Comprehensive Approach to Genomic and Immune Profiling: Insights of a Real-World Experience in Gynecological Tumors

Autor: Iván Prieto-Potin, Franklin Idrovo, Ana Suárez-Gauthier, María Díaz-Blázquez, Laura Astilleros-Blanco de Córdova, Cristina Chamizo, Sandra Zazo, Nerea Carvajal, Almudena López-Sánchez, Sandra Pérez-Buira, Carmen Laura Aúz-Alexandre, Rebeca Manso, Jenifer Plaza-Sánchez, Virginia de Lucas-López, Nuria Pérez-González, Sara Martín-Valle, Ion Cristóbal, Victoria Casado, Jesús García-Foncillas, Federico Rojo

Publikováno v: Diagnostics, Vol 12, Iss 8, p 1903 (2022)

Gynecological cancer accounts for an elevated incidence worldwide requiring responsiveness regarding its care. The comprehensive genomic approach agrees with the classification of certain tumor types. We evaluated 49 patients with gynecological tumor

Externí odkaz: https://doaj.org/article/5997035934bb459c94fd59bc4cba53f2

A comparison of EGFR mutation testing methods in lung carcinoma: direct sequencing, real-time PCR and immunohistochemistry.

Autor: Bárbara Angulo, Esther Conde, Ana Suárez-Gauthier, Carlos Plaza, Rebeca Martínez, Pilar Redondo, Elisa Izquierdo, Belén Rubio-Viqueira, Luis Paz-Ares, Manuel Hidalgo, Fernando López-Ríos

Publikováno v: PLoS ONE, Vol 7, Iss 8, p e43842 (2012)

The objective of this study is to compare two EGFR testing methodologies (a commercial real-time PCR kit and a specific EGFR mutant immunohistochemistry), with direct sequencing and to investigate the limit of detection (LOD) of both PCR-based method

Externí odkaz: https://doaj.org/article/85272ea918f442c09ea38f3534cb8548

Data from Antitumor activity and molecular effects of the novel heat shock protein 90 inhibitor, IPI-504, in pancreatic cancer

Autor: Manuel Hidalgo, Akhilesh Pandey, Antonio Jimeno, Christian Fritz, Margaret Read, Jeffrey Tong, Anna Solomon, Xian Feng Zhang, Fernando López-Ríos, Ana Suárez-Gauthier, Anuradha Nalli, Elena García-García, Aik Choon Tan, Raghothama Chaerkady, Dongweon Song

Targeting Hsp90 is an attractive strategy for anticancer therapy because the diversity and relevance of biological processes are regulated by these proteins in most cancers. However, the role and mode of action of Hsp90 inhibitors in pancreatic cance

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0690c76d61d810f28385d6a95183ba00
https://doi.org/10.1158/1535-7163.c.6531134.v1

PD-L1 testing based on the SP142 antibody in metastatic triple-negative breast cancer: summary of an expert round-table discussion

Autor: Ana Suárez-Gauthier, Vicente Peg, María Ángeles López-García, Ángel Concha López, Federico Rojo, Gloria Peiró, Tomás García-Caballero, Laura Comerma, Irune Ruiz

Publikováno v: Minerva: Repositorio Institucional de la Universidad de Santiago de Compostela
Universidad de Santiago de Compostela (USC)
Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
instname

Triple-negative breast cancer (TNBC) is more aggressive than other breast cancer subtypes. TNBC is characterized by increased expression of Programmed Death-ligand 1 (PD-L1), a signal used by many tumors to escape the immune response. Expression of P

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7233abf261cfe02ad5ea8ea31f167566
https://doi.org/10.2217/fon-2020-1100

Retrospective study assessing the role of MRI in the diagnostic procedures for early breast carcinoma: a correlation of new foci in the MRI with tumor pathological features

Autor: C. Miró, F. J. Pérez, P. Quevedo, J. De La Cruz, Manuel Marcos, M. Herrero, Cristina Marquez, Laura G. Estévez, L Ugidos, I. Calvo-Plaza, M. García-Aranda, Ana Suárez-Gauthier, M. Parras, Manuel Hidalgo

Publikováno v: Clinical and Translational Oncology. 15:205-210

Use of breast magnetic resonance imaging (MRI) to detect breast cancer has generated significant debate. We analyze the role of breast MRI in the detection of additional disease and the need to perform additional biopsies in early breast carcinoma pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faf31e396d1eede75b1e177dd2fe500f
https://doi.org/10.1007/s12094-012-0899-7