ', RSC Advances, vol. 10, no. 43, pp. 25786-25800 . https://doi.org/10.1039/d0ra04051g
Dityrosine and ditryptophan bonds have been implied in protein crosslinking. This is associated with oxidative stress conditions including those involved in neurodegenerative pathologies and age-related processes. Formation of dityrosine and ditrypto
Autor:
Jaime Meléndez, Matías González-Quiroz, Felipe Oyarzun-Ampuero, Christian Espinosa-Bustos, Adam Aguirre, Ana María Zárate, Simón Guerrero, Miriam Caimano, Angélica Fierro, Andrea Calcaterra, Cristian O. Salas, Lucia Di Marcotullio, Elena Loricchio, Andrew F. G. Quest
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 8372, p 8372 (2021)
Volume 22
Issue 16
International Journal of Molecular Sciences, Vol 22, Iss 8372, p 8372 (2021)
Volume 22
Issue 16
The Smoothened (SMO) receptor is the most druggable target in the Hedgehog (HH) pathway for anticancer compounds. However, SMO antagonists such as vismodegib rapidly develop drug resistance. In this study, new SMO antagonists having the versatile pur
Autor:
Mario Faúndez, Jaime Mella, Radek Jorda, Iván Brito, Denisa Hendrychová, José Brea, Ana María Zárate, Ricardo A. Tapia, Alan R. Cabrera, Vladimír Kryštof, Cristian O. Salas, Christian Espinosa-Bustos, María Isabel Loza
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 1, p 161 (2019)
International Journal of Molecular Sciences
Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
instname
Volume 21
Issue 1
International Journal of Molecular Sciences
Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
instname
Volume 21
Issue 1
We designed, synthesized, and evaluated novel 2,6,9-trisubstituted purine derivatives for their prospective role as antitumor compounds. Using simple and efficient methodologies, 31 compounds were obtained. We tested these compounds in vitro to draw
Autor:
Jaime Mella, Christian Espinosa-Bustos, Ana María Zárate, Cristian O. Salas, Jeanluc Bertrand, Vladimír Kryštof, Hana Dostálová, Radek Jorda, Alejandro Castro
Publikováno v:
Bioorganic chemistry. 94
Bcr-Abl and Btk kinases are among the targets that have been considered for the treatment of leukemia. Therefore, several strategies have focused on the use of inhibitors as chemotherapeutic tools to treat these types of leukemia, such as imatinib (f
Autor:
Jaime Pizarro, Rodrigo Segura, Margot Paulino, Hugo Cerecetto, Ana María Zárate, Brenda Vera, Javier Varela, Mercedes González, Karina Vázquez, Cristian O. Salas, Christian Espinosa-Bustos
Publikováno v:
Archiv der PharmazieREFERENCES. 353(1)
Continuing with a program to develop new quinone derivatives as biologically active compounds, we designed and synthesized a new series of aryloxy-quinones, which were evaluated in vitro against Trypanosoma cruzi in epimastigote form. Chemical modifi
Autor:
Margarita E. Aliaga, Javiera Cortés-Ríos, Eduardo Fuentes-Lemus, Juan David Figueroa, Joaquín Medina, Maria Rodriguez-Fernandez, Camilo López-Alarcón, Ana María Zárate
Publikováno v:
Analytical Biochemistry. 608:113904
Amongst the available methodologies for protein determination, the bicinchoninic acid (BCA) assay highlights for its simplicity, sensitivity, repeatability and reproducibility. Nevertheless, in spite that the general principle behind this methodology
Autor:
Patricio Iturriaga-Vásquez, Carlos F. Lagos, Jaime Mella-Raipán, Hernán Pessoa-Mahana, Christian Espinosa-Bustos, Ricardo A. Tapia, Ana María Zárate, Gonzalo Recabarren-Gajardo, Javier Romero-Parra, C. David Pessoa-Mahana
Publikováno v:
Archiv der Pharmazie. 348:81-88
A series of N-acyl-2,5-dimethoxyphenyl-1H-benzimidazoles were designed based on a CoMFA model for cannabinoid receptor type 1 (CB1) ligands. Compounds were synthesized and radioligand binding affinity assays were performed. Eight novel benzimidazoles
Autor:
Ana María Zárate-Rivera, Rufino Díaz-Uribe, Octavio Cardona-Nunez, Alejandro Cornejo-Rodriguez, Fermín Granados-Agustín, Elizabeth Percino-Zacarías
Publikováno v:
Optik. 125:667-670
An overview of the settings of the planes for the filters and observed patterns in the Hartmann and Ronchi tests is presented. Also a new set of filters for both test were developed. In a similar way, it is easy to extend this analysis to the Shack�