Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Ana V Villar"'
Autor:
Cecilia Montalvo, Ana V Villar, David Merino, Raquel García, Miguel Ares, Miguel Llano, Manuel Cobo, María A Hurlé, J Francisco Nistal
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35635 (2012)
BackgroundIn clinical studies, myocardial remodeling in aortic valve stenosis appears to be more favorable in women than in men, even after menopause. In the present study, we assessed whether circulating androgens contribute to a less favorable myoc
Externí odkaz:
https://doaj.org/article/c0ae32a71e434f96838c3c000749c75f
Autor:
Ana V Villar, Manuel Cobo, Miguel Llano, Cecilia Montalvo, Francisco González-Vílchez, Rafael Martín-Durán, María A Hurlé, J Francisco Nistal
Publikováno v:
PLoS ONE, Vol 4, Iss 12, p e8476 (2009)
BackgroundTGF-beta1 is involved in cardiac remodeling through an auto/paracrine mechanism. The contribution of TGF-beta1 from plasmatic source to pressure overload myocardial remodeling has not been analyzed. We investigated, in patients with valvula
Externí odkaz:
https://doaj.org/article/b69c4889c40646068e960877e82eb065
Autor:
Raquel García, Ana B. Salido-Medina, Aritz Gil, David Merino, Jenny Gómez, Ana V. Villar, Francisco González-Vílchez, María A. Hurlé, J. Francisco Nistal
Publikováno v:
Cells, Vol 9, Iss 4, p 833 (2020)
Pressure overload in patients with aortic stenosis (AS) induces an adverse remodeling of the left ventricle (LV) in a sex-specific manner. We assessed whether a sex-specific miR-29b dysregulation underlies this sex-biased remodeling pattern, as has b
Externí odkaz:
https://doaj.org/article/c67ec688d3cb412ea8bcc36380edf94a
Autor:
Jorge RuizdelRio, Pedro Muñoz, Patricia Carreira, David Maestro, Jose L. Pablos, Ana Palanca, Jesus Merino, Anna Serrano-Mollar, Ramon Merino, Esther Tamayo, Marcos Lopez-Hoyos, Federico Diaz-Gonzalez, Victor Martinez-Taboada, Ana V. Villar
Publikováno v:
Journal of Immunology.
Systemic sclerosis (SSc) is an autoimmune disease that affects skin and multiple internal organs. TGF-β, a central trigger of cutaneous fibrosis, activates fibroblasts with the involvement of the stress-inducible chaperone heat shock protein 90 isof
Autor:
Jorge Ruiz del Rio, Carlos Sanchez-Cano, David Maestro, Ana Palanca, Aitziber L. Cortajarena, Antonio Aires, Ana V. Villar, Kalotina Geraki, Elena Lopez-Martinez, Irantzu Llarena
Publikováno v:
Chemical Science
Chem. Sci., 2021,12, 2480-2487
UCrea Repositorio Abierto de la Universidad de Cantabria
Universidad de Cantabria (UC)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Chem. Sci., 2021,12, 2480-2487
UCrea Repositorio Abierto de la Universidad de Cantabria
Universidad de Cantabria (UC)
Digital.CSIC. Repositorio Institucional del CSIC
instname
© 2021 The Author(s).
Protein-based hybrid nanomaterials have recently emerged as promising platforms to fabricate tailored multifunctional biologics for biotechnological and biomedical applications. This work shows a simple, modular, and versa
Protein-based hybrid nanomaterials have recently emerged as promising platforms to fabricate tailored multifunctional biologics for biotechnological and biomedical applications. This work shows a simple, modular, and versa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5564afc78b1b9469219a07ef85a2a76
https://zenodo.org/record/4420048
https://zenodo.org/record/4420048
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
Cardiac fibrosis is a pathological process that presents a continuous overproduction of extracellular matrix (ECM) components in the myocardium, which negatively influences the progression of many cardiac diseases. Transforming growth factor β (TGF
Autor:
Aritz Gil, Raquel García, Francisco González-Vílchez, David Merino, Ana V. Villar, Ana B. Salido-Medina, J. Francisco Nistal, María A. Hurlé, J. Gómez
Publikováno v:
Cells
Cells 2020, 9(4), 833
UCrea Repositorio Abierto de la Universidad de Cantabria
instname
Cells, Vol 9, Iss 833, p 833 (2020)
Digital.CSIC. Repositorio Institucional del CSIC
Volume 9
Issue 4
Cells 2020, 9(4), 833
UCrea Repositorio Abierto de la Universidad de Cantabria
instname
Cells, Vol 9, Iss 833, p 833 (2020)
Digital.CSIC. Repositorio Institucional del CSIC
Volume 9
Issue 4
Pressure overload in patients with aortic stenosis (AS) induces an adverse remodeling of the left ventricle (LV) in a sex-specific manner. We assessed whether a sex-specific miR-29b dysregulation underlies this sex-biased remodeling pattern, as has b
Autor:
Ashley E. Russell, Alexandra Sneider, Kenneth W. Witwer, Paolo Bergese, Suvendra N. Bhattacharyya, Alexander Cocks, Emanuele Cocucci, Uta Erdbrügger, Juan M. Falcon-Perez, David W. Freeman, Thomas M. Gallagher, Shuaishuai Hu, Yiyao Huang, Steven M. Jay, Shin-ichi Kano, Gregory Lavieu, Aleksandra Leszczynska, Alicia M. Llorente, Quan Lu, Vasiliki Mahairaki, Dillon C. Muth, Nicole Noren Hooten, Matias Ostrowski, Ilaria Prada, Susmita Sahoo, Tine Hiorth Schøyen, Lifu Sheng, Deanna Tesch, Guillaume Van Niel, Roosmarijn E. Vandenbroucke, Frederik J. Verweij, Ana V. Villar, Marca Wauben, Ann M. Wehman, Hang Yin, David Raul Francisco Carter, Pieter Vader
Paracrine and endocrine roles have increasingly been ascribed to extracellular vesicles (EVs) generated by multicellular organisms. Central to the biogenesis, content, and function of EVs are their delimiting lipid bilayer membranes. To evaluate rese
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2659::1879cf8f19e1462fee5c92de08567c05
https://zenodo.org/record/3365957
https://zenodo.org/record/3365957
Autor:
David Merino, Carlos Fernández-Hernando, Arantxa González, Nathan L. Price, J. Francisco Nistal, María A. Hurlé, Raquel García, Javier Beaumont, Ana V. Villar
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1852:1520-1530
Transforming growth factor-β (TGF-β) induces miR-21 expression which contributes to fibrotic events in the left ventricle (LV) under pressure overload. SMAD effectors of TGF-β signaling interact with DROSHA to promote primary miR-21 processing int
Autor:
David Merino, Mónica Tramullas, Juan Francisco Nistal, Catalina Ribas, María A. Hurlé, Luis Santiago Sazatornil Ruiz, Raquel García, Sofía Cabezudo, Ana V. Villar
Publikováno v:
Cardiovasc Res 2016; 110 (3): 331-345
UCrea Repositorio Abierto de la Universidad de Cantabria
instname
UCrea Repositorio Abierto de la Universidad de Cantabria
instname
Aims TGF-ß regulates tissue fibrosis: TGF-ß promotes fibrosis, whereas bone morphogenetic protein (BMP)-7 is antifibrotic. To demonstrate that (i) left ventricular (LV) remodelling after pressure overload is associated with disequilibrium in the si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80ce5f408f7b3ca6829de8f50d660d4f
http://hdl.handle.net/10902/11021
http://hdl.handle.net/10902/11021