Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Ana Verma"'
Autor:
Albert Grinshpun, Douglas Russo, Wen Ma, Ana Verma, Francisco Hermida-Prado, Shira Sherman, Giorgio Gaglia, Sheheryar Kabraji, Gregory Kirkner, Melissa E. Hughes, Nancy U. Lin, Zachary Sandusky, Agostina Nardone, Cristina Guarducci, Quang-De Nguyen, Sandro Santagata, Zsuzsanna Nagy, Rinath Jeselsohn
Publikováno v:
npj Breast Cancer, Vol 10, Iss 1, Pp 1-12 (2024)
Abstract The ESR1 ligand binding domain activating mutations are the most prevalent genetic mechanism of acquired endocrine resistance in metastatic hormone receptor-positive breast cancer. These mutations confer endocrine resistance that remains est
Externí odkaz:
https://doaj.org/article/7c7a103652a4404eac1f649798184d56
Autor:
Peter Tsvetkov, Shannon Coy, Boryana Petrova, Margaret Dreishpoon, Ana Verma, Mai Abdusamad, Jordan Rossen, Lena Joesch-Cohen, Ranad Humeidi, Ryan D. Spangler, John K. Eaton, Evgeni Frenkel, Mustafa Kocak, Steven M. Corsello, Svetlana Lutsenko, Naama Kanarek, Sandro Santagata, Todd R. Golub
Publikováno v:
Science
Copper is an essential cofactor for all organisms, and yet it becomes toxic if concentrations exceed a threshold maintained by evolutionarily conserved homeostatic mechanisms. How excess copper induces cell death, however, is unknown. Here, we show i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::823d9210499ec728084765ef9240f1cb
https://europepmc.org/articles/PMC9273333/
https://europepmc.org/articles/PMC9273333/
Autor:
Giorgio Gaglia, Sheheryar Kabraji, Danae Rammos, Yang Dai, Ana Verma, Shu Wang, Caitlin E. Mills, Mirra Chung, Johann S. Bergholz, Shannon Coy, Jia-Ren Lin, Rinath Jeselsohn, Otto Metzger, Eric P. Winer, Deborah A. Dillon, Jean J. Zhao, Peter K. Sorger, Sandro Santagata
Publikováno v:
Nature cell biology. 24(3)
Proliferation is a fundamental trait of cancer cells, but its properties and spatial organization in tumours are poorly characterized. Here we use highly multiplexed tissue imaging to perform single-cell quantification of cell cycle regulators and th
Autor:
Sandro Santagata, Nathanael S. Gray, Theresa D. Manz, Nami Kim, Nobufumi Sekino, Xiao Zhen Zhou, Futoshi Suizu, Giorgio Gaglia, Dipikaa Akshinthala, Shizhong Ke, Benika J. Pinch, Manuel Hidalgo, Babara Wegiel, Kun Ping Lu, Senthil K. Muthuswamy, Yutaka Nezu, Kenoki Ohuchida, Shin Kibe, Gerburg M. Wulf, Chenxi Qiu, Nir London, Tae Ho Lee, Yoshinao Oda, Ana Verma, Kazuhiro Koikawa, John G. Clohessy, Masafumi Nakamura
Publikováno v:
Cell. 184:4753-4771.e27
Pancreatic ductal adenocarcinoma (PDAC) is characterized by notorious resistance to current therapies attributed to inherent tumor heterogeneity and highly desmoplastic and immunosuppressive tumor microenvironment (TME). Unique proline isomerase Pin1
Autor:
Pablo Solís-Muñoz, Christopher Willars, Juan Carlos López, Michael A. Heneghan, William Bernal, Julia Wendon, Georg Auzinger, Ana Verma
Publikováno v:
Journal of Infection. 66:80-86
There are no studies regarding to these effects in patients with severe liver dysfunction.The aims of this study were to characterize voriconazole hepatotoxicity in patients with severe liver dysfunction and to compare it with a matched cohort treate