Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Ana Vinagre‐Aragón"'
Autor:
Sara Gomes, Alicia Garrido, Francesca Tonelli, Donina Obiang, Eduardo Tolosa, Maria José Martí, Javier Ruiz-Martínez, Ana Vinagre-Aragón, Haizea Hernandez-Eguiazu, Ioana Croitoru, Vicky L. Marshall, Theresa Koenig, Christoph Hotzy, Frank Hsieh, Marianna Sakalosh, Elizabeth Tengstrand, Shalini Padmanabhan, Kalpana Merchant, Christof Bruecke, Walter Pirker, Alexander Zimprich, Esther Sammler
Publikováno v:
npj Parkinson's Disease, Vol 9, Iss 1, Pp 1-4 (2023)
Abstract Elevated urine bis(monoacylglycerol)phosphate (BMP) levels have been found in gain-of-kinase function LRRK2 G2019S mutation carriers. Here, we have expanded urine BMP analysis to other Parkinson’s disease (PD) associated mutations and foun
Externí odkaz:
https://doaj.org/article/48b4e1d519164c9ca1e0284e3c294d10
A Set of Reliable Samples for the Study of Biomarkers for the Early Diagnosis of Parkinson's Disease
Autor:
Marcela Konjevod, Jorge Sáiz, Coral Barbas, Alberto Bergareche, Eva Ardanaz, José Ma Huerta, Ana Vinagre-Aragón, Ma Elena Erro, Ma Dolores Chirlaque, Eunate Abilleira, Jesús Ma Ibarluzea, Pilar Amiano
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
BackgroundParkinson's disease (PD) is a progressive neurodegenerative disorder, diagnosed according to the clinical criteria that occur in already advanced stages of PD. The definition of biomarkers for the early diagnosis of PD represents a challeng
Externí odkaz:
https://doaj.org/article/f74524fa4571478999e7957951bd2baf
Autor:
Ana Vinagre-Aragón, David Campo-Caballero, Elisabet Mondragón-Rezola, Lara Pardina-Vilella, Haizea Hernandez Eguiazu, Ana Gorostidi, Ioana Croitoru, Alberto Bergareche, Javier Ruiz-Martinez
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Parkinson's disease (PD) is characterized by a great clinical heterogeneity. Nevertheless, the biological drivers of this heterogeneity have not been completely elucidated and are likely to be complex, arising from interactions between genetic, epige
Externí odkaz:
https://doaj.org/article/099c309d09434779b9d4b0e5284ae56d
Autor:
Adolfo López de Munain, Jon Rodríguez-Antigüedad, M. Urtasun, Nora Imaz, Julia Echeverria, Juan Bautista Espinal, David Campo-Caballero, Pablo Iruzubieta, Ana Vinagre-Aragón, Jon Equiza, Txomin Alberdi
Publikováno v:
Journal of Clinical Neuroscience. 88:159-162
Botulism is a life-threatening presynaptic disorder of the neuromuscular transmission produced by the neurotoxin elaborated by the botulinum neurotoxin-producing clostridia. We describe the management of a case series of 14 patients, members of 5 dif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3e10644e3e4457b8c3d804c04d73287
https://doi.org/10.1016/j.jocn.2021.03.041
https://doi.org/10.1016/j.jocn.2021.03.041
Autor:
David Campo‐Caballero, Ana Vinagre‐Aragón, Javier Ruiz‐Martinez, Laura Naranjo, Raquel Ruiz‐García, Andrés Roncancio Clavijo, Felix González
Publikováno v:
Mov Disord Clin Pract
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f093b23b56fe1220b3582e6252a28447
https://doi.org/10.1002/mdc3.13389
https://doi.org/10.1002/mdc3.13389
A Set of Reliable Samples for the Study of Biomarkers for the Early Diagnosis of Parkinson's Disease
Autor:
Pilar Amiano, Alberto Bergareche, Marcela Konjevod, Ma Dolores Chirlaque, Mª Elena Erro, Ana Vinagre-Aragón, Eunate Abilleira, Coral Barbas, Jesús Mª Ibarluzea, Eva Ardanaz, Jorge Saiz, José Mª Huerta
Publikováno v:
Addi. Archivo Digital para la Docencia y la Investigación
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Background: The identification of biomarkers for the early diagnosis of Parkinson’s Disease (PD) might improve treatment and avoid complications. However, the search of such biomarkers is a real challenge. The main reason for this is that finding s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d52f0ac7fb8d05e6e3eb9cc30ed9dafa
https://pubmed.ncbi.nlm.nih.gov/35707037
https://pubmed.ncbi.nlm.nih.gov/35707037
Autor:
Teresa Ximelis, Eduardo Tolosa, Leticia Pérez Sisqués, Jonas Düring, Raja Sekhar Nirujogi, Francesc Valldeoriola, Alicia Garrido, Ioana Croitoru, Laura Molina Porcel, Alberto Bergareche-Yarza, Dario R. Alessi, Esther Sammler, Ying Fan, Neringa Pratuseviciute, Roy N. Alcalay, Cristina Malagelada, Ana Gorostidi Pagola, Sara Gomes, María José Martí, Laura Paternain Markinez, Javier Ruiz-Martínez, Elisabet Mondragón-Rezola, Ana Vinagre-Aragón, Richard A. Hickman, Shalini Padmanabhan
Publikováno v:
Acta Neuropathologica
Heterozygous gain-of-kinase function variants in LRRK2 (leucine-rich repeat kinase 2) cause 1–2% of all cases of Parkinson’s disease (PD) albeit with incomplete and age-dependent penetrance. All pathogenic LRRK2 mutations reside within the two ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e18b8a16950f159c1167b789f7006b3d
https://doi.org/10.1007/s00401-021-02325-z
https://doi.org/10.1007/s00401-021-02325-z
Autor:
Ioana Croitoru, Francesc Valldeoriola, Shalini Padmanabhana, Ana Vinagre Aragón, María José Martí, Jonas Duering, Raja Sekhar Nirujogi, Javier Ruiz Martínez, Roy N. Alcalay, Neringa Pratuseviciute, Laura Paternain Markinez, Eduardo Tolosa, Ana Gorostidi Pagola, Richard A. Hickman, Alicia Garrido, Ying Fan, Alberto Bergareche-Yarza, Dario R. Alessi, Elisabet Mondragón Rezola, Esther Sammler
Gain-of kinase function variants in LRRK2 (leucine-rich repeat kinase 2) cause Parkinson’s disease (PD), albeit with incomplete and age-dependent penetrance, offering the prospect of disease-modifying treatment strategies via LRRK2 kinase inhibitio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c676ec2ed06a0a6d283889388f41302
https://doi.org/10.1101/2021.01.28.21249614
https://doi.org/10.1101/2021.01.28.21249614
Autor:
Nuria López Ariztegui, Marina Mata Alvarez-Santullano, Iciar Tegel, Francisca Almeida, Pilar Sarasa, Rosa Rojo, Fernando Rico-Villademoros, Javier Abril Jaramillo, Pedro Bermejo, Carmen Borrue, Nuria Caballol, Marina Campins Romeu, Pedro Clavero, Juan García Caldentey, Victor Gómez Mayordomo, Carmen Labandeira, Glòria Martí Andrés, Juan Carlos Martínez Castrillo, Javier Martinez Poles, Teresa Muñoz, José María Salom, Carmen Valderrama Martín, Ana Vinagre Aragón
Publikováno v:
REVISTA DE NEUROLOGIA
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
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r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
Opicapone is a catechol-O-methyl-transferase (iCOMT) inhibitor authorized in Europe in 2016 and indicated as adjunctive therapy to preparations of levodopa/ DOPA decarboxylase inhibitors in adult patients with Parkinson's disease and end-of-dose moto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbb1f6170d3cedd5909a718655cf1224
https://fundanet.iislafe.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=15285
https://fundanet.iislafe.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=15285
Autor:
Ana Vinagre-Aragón, Joy Adewusi, Karen Ruth O’Connor, Richard A. Grünewald, Aijaz Khan, Panagiotis Zis, Marios Hadjivassiliou
Publikováno v:
Journal of the Neurological Sciences. 392:3-7
Pain is a frequent and debilitating non-motor symptom of Idiopathic Parkinson's Disease (IPD). The present study investigated the prevalence of pain and specifically peripheral neuropathic pain (PNP) in IPD, and ascertained any impact of PNP on quali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::314a287a1ccfbe6c6cf381baa72e92c1
https://doi.org/10.1016/j.jns.2018.06.022
https://doi.org/10.1016/j.jns.2018.06.022