Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Ana Tufegdžić Vidaković"'
Autor:
Ana Tufegdžić Vidaković, Ronald C. Conaway, Laura Milligan, Joan W. Conaway, Juston C. Weems, Stefan Boeing, Aengus Stewart, Michelle Harreman, Michelle Neumann, Jesper Q. Svejstrup, Ambrosius P. Snijders, David Tollervey, Richard Mitter, Vesela Encheva, Gavin Kelly, Anna Herlihy, Marta Rodríguez-Martínez, Liam Gaul
Publikováno v:
Cell
Tufegdžić Vidaković, A, Mitter, R, Kelly, G P, Neumann, M, Harreman, M, Rodríguez-Martínez, M, Herlihy, A, Weems, J C, Boeing, S, Encheva, V, Gaul, L, Milligan, L, Tollervey, D, Conaway, R C, Conaway, J W, Snijders, A P, Stewart, A & Svejstrup, J Q 2020, ' Regulation of the RNAPII Pool Is Integral to the DNA Damage Response ', Cell, vol. 180, no. 6, pp. 1245-1261.e21 . https://doi.org/10.1016/j.cell.2020.02.009
Tufegdžić Vidaković, A, Mitter, R, Kelly, G P, Neumann, M, Harreman, M, Rodríguez-Martínez, M, Herlihy, A, Weems, J C, Boeing, S, Encheva, V, Gaul, L, Milligan, L, Tollervey, D, Conaway, R C, Conaway, J W, Snijders, A P, Stewart, A & Svejstrup, J Q 2020, ' Regulation of the RNAPII Pool Is Integral to the DNA Damage Response ', Cell, vol. 180, no. 6, pp. 1245-1261.e21 . https://doi.org/10.1016/j.cell.2020.02.009
Summary In response to transcription-blocking DNA damage, cells orchestrate a multi-pronged reaction, involving transcription-coupled DNA repair, degradation of RNA polymerase II (RNAPII), and genome-wide transcription shutdown. Here, we provide insi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::705e7dedfee7a71270bb1cb309fc1377
Autor:
Rajbir Nath Batra, Aviezer Lifshitz, Ana Tufegdzic Vidakovic, Suet-Feung Chin, Ankita Sati-Batra, Stephen-John Sammut, Elena Provenzano, H. Raza Ali, Ali Dariush, Alejandra Bruna, Leigh Murphy, Arnie Purushotham, Ian Ellis, Andrew Green, Francine E. Garrett-Bakelman, Chris Mason, Ari Melnick, Samuel A. J. R. Aparicio, Oscar M. Rueda, Amos Tanay, Carlos Caldas
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Understanding the molecular mechanisms underlying DNA methylation in cancer and its clinical relevance remains crucial. Here, the authors study RRBS-based profiles of 1538 breast tumours and 244 normal breast tissues from the METABRIC cohort and repo
Externí odkaz:
https://doaj.org/article/7832b4cd7ff242839e4e5e73265c879e
Autor:
Stephin J Vervoort, Olivier G de Jong, M Guy Roukens, Cynthia L Frederiks, Jeroen F Vermeulen, Ana Rita Lourenço, Laura Bella, Ana Tufegdzic Vidakovic, José L Sandoval, Cathy Moelans, Miranda van Amersfoort, Margaret J Dallman, Alejandra Bruna, Carlos Caldas, Edward Nieuwenhuis, Elsken van der Wall, Patrick Derksen, Paul van Diest, Marianne C Verhaar, Eric W-F Lam, Michal Mokry, Paul J Coffer
Publikováno v:
eLife, Vol 7 (2018)
The expression of the transcription factor SOX4 is increased in many human cancers, however, the pro-oncogenic capacity of SOX4 can vary greatly depending on the type of tumor. Both the contextual nature and the mechanisms underlying the pro-oncogeni
Externí odkaz:
https://doaj.org/article/36ce755b8cc24e3d9cea3f932f2ee24e
Autor:
Ana Tufegdzic Vidakovic, Oscar M. Rueda, Stephin J. Vervoort, Ankita Sati Batra, Mae Akilina Goldgraben, Santiago Uribe-Lewis, Wendy Greenwood, Paul J. Coffer, Alejandra Bruna, Carlos Caldas
Publikováno v:
Cell Reports, Vol 13, Iss 11, Pp 2480-2490 (2015)
The transforming growth factor beta (TGF-β) signaling pathway exerts opposing effects on cancer cells, acting as either a tumor promoter or a tumor suppressor. Here, we show that these opposing effects are a result of the synergy between SMAD3, a do
Externí odkaz:
https://doaj.org/article/fcd484aaf1534aa1962787015da627c1