Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Ana Teodosio"'
Autor:
Neale Harrison, Lauren Richardson, Chiara Pallini, Ines Morano, Elizabeth Jinks, Jamie Cowley, Hujo Chan, Harriet J. Hill, Aekkachai Tuekprakhon, Zhi Li, Cristina Matas de las Heras, Ana Teodosio, Andrea S. Lavado, Robert Moring, Ayesha Ashraf, Timothy R. Dafforn, Dimitris K. Grammatopoulos, John Gordon, Catherine A. Brady, Lawrence S. Young, Nicholas M. Barnes, Zania Stamataki, Omar S. Qureshi
Publikováno v:
Frontiers in Virology, Vol 3 (2023)
IntroductionThe engagement of the SARS-CoV-2 spike protein with ACE2 is a critical step for viral entry to human cells, and, therefore, blocking this interaction is a major determinant of the efficacy of monoclonal antibody therapeutics and vaccine e
Externí odkaz:
https://doaj.org/article/8359357ba2624784b5140879793cd87d
Akademický článek
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Autor:
Owen J. Sansom, Martin Bushell, Anne E. Willis, Joanne Edwards, John Le Quesne, William J. Faller, Heather J. McKinnon, Martin E. Swarbrick, Neil P. Jones, Christopher G. Proud, Nahum Sonenberg, Kevin M. Haigis, Nicola Valeri, Georgios Vlachogiannis, Andrew D. Campbell, Joseph A. Waldron, Rene Jackstadt, Joshua D. Leach, Emma Stanway, Kerri McArthur, Anne Cheasty, Craig MacKay, Laura McDonald, Rachael C.L. Smith, Dustin J. Flanagan, Rachel A. Ridgway, Kathryn Gilroy, Arafath K. Najumudeen, Ewan M. Smith, Sebastian May-Wilson, David M. Gay, Georgios Kanellos, Ana Teodosio, Leah Officer, Kathryn Pennel, Nikola Vlahov, George L. Skalka, Constantinos Alexandrou, John R.P. Knight
All supplemental figures and legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cee3a26e547749f005f869f86f6004e
https://doi.org/10.1158/2159-8290.22540555
https://doi.org/10.1158/2159-8290.22540555
Autor:
Owen J. Sansom, Martin Bushell, Anne E. Willis, Joanne Edwards, John Le Quesne, William J. Faller, Heather J. McKinnon, Martin E. Swarbrick, Neil P. Jones, Christopher G. Proud, Nahum Sonenberg, Kevin M. Haigis, Nicola Valeri, Georgios Vlachogiannis, Andrew D. Campbell, Joseph A. Waldron, Rene Jackstadt, Joshua D. Leach, Emma Stanway, Kerri McArthur, Anne Cheasty, Craig MacKay, Laura McDonald, Rachael C.L. Smith, Dustin J. Flanagan, Rachel A. Ridgway, Kathryn Gilroy, Arafath K. Najumudeen, Ewan M. Smith, Sebastian May-Wilson, David M. Gay, Georgios Kanellos, Ana Teodosio, Leah Officer, Kathryn Pennel, Nikola Vlahov, George L. Skalka, Constantinos Alexandrou, John R.P. Knight
KRAS-mutant colorectal cancers are resistant to therapeutics, presenting a significant problem for ∼40% of cases. Rapalogs, which inhibit mTORC1 and thus protein synthesis, are significantly less potent in KRAS-mutant colorectal cancer. Using Kras-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f56670615fce027f717d8d9f47081b8
https://doi.org/10.1158/2159-8290.c.6549409
https://doi.org/10.1158/2159-8290.c.6549409
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Neale Harrison, Lauren Richardson, Chiara Pallini, Ines Morano, Elizabeth Jinks, Jamie Cowley, Hujo Chan, Harriet J Hill, Cristina Matas de las Heras, Ana Teodosio, Andrea S Lavado, Timothy R Dafforn, Dimitris K Grammatopoulos, John Gordon, Catherine A Brady, Lawrence S Young, Nicholas M Barnes, Zania Stamataki, Omar S Qureshi
The engagement of the SARS-CoV-2 spike protein with ACE2 is a critical step for viral entry to human cells and accordingly blocking this interaction is a major determinant of the efficacy of monoclonal antibody therapeutics and vaccine-elicited serum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49fc2eadd7fcf70f0b9f3092b3d38880
https://doi.org/10.1101/2022.06.24.496409
https://doi.org/10.1101/2022.06.24.496409
Autor:
Ana Teodósio Chícharo, Mónica Rebelo, Ana Rita Lopes, Maria João Saavedra, Maria Filipa Paramés, Ana Rita Araújo, Ana Rita Cruz-Machado, Luísa Pinto, Susana Capela
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Fetal autoimmune atrioventricular block (AVB) is a rare but potentially life-threatening condition. It results from the passage of maternal anti-SSA/Ro or Anti SSB/La auto-antibodies into the fetal circulation, leading to inflammation and fibrosis of
Externí odkaz:
https://doaj.org/article/be445955eafd4358ae2c5c5d7b4f1cb7
Autor:
John R P, Knight, Constantinos, Alexandrou, George L, Skalka, Nikola, Vlahov, Kathryn, Pennel, Leah, Officer, Ana, Teodosio, Georgios, Kanellos, David M, Gay, Sebastian, May-Wilson, Ewan M, Smith, Arafath K, Najumudeen, Kathryn, Gilroy, Rachel A, Ridgway, Dustin J, Flanagan, Rachael C L, Smith, Laura, McDonald, Craig, MacKay, Anne, Cheasty, Kerri, McArthur, Emma, Stanway, Joshua D, Leach, Rene, Jackstadt, Joseph A, Waldron, Andrew D, Campbell, Georgios, Vlachogiannis, Nicola, Valeri, Kevin M, Haigis, Nahum, Sonenberg, Christopher G, Proud, Neil P, Jones, Martin E, Swarbrick, Heather J, McKinnon, William J, Faller, John, Le Quesne, Joanne, Edwards, Anne E, Willis, Martin, Bushell, Owen J, Sansom
Publikováno v:
Cancer Discov
KRAS-mutant colorectal cancers (CRC) are resistant to therapeutics, presenting a significant problem for ~40% of cases. Rapalogs, which inhibit mTORC1 and thus protein synthesis, are significantly less potent in KRAS-mutant CRC. Using Kras-mutant mou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c2f8097c7234ed04603f0d786b945e20
https://pubmed.ncbi.nlm.nih.gov/33328217
https://pubmed.ncbi.nlm.nih.gov/33328217