Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Ana Victoria Ponce‐Bobadilla"'
Autor:
Diego Valderrama, Ana Victoria Ponce‐Bobadilla, Sven Mensing, Holger Fröhlich, Sven Stodtmann
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 13, Iss 1, Pp 41-53 (2024)
Abstract Recently, the use of machine‐learning (ML) models for pharmacokinetic (PK) modeling has grown significantly. Although most of the current approaches use ML techniques as black boxes, there are only a few that have proposed interpretable ar
Externí odkaz:
https://doaj.org/article/b01c91b33a9843feb724d969b1c2d471
Publikováno v:
Mathematics in Applied Sciences and Engineering, Vol 2, Iss 1, Pp 32-54 (2021)
The quest for a deeper understanding of the cancer growth and spread process focuses on the naturally multiscale nature of cancer invasion, which requires an appropriate multiscale modeling and analysis approach. The cross-talk between the dynamics o
Externí odkaz:
https://doaj.org/article/fa0d5914e7b147338d793d3bd470ab90
Autor:
Ana Victoria Ponce-Bobadilla, Sven Stodtmann, Mong-Jen Chen, Insa Winzenborg, Sven Mensing, Jonas Blaes, Tobias Haslberger, Loic Laplanche, Ingeborg Dreher, Nael M. Mostafa
Publikováno v:
Clinical Pharmacokinetics. 62:623-634
Autor:
Ana Victoria Ponce-Bobadilla, Sven Stodtmann, Doerthe Eckert, Wen Zhou, Wei Liu, Mohamed-Eslam F. Mohamed
Publikováno v:
Clinical Pharmacokinetics. 62:101-112
Upadacitinib, an oral selective and reversible Janus kinase (JAK) inhibitor, showed favorable efficacy and safety in patients with moderate-to-severe ulcerative colitis (UC). The objective was to characterize upadacitinib pharmacokinetics in UC patie
Publikováno v:
2018 MATRIX Annals ISBN: 9783030382292
Stochastic models of chemical reactions are needed in many contexts in which the copy numbers of species are low, but only the simplest models can be treated analytically. However, direct simulation of computational models for systems with many compo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e82b53395cb73141a65183b5a9b3e14
https://doi.org/10.1007/978-3-030-38230-8_10
https://doi.org/10.1007/978-3-030-38230-8_10
Publikováno v:
RECERCAT (Dipòsit de la Recerca de Catalunya)
Recercat. Dipósit de la Recerca de Catalunya
instname
Recercat: Dipósit de la Recerca de Catalunya
Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Recercat. Dipósit de la Recerca de Catalunya
instname
Recercat: Dipósit de la Recerca de Catalunya
Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Scratch assays are in vitro methods for studying cell migration. In these experiments, a scratch is made on a cell monolayer and recolonisation of the scratched region is imaged to quantify cell migration rates. Typically, scratch assays are modelled
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94e22d5ab6b58bb871f38da151d36f2e
http://hdl.handle.net/2072/446120
http://hdl.handle.net/2072/446120
Publikováno v:
Mathematical Medicine and Biology. 35(2)
The tumor control probability (TCP) is the probability that a treatment regimen of radiation therapy (RT) eradicates all tumor cells in a given tissue. To decrease the toxic effects on healthy cells, RT is usually delivered over a period of weeks in
Autor:
Thomas Carraro, Philip K. Maini, Tomás Alarcón, Helen M. Byrne, Simone Balocco, Ana Victoria Ponce Bobadilla, Anna Meseguer, Eduard Sarró, Jazmine Arévalo
Publikováno v:
Journal of The Royal Society Interface. 16:20180709
The scratch assay is an in vitro technique used to assess the contribution of molecular and cellular mechanisms to cell migration. The assay can also be used to evaluate therapeutic compounds before clinical use. Current quantification methods of scr
Autor:
Valderrama, Diego1,2 (AUTHOR), Ponce‐Bobadilla, Ana Victoria3 (AUTHOR), Mensing, Sven3 (AUTHOR), Fröhlich, Holger1,2 (AUTHOR) holger.froehlich@scai.fraunhofer.de, Stodtmann, Sven3 (AUTHOR) sven.stodtmann@abbvie.com
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology. Jan2024, Vol. 13 Issue 1, p41-53. 13p.
Publikováno v:
Clinical Pharmacology & Therapeutics; Sep2023, Vol. 114 Issue 3, p499-503, 5p