Zobrazeno 1 - 10 of 22 pro vyhledávání: '"Ana Villar‐Garea"'
1
Akademický článek
Fine mapping of posttranslational modifications of the linker histone H1 from Drosophila melanogaster.
Autor: Ana Villar-Garea, Axel Imhof
Publikováno v: PLoS ONE, Vol 3, Iss 2, p e1553 (2008)
The linker histone H1 binds to the DNA in between adjacent nucleosomes and contributes to chromatin organization and transcriptional control. It is known that H1 carries diverse posttranslational modifications (PTMs), including phosphorylation, lysin
Externí odkaz: https://doaj.org/article/95136b088c2741bba10eb9c8d976dc85
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3
Chromatin regulation by Histone H4 acetylation at Lysine 16 during cell death and differentiation in the myeloid compartment
Autor: Carlos López-Larrea, María Jesús Cañal, Marija Dmitrijeva, Jesús Vallejo-Díaz, Anne K. Voss, Patricia C Pruneda, Inmaculada Hernández-López, Beatriz Suarez-Alvarez, Núria Sima-Teruel, Tim Thomas, María Begoña González García, Raúl F. Pérez, Virginia Lopez, Rainer Deutzmann, Teresa Bernal, Ana Villar-Garea, Marta I. Sierra, Antonella Carella, Ana C. Carrera, Daniel Rico, Osvaldo Graña-Castro, Alejandra Sanjuan-Pla, Elena Diaconu, Cristina Mangas, Cecilia Ferrero, Mario F. Fraga, Ana Pando-Sandoval, Pablo Santamarina, Laura Santos, Luis Valledor, David G. Pisano, Clara Bueno, Cristina Prieto, Cristina Bravo, Alejandro Vaquero, Juan Luis Fernández-Morera, María-Dolores Chiara, Francisco Rodríguez, Gustavo F. Bayón, Estela García-Toraño, Agustín F. Fernández, Ana Salas, Thalia Belmonte, Rafael Diaz de la Guardia, Juan Ramón Tejedor, Edward Seto, Milagros Balbín, Enrique Colado, Inés Sáenz-de-Santa-María, Rocío G. Urdinguio, Amparo Vayá, Luis Rodrigo, Pablo Menendez, Olivia García-Suárez, José M Ricart, Ramon M. Rodriguez
Publikováno v: Dipòsit Digital de la UB
Universidad de Barcelona
Scopus
Nucleic Acids Research
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
RUO. Repositorio Institucional de la Universidad de Oviedo
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Repisalud
Instituto de Salud Carlos III (ISCIII)
Digital.CSIC. Repositorio Institucional del CSIC
NUCLEIC ACIDS RESEARCH
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
Histone H4 acetylation at Lysine 16 (H4K16ac) is a key epigenetic mark involved in gene regulation, DNA repair and chromatin remodeling, and though it is known to be essential for embryonic development, its role during adult life is still poorly unde
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee781ba1d7bf3975d5365c81edeecf72
http://hdl.handle.net/2445/174855
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6
Epigenetic disruption of ribosomal RNA genes and nucleolar architecture in DNA methyltransferase 1 (Dnmt1) deficient cells
Autor: Wendy A. Bickmore, Jesús Espada, Ingrid Grummt, Gernot Längst, Juan C. Stockert, Helena Orozco, Angeles Juarranz, Vanessa P. Moreno, Agustín Aranda, Mario F. Fraga, Attila Németh, Santiago Ropero, Esteban Ballestar, Manel Esteller, Ana Villar-Garea, Raffaella Santoro, Lidia Lopez-Serra
Publikováno v: Nucleic Acids Research
Dipòsit Digital de la UB
Universidad de Barcelona
Espada, J, Ballestar, E, Santoro, R, Fraga, M F, Villar-Garea, A, Németh, A, Lopez-Serra, L, Ropero, S, Aranda, A, Orozco, H, Moreno, V, Juarranz, A, Stockert, J C, Längst, G, Grummt, I, Bickmore, W & Esteller, M 2007, ' Epigenetic disruption of ribosomal RNA genes and nucleolar architecture in DNA methyltransferase 1 (Dnmt1) deficient cells ', Nucleic Acids Research, vol. 35, no. 7, pp. 2191-8 . https://doi.org/10.1093/nar/gkm118
The nucleolus is the site of ribosome synthesis in the nucleus, whose integrity is essential. Epigenetic mechanisms are thought to regulate the activity of the ribosomal RNA (rRNA) gene copies, which are part of the nucleolus. Here we show that human
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0759ddc42c65621ea3c5e96cf8737e53
https://doi.org/10.1093/nar/gkm118
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7
The extended AT-hook is a novel RNA binding motif
Autor: Karina Zillner, Michael Filarsky, Ana Villar-Garea, Gernot Längst, Rainer Merkl, Attila Németh, Ingrid Araya
Publikováno v: RNA Biology
The AT-hook has been defined as a DNA binding peptide motif that contains a glycine-arginine-proline (G-R-P) tripeptide core flanked by basic amino acids. Recent reports documented variations in the sequence of AT-hooks and revealed RNA binding activ
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f0e8e091ba757808b73b6459139c949
https://pubmed.ncbi.nlm.nih.gov/26156556
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8
Release of Hypoacetylated and Trimethylated Histone H4 Is an Epigenetic Marker of Early Apoptosis
Autor: Cristina Largo, Juan Casado, Manuel Boix-Chornet, Antonio Núñez, Rosalia Caballero, J. Ignacio Casal, Luis Franco, Mario F. Fraga, Manel Esteller, Jesús Espada, Ana Villar-Garea, Juan C. Cigudosa, Esteban Ballestar
Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname
Dipòsit Digital de la UB
Universidad de Barcelona
11 p.-5 fig.-1 fig. supl.
Nuclear events such as chromatin condensation, DNA cleavage at internucleosomal sites, and histone release from chromatin are recognized as hallmarks of apoptosis. However, there is no complete understanding of the mole
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73f10a5e076dfe85922efaf7a75180e0
https://doi.org/10.1074/jbc.m601136200
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9
Histone deacetylase inhibitors: Understanding a new wave of anticancer agents
Autor: Ana Villar-Garea, Manel Esteller
Publikováno v: International Journal of Cancer. 112:171-178
Cancer is as much an epigenetic disease as it is a genetic and cytogenetic disease. The discovery that drastic changes in DNA methylation and histone modifications are commonly found in human tumors has inspired various laboratories and pharmaceutica
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa0850aba74648598b638989fdfc47c9
https://doi.org/10.1002/ijc.20372
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10
DNA Demethylating Agents and Chromatin-Remodelling Drugs: Which, How and Why?
Autor: Manel Esteller, Ana Villar-Garea
Publikováno v: Current Drug Metabolism. 4:22-31
DNA hypermethylation at the CpG dinucleotides clustered in "islands" in the promoter regions of genes causes transcriptional repression through the remodelling of chromatin. Aberrant methylation patterns of tumor suppressor genes and their subsequent
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d9dcd0e15a94ab12473ff6c5512259d
https://doi.org/10.2174/1389200033336757
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