Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Ana Teresa Azevedo Sachetto"'
Autor:
Ana Teresa Azevedo Sachetto, Jackson Gabriel Miyamoto, Alexandre Keiji Tashima, Ana Olívia de Souza, Marcelo Larami Santoro
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
The venom of the Brazilian pit viper Bothrops jararaca (BjV) is a complex mixture of molecules, and snake venom metalloproteinases (SVMP) and serine proteinases (SVSP) are the most abundant protein families found therein. Toxins present in BjV trigge
Externí odkaz:
https://doaj.org/article/491643877a284e338c0c34f739171e07
Autor:
Camila Martos Thomazini, Ana Teresa Azevedo Sachetto, Cynthia Zaccanini de Albuquerque, Vânia Gomes de Moura Mattaraia, Ana Karina de Oliveira, Solange Maria de Toledo Serrano, Ivo Lebrun, Katia Cristina Barbaro, Marcelo Larami Santoro
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 9, p e0009715 (2021)
Patients bitten by snakes consistently manifest a bleeding tendency, in which thrombocytopenia, consumption coagulopathy, mucous bleeding, and, more rarely, thrombotic microangiopathy, are observed. Von Willebrand factor (VWF) is required for primary
Externí odkaz:
https://doaj.org/article/19e7e53c3d6b49728785982860419355
Publikováno v:
Toxins, Vol 14, Iss 10, p 661 (2022)
Viperidae snakes are the most important agents of snakebites in Brazil. The protein composition of snake venoms has been frequently analyzed by means of electrophoretic techniques, but the interaction of proteins in venoms has barely been addressed.
Externí odkaz:
https://doaj.org/article/28d5a62afdb74ed2a8fefec13b2e5652
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 6, p e0008379 (2020)
Few studies have addressed gene expression of hemostasis-related factors during acute thrombo-hemorrhagic diseases. Bites by the lanced-headed viper Bothrops jaracaca induce rapid hemostatic disturbances in victims, leading to systemic bleedings, thr
Externí odkaz:
https://doaj.org/article/5bd0b5d25db84ae4826aadb1c48958c1
Autor:
Percíllia Victória Santos de Oliveira, Sheila Garcia-Rosa, Ana Teresa Azevedo Sachetto, Ana Iochabel Soares Moretti, Victor Debbas, Tiphany Coralie De Bessa, Nathalia Tenguan Silva, Alexandre da Costa Pereira, Daniel Martins-de-Souza, Marcelo Larami Santoro, Francisco Rafael Martins Laurindo
Publikováno v:
Redox Biology, Vol 22, Iss , Pp - (2019)
Redox-related plasma proteins are candidate reporters of protein signatures associated with endothelial structure/function. Thiol-proteins from protein disulfide isomerase (PDI) family are unexplored in this context. Here, we investigate the occurren
Externí odkaz:
https://doaj.org/article/332b5527aa7043708192a2c0345653aa
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 12, Iss 10, p e0006774 (2018)
Snakebites are a major Collective Health problem worldwide. In Brazil, Bothrops jararaca snake venom (BjV) evokes hemostatic disturbances, bleeding manifestations, and redox status imbalance. Specific antivenom therapy, although efficacious to revert
Externí odkaz:
https://doaj.org/article/c0bf4107f1514247825325b4d0b26f45
Autor:
Ana Teresa Azevedo Sachetto
Publikováno v:
Biblioteca Digital de Teses e Dissertações da USPUniversidade de São PauloUSP.
Os acidentes ofídicos são considerados um grande problema de saúde pública e no Estado de São Paulo a serpente Bothrops jararaca é o agente considerado mais relevante epidemiologicamente. O antiveneno é o único medicamento oficialmente aprova
Publikováno v:
Current Drug Targets. 23:1573-1577
Abstract: The coronavirus 2019 (COVID-19) pandemic is caused by severe acute respiratory syn-drome coronavirus 2 (SARS-CoV-2) virus. Infection with SARS-CoV-2 is associated with acute respiratory distress syndrome, thrombosis and a high rate of morta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22f09aa1f97443874b16d4674e1acd46
https://doi.org/10.2174/1389450123666220926144432
https://doi.org/10.2174/1389450123666220926144432
Publikováno v:
Current Opinion in Hematology. 29:266-274
This review evaluates the different methods used to measure levels of tissue factor (TF) in plasma and on extracellular vesicles (EVs). Levels of TF-positive (TF+) EVs in blood are increased in a variety of diseases, such as cancer, sepsis, and viral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d081d41a652ebbc18f917c4e841ee8b
https://doi.org/10.1097/moh.0000000000000730
https://doi.org/10.1097/moh.0000000000000730
Publikováno v:
Immunological Reviews. 312:61-75
Tissue factor (TF) is a procoagulant protein released from activated host cells, such as monocytes, and tumor cells on extracellular vesicles (EVs). TF + EVs are observed in the circulation of patients with various types of diseases. In this review,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe42887af8984e419b4944133f86792a
https://doi.org/10.1111/imr.13106
https://doi.org/10.1111/imr.13106