Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Ana Vieira-Saecker"'
Autor:
Annett Halle, Matthias Brückner, Christiane Kummer, Marc Beyer, Heela Sarlus, Ana Vieira-Saecker, Stephanie Schwartz, Christina Ising, Michael T. Heneka, Eicke Latz, Joachim L. Schultze, Markus P. Kummer, Kristian Händler, Angelika Griep
Publikováno v:
The EMBO journal 40(24), e108662 (2021). doi:10.15252/embj.2021108662
The EMBO Journal
The EMBO Journal
Chronic neuroinflammation is a pathogenic component of Alzheimer’s disease (AD) that may limit the ability of the brain to clear amyloid deposits and cellular debris. Tight control of the immune system is therefore key to sustain the ability of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90cb05e330be04d3ebfcce0c4bc7c292
https://pub.dzne.de/record/163394
https://pub.dzne.de/record/163394
Autor:
David Blum, Douglas T. Golenbock, Frederic Brosseron, Shuangshuang Zhang, Dario Tejera, Shadi Albasset, Michael T. Heneka, Angelika Griep, Rakez Kayed, Susanne V. Schmidt, Róisín M. McManus, Sabine Opitz, James Stunden, Christina Ising, Stephanie Schwartz, Eicke Latz, Carmen Venegas, Luc Buée, Francesco Santarelli, Ana Vieira-Saecker, Hannah Scheiblich
Publikováno v:
Alzheimer's & Dementia. 16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::559f4f2a848f461ad4047518a2bd3d9b
https://doi.org/10.1002/alz.039815
https://doi.org/10.1002/alz.039815
Autor:
Shuangshuang Zhang, David Blum, Ana Vieira-Saecker, Carmen Venegas, Rakez Kayed, Hannah Scheiblich, Douglas T. Golenbock, Maximilian Merten, Shadi Albasset, Susanne V. Schmidt, Eicke Latz, Luc Buée, Frederic Brosseron, Sabine Opitz, Angelika Griep, Francesco Santarelli, Christina Ising, James Stunden, Róisín M. McManus, Michael T. Heneka, Dario Tejera, Stephanie Schwartz
Publikováno v:
Nature
Nature, 2019, 575 (7784), pp.669-673. ⟨10.1038/s41586-019-1769-z⟩
Nature 575(7784), 669-673 (2019). doi:10.1038/s41586-019-1769-z
Nature, Nature Publishing Group, 2019, 575 (7784), pp.669-673. ⟨10.1038/s41586-019-1769-z⟩
Nature, 2019, 575 (7784), pp.669-673. ⟨10.1038/s41586-019-1769-z⟩
Nature
Nature, Nature Publishing Group, 2019, 575 (7784), pp.669-673. ⟨10.1038/s41586-019-1769-z⟩
International audience; Alzheimer's disease is characterized by the accumulation of amyloid-beta in plaques, aggregation of hyperphosphorylated tau in neurofibrillary tangles and neuroinflammation, together resulting in neurodegeneration and cognitiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee285b788aaa24d0e733106578c031d3
https://pubmed.ncbi.nlm.nih.gov/32296063
https://pubmed.ncbi.nlm.nih.gov/32296063
Autor:
Jochen Walter, Francesco Santarelli, Matthias Geyer, Angelika Griep, Ellen Gelpi, Stephanie Schwartz, Markus P. Kummer, Sathish Kumar, Eicke Latz, Douglas T. Golenbock, Michael T. Heneka, Michael Beilharz, Bernardo S. Franklin, Ana Vieira-Saecker, Carmen Venegas, Rebecca Brinkschulte, Tobias Dierkes, Dario Tejera, Dietmar Riedel
Publikováno v:
Nature
Nature 552(7685), 355-361 (2017). doi:10.1038/nature25158
Nature
The spreading of pathology within and between brain areas is a hallmark of neurodegenerative disorders. In patients with Alzheimer's disease, deposition of amyloid-beta is accompanied by activation of the innate immune system and involves inflammasom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::166393c57d4785a9bb9587fe730527c2
https://hdl.handle.net/11858/00-001M-0000-002E-A451-A11858/00-001M-0000-002E-A455-211858/00-001M-0000-002E-A454-411858/00-001M-0000-002E-A453-6
https://hdl.handle.net/11858/00-001M-0000-002E-A451-A11858/00-001M-0000-002E-A455-211858/00-001M-0000-002E-A454-411858/00-001M-0000-002E-A453-6
Autor:
Ellen Gelpi, Annett Halle, Markus P. Kummer, Daisy Axt, Andrea Delekate, Anita Remus, Douglas T. Golenbock, Te-Chen Tzeng, Andrea Stutz, Eicke Latz, Martin Korte, Stephanie Schwartz, Ana Vieira-Saecker, Michael T. Heneka, Angelika Griep
Publikováno v:
Nature 493(7434), 674-678 (2012). doi:10.1038/nature11729
Nature
Nature
Alzheimer's disease is the world's most common dementing illness. Deposition of amyloid-beta peptide drives cerebral neuroinflammation by activating microglia. Indeed, amyloid-beta activation of the NLRP3 inflammasome in microglia is fundamental for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1f0acc3be46a195a5da2f36c54b2d1b
https://pub.dzne.de/record/136774
https://pub.dzne.de/record/136774
Autor:
Michael T. Heneka, Ana Vieira-Saecker, Ellen Gelpi, Markus P. Kummer, Daisy Axt, Johannes Roth, Frank Jessen, Thomas Vogl, Angelika Griep
Publikováno v:
The journal of neuroscience 32(49), 17824-17829 (2012). doi:10.1523/JNEUROSCI.1504-12.2012
Neuroinflammation plays a fundamental role in the pathogenesis of Alzheimer's disease (AD), resulting in the extensive activation of microglial and astroglial cells. Here we describe the role of myeloid-related protein Mrp14, a recently described amp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e4166a9d4ca0544a472282c5b1f86b8
https://pubmed.ncbi.nlm.nih.gov/23223301
https://pubmed.ncbi.nlm.nih.gov/23223301