Origin and Development of the Adipose Tissue, a Key Organ in Physiology and Disease

Autor: Esmeralda Parra-Peralbo, Ana Talamillo, Rosa Barrio

Publikováno v: Frontiers in Cell and Developmental Biology, Vol 9 (2021)

Adipose tissue is a dynamic organ, well known for its function in energy storage and mobilization according to nutrient availability and body needs, in charge of keeping the energetic balance of the organism. During the last decades, adipose tissue h

Externí odkaz: https://doaj.org/article/caee7956e4d2415aa6821b33f68a54e9

Scavenger receptors mediate the role of SUMO and Ftz-f1 in Drosophila steroidogenesis.

Autor: Ana Talamillo, Leire Herboso, Lucia Pirone, Coralia Pérez, Monika González, Jonatan Sánchez, Ugo Mayor, Fernando Lopitz-Otsoa, Manuel S Rodriguez, James D Sutherland, Rosa Barrio

Publikováno v: PLoS Genetics, Vol 9, Iss 4, p e1003473 (2013)

SUMOylation participates in ecdysteroid biosynthesis at the onset of metamorphosis in Drosophila melanogaster. Silencing the Drosophila SUMO homologue smt3 in the prothoracic gland leads to reduced lipid content, low ecdysone titers, and a block in t

Externí odkaz: https://doaj.org/article/1c5f74eb635241b79c752302f2715341

The role of SUMOylation during development

Autor: Ana Talamillo, Rosa Barrio, Leiore Ajuria, Immacolata Giordano, Orhi Barroso-Gomila, Ugo Mayor, Marco Grillo

Publikováno v: Addi. Archivo Digital para la Docencia y la Investigación
instname
Biochemical Society Transactions
Addi: Archivo Digital para la Docencia y la Investigación
Universidad del País Vasco

During the development of multicellular organisms, transcriptional regulation plays an important role in the control of cell growth, differentiation and morphogenesis. SUMOylation is a reversible post-translational process involved in transcriptional

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e5502a8d68c18a89eebf5af189986f6
https://zenodo.org/record/4327636

Genetic manipulation of LKB1 elicits lethal metastatic prostate cancer

Autor: Marc Núnez-Ollé, Jan Trka, Bora Gurel, Jesús M. Paramio, Ana R. Cortazar, Juana M. Flores, Ivana Hermanova, Alfredo Caro-Maldonado, Johann S. de Bono, Roger R. Gomis, Suzanne Carreira, Verónica Torrano, Patricia Zúñiga-García, Antonio Gómez-Muñoz, Fernando Salvador, Cristian Suárez-Cabrera, Rosa Barrio, Guillermo Velasco, Mar Lorente, Iris Lodewijk, Natalia Martín-Martín, José I. López, Sonia Fernández-Ruiz, Arkaitz Carracedo, Amaia Arruabarrena-Aristorena, Marc Guiu, Ianire Astobiza, Amaia Zabala-Letona, James D. Sutherland, Laura Camacho, Lorea Valcarcel-Jimenez, Anabel Martinez-Romero, Jose M. Lizcano, Mariona Graupera, Ana Talamillo

Publikováno v: Journal of Experimental Medicine
E-Prints Complutense: Archivo Institucional de la UCM
Universidad Complutense de Madrid
E-Prints Complutense. Archivo Institucional de la UCM
instname
Dipòsit Digital de la UB
Universidad de Barcelona
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
The Journal of Experimental Medicine

This study unravels an unprecedented murine model of lethal metastatic prostate cancer, based on the combined deletion of Pten and Lkb1. Importantly, minimal activity of LKB1 is sufficient to hamper prostate cancer cell aggressiveness, thus redefinin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3284771176a4b94cfd84580d59b1f24

Expression of the Scavenger Receptor Class B type I (SR-BI) family in Drosophila melanogaster

Autor: Coralia Pérez, Leire Herboso, Rosa Barrio, Ana Talamillo

Publikováno v: The International Journal of Developmental Biology. 55:603-611

In mammals, cholesterol is transformed into steroid hormones in the adrenal gland, the ovaries or the testes. The Scavenger Receptors Class B Type I (SR-BI) are membrane proteins that belong to the CD36 family and participate in the selective uptake

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19187556f493344e63f284d83acc1b5f
https://doi.org/10.1387/ijdb.103254lh