Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Ana-Laura Jordán Garrote"'
Autor:
Carina A. Bäuerlein, Musga Qureischi, Zeinab Mokhtari, Paula Tabares, Christian Brede, Ana-Laura Jordán Garrote, Simone S. Riedel, Martin Chopra, Simone Reu, Anja Mottok, Estibaliz Arellano-Viera, Carolin Graf, Miriam Kurzwart, Katharina Schmiedgen, Hermann Einsele, Matthias Wölfl, Paul-Gerhardt Schlegel, Andreas Beilhack
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Acute graft-versus-host disease (aGvHD) is a severe and often life-threatening complication of allogeneic hematopoietic cell transplantation (allo-HCT). AGvHD is mediated by alloreactive donor T-cells targeting predominantly the gastrointestinal trac
Externí odkaz:
https://doaj.org/article/88450728038c452190d0abd979f290b8
Autor:
Eliana Ribechini, James A. Hutchinson, Sabine Hergovits, Marion Heuer, Jörg Lucas, Ulrike Schleicher, Ana-Laura Jordán Garrote, Sarah J. Potter, Paloma Riquelme, Heike Brackmann, Nora Müller, Hartmann Raifer, Ingolf Berberich, Magdalena Huber, Andreas Beilhack, Michael Lohoff, Christian Bogdan, Matthias Eyrich, Heike M. Hermanns, Edward K. Geissler, Manfred B. Lutz
Publikováno v:
Blood Advances, Vol 1, Iss 14, Pp 947-960 (2017)
Abstract: Granulocyte-macrophage colony-stimulating factor (GM-CSF) controls proliferation and survival of myeloid cells including monocytes. Here, we describe a time-dependent licensing process driven by GM-CSF in murine Ly6Chigh and human CD14+ mon
Externí odkaz:
https://doaj.org/article/01939da1159e4606bd40390d8e10d0d3
Autor:
Martin Chopra, Isabell Lang, Steffen Salzmann, Christina Pachel, Sabrina Kraus, Carina A Bäuerlein, Christian Brede, Ana-Laura Jordán Garrote, Katharina Mattenheimer, Miriam Ritz, Stefanie Schwinn, Carolin Graf, Viktoria Schäfer, Stefan Frantz, Hermann Einsele, Harald Wajant, Andreas Beilhack
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e75737 (2013)
Multiple activities are ascribed to the cytokine tumor necrosis factor (TNF) in health and disease. In particular, TNF was shown to affect carcinogenesis in multiple ways. This cytokine acts via the activation of two cell surface receptors, TNFR1, wh
Externí odkaz:
https://doaj.org/article/ac81b820406a4aebb816b1c76c1495ef
Autor:
Simone S Riedel, Anja Mottok, Christian Brede, Carina A Bäuerlein, Ana-Laura Jordán Garrote, Miriam Ritz, Katharina Mattenheimer, Andreas Rosenwald, Hermann Einsele, Bjarne Bogen, Andreas Beilhack
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52398 (2012)
BackgroundMultiple myeloma (MM) is a B-cell malignancy, where malignant plasma cells clonally expand in the bone marrow of older people, causing significant morbidity and mortality. Typical clinical symptoms include increased serum calcium levels, re
Externí odkaz:
https://doaj.org/article/16fcb994eb0e4dbb8a5b728ea8b2449a
Autor:
Ariane Brunk, Eva Distler, Wolfgang Herr, Dirk Tomsitz, Jana Albrecht, Udo F. Hartwig, Christian Brede, Anja Mottok, Andreas Beilhack, Andreas Mades, Ana-Laura Jordán-Garrote, Matthias Theobald, Michaela Frey, Elke Schnürer, Shamsul A. Khan
Publikováno v:
International Journal of Cancer. 138:1256-1268
Adoptive transfer of donor-derived cytolytic T-lymphocytes (CTL) has evolved as a promising strategy to improve graft-versus-leukemia (GvL) effects in allogeneic hematopoietic stem-cell transplantation. However, durable clinical responses are often h
Autor:
Manfred B. Lutz, Magdalena Huber, Ana-Laura Jordán Garrote, Michael Lohoff, James A. Hutchinson, Ulrike Schleicher, Sabine Hergovits, Paloma Riquelme, Jörg Lucas, Hartmann Raifer, Ingolf Berberich, Nora Müller, Edward K. Geissler, Marion Heuer, Andreas Beilhack, Matthias Eyrich, Heike M. Hermanns, Heike Brackmann, Eliana Ribechini, Christian Bogdan, Sarah J. Potter
Publikováno v:
Blood advances. 1(14)
Granulocyte-macrophage colony-stimulating factor (GM-CSF) controls proliferation and survival of myeloid cells including monocytes. Here, we describe a time-dependent licensing process driven by GM-CSF in murine Ly6Chigh and human CD14+ monocytes tha
Autor:
Christian Brede, Natalio Garbi, Julia Hartweg, Antoine-Emmanuel Saliba, Lukas Scheller, Duc Dung Le, Amy J. Wagers, Ana-Laura Jordán Garrote, Ehsan Vafadarnejad, Andreas Beilhack, Tim Steinfatt, Haroon Shaikh, Carina A. Bäuerlein, Simone S. Riedel, Ranecky Maria, Andreas Brandl, Nageswara Rao Tata, Manfred B. Lutz, Katja J. Ottmüller, Musga Qureischi, Hermann Einsele, Anja Mottok
Publikováno v:
Blood. 132:3315-3315
Acute graft versus host disease (aGVHD) remains a major complication in patients undergoing allogeneic hematopoietic stem cell transplantation (allo-HSCT), the only curative treatment for many malignant hematologic diseases. After initial priming in
Autor:
Rafaela Holtappels, Andrea Fick, Jeanette Baker, Harald Wajant, Matthias J. Reddehase, Thomas Müller, Daniela N. Männel, Andreas Brandl, Thorsten Winter, Viktoria Schäfer, Hermann Einsele, Carina A. Bäuerlein, Axel Seher, Jürgen Podlech, Sabrina Kraus, Johannes Polz, Eliana Ribechini, Tim Steinfatt, Sven Krappmann, Janina Kuen, Juliane Kums, Jorge Amich, Andreas Beilhack, Hidekazu Nishikii, Katja J. Ottmüller, Friederike Berberich-Siebelt, Anja Mottok, Manfred B. Lutz, Miriam Ritz, Ana-Laura Jordán-Garrote, Martin Vaeth, Katharina Mattenheimer, Christian Brede, Stefanie Schwinn, Martin Chopra, Marlene Biehl
Publikováno v:
The Journal of Experimental Medicine
Chopra, M, Biehl, M, Steinfatt, T, Brandl, A, Kums, J, Amich Elias, J, Vaeth, M, Kuen, J, Holtappels, R, Podlech, J, Mottok, A, Kraus, S, Jordán-Garrote, A-L, Bäuerlein, C A, Brede, C, Ribechini, E, Fick, A, Seher, A, Polz, J, Ottmüller, K J, Baker, J, Nishikii, H, Ritz, M, Mattenheimer, K, Schwinn, S, Winter, T, Schäfer, V, Krappmann, S, Einsele, H, Müller, T D, Reddehase, M J, Lutz, M B, Männel, D N, Berberich-Siebelt, F, Wajant, H & Beilhack, A 2016, ' Exogenous TNFR2 activation protects from acute GvHD via host T reg cell expansion ', Journal of Experimental Medicine, vol. 213, no. 9, pp. 1881–1900 . https://doi.org/10.1084/jem.20151563
Chopra, M, Biehl, M, Steinfatt, T, Brandl, A, Kums, J, Amich Elias, J, Vaeth, M, Kuen, J, Holtappels, R, Podlech, J, Mottok, A, Kraus, S, Jordán-Garrote, A-L, Bäuerlein, C A, Brede, C, Ribechini, E, Fick, A, Seher, A, Polz, J, Ottmüller, K J, Baker, J, Nishikii, H, Ritz, M, Mattenheimer, K, Schwinn, S, Winter, T, Schäfer, V, Krappmann, S, Einsele, H, Müller, T D, Reddehase, M J, Lutz, M B, Männel, D N, Berberich-Siebelt, F, Wajant, H & Beilhack, A 2016, ' Exogenous TNFR2 activation protects from acute GvHD via host T reg cell expansion ', Journal of Experimental Medicine, vol. 213, no. 9, pp. 1881–1900 . https://doi.org/10.1084/jem.20151563
Activation of TNFR2 with a novel agonist expands T reg cells in vivo and protects allo-HCT recipients from acute GvHD while sparing antilymphoma and antiinfectious properties of transplanted donor T cells.
Donor CD4+Foxp3+ regulatory T cells (T
Donor CD4+Foxp3+ regulatory T cells (T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f6a4988c207afd66c5d8de16a6bb555
https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/18764
https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/18764
Autor:
Eva, Distler, Jana, Albrecht, Ariane, Brunk, Shamsul, Khan, Elke, Schnürer, Michaela, Frey, Anja, Mottok, Ana-Laura, Jordán-Garrote, Christian, Brede, Andreas, Beilhack, Andreas, Mades, Dirk, Tomsitz, Matthias, Theobald, Wolfgang, Herr, Udo F, Hartwig
Publikováno v:
International journal of cancer. 138(5)
Adoptive transfer of donor-derived cytolytic T-lymphocytes (CTL) has evolved as a promising strategy to improve graft-versus-leukemia (GvL) effects in allogeneic hematopoietic stem-cell transplantation. However, durable clinical responses are often h
Autor:
Sabrina Kraus, Christian Brede, Viktoria von Krosigk, Andreas Beilhack, Anja Mottok, Harald Wajant, Katharina Mattenheimer, Martin Chopra, Marlene Biehl, Axelle Degla, Viktoria Schäfer, Carina A. Bäuerlein, Ana-Laura Jordán Garrote, Stefanie Krieger, Miriam Ritz, Simone S. Riedel, Hermann Einsele
Publikováno v:
Carcinogenesis. 34(6)
The cytokine tumor necrosis factor (TNF) has pleiotropic functions both in normal physiology and disease. TNF signals by the virtue of two cell surface receptors, TNF receptor 1 (TNFR1) and TNF receptor 2 (TNFR2). Exogenous TNF promotes experimental