Progress and challenges of lyotropic liquid crystalline nanoparticles for innovative therapies

Autor: Ana Vitoria Pupo Silvestrini, Bryan Wender Debiasi, Fabíola Garcia Praça, Maria Vitoria Lopes Badra Bentley

Publikováno v: International journal of pharmaceutics. 628

Since the late 20th century, we have witnessed a growing and substantial advance in nanomedicine, in part due to the development of multifunctional and multimodal nanoplatforms that have enabled improved efficacy, biocompatibility, and novel therapeu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::759d70dc005cbf58788242e7f893d5b3
https://pubmed.ncbi.nlm.nih.gov/36265664

Nanostructured lipid carrier co-delivering tacrolimus and TNF-α siRNA as an innovate approach to psoriasis

Autor: Juliana Santos Rosa Viegas, Ana Vitoria Pupo Silvestrini, Fabíola Silva Garcia Praça, Angelo Luis Caron, Isabella Suzuki, Marcelo Kravicz, Wanessa Silva Garcia Medina, José Orestes Del Ciampo, Maria Vitória Lopes Badra Bentley

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Since psoriasis is an immuno-mediated skin disease, long-term therapies are necessary for its treatment. In clinical investigations, tacrolimus (TAC), a macrolide immunosuppressive inhibitor of calcineurin, arises as an alternative for the treatment

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d9b6b201fc593c6af0f5d7e05e1eb0c
https://doi.org/10.1007/s13346-020-00723-6

Intradermal Application of Crotamine Induces Inflammatory and Immunological Changes In Vivo

Autor: Luana Henrique de Macedo, Maurício V. Mazzi, Maíra Felonato Mendes, Thiago Antônio Moretti de Andrade, Acácio Antônio Pigoso, Ana Vitoria Pupo Silvestrini

Publikováno v: Toxins, Vol 11, Iss 1, p 39 (2019)
Toxins
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Volume 11
Issue 1

Crotamine is a single-chain polypeptide with cell-penetrating properties, which is considered a promising molecule for clinical use. Nevertheless, its biosafety data are still scarce. Herein, we assessed the in vivo proinflammatory properties of crot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d48bbeb6ec8d695019ccb40cd7d45f6
http://www.mdpi.com/2072-6651/11/1/39

Mechanistic insights into functional characteristics of native crotamine

Autor: Joyce Maria Annichino Bizzacchi, Ana Laura Remédio Zeni Beretta, Flávia Lino Pollettini, Juliana de Oliveira Navarro, Ana Carolina Gomes da Silva, Deborah Maria de Paula Estevam, Armindo Antonio Alves, Daniel Batista da Cunha, Maurício V. Mazzi, Lilian Cristina Pereira, Ana Vitoria Pupo Silvestrini

Publikováno v: Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP

Made available in DSpace on 2018-12-11T16:52:35Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-05-01 The chemical composition of snake venoms is a complex mixture of proteins and peptides that can be pharmacologically active. Crotamine, a cel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad654091fe322cc07f03ab7bf61e7241
https://pubmed.ncbi.nlm.nih.gov/29574214