Výsledky vyhledávání - "Ana Sílvia G Lima"

Akademický článek

Halofuginone has anti-proliferative effects in acute promyelocytic leukemia by modulating the transforming growth factor beta signaling pathway.

Autor: Lorena L de Figueiredo-Pontes, Patricia A Assis, Bárbara A A Santana-Lemos, Rafael H Jácomo, Ana Sílvia G Lima, Aglair B Garcia, Carolina H Thomé, Amélia G Araújo, Rodrigo A Panepucci, Marco A Zago, Arnon Nagler, Roberto P Falcão, Eduardo M Rego

Publikováno v: PLoS ONE, Vol 6, Iss 10, p e26713 (2011)

Promyelocytic leukemia-retinoic acid receptor alpha (PML-RARα) expression in acute promyelocytic leukemia (APL) impairs transforming growth factor beta (TGFβ) signaling, leading to cell growth advantage. Halofuginone (HF), a low-molecular-weight al

Externí odkaz: https://doaj.org/article/c92e0b8c5a3d4c8d8b7ef1a9b6cf080e

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Akademický článek

The Combination of Gefitinib With ATRA and ATO Induces Myeloid Differentiation in Acute Promyelocytic Leukemia Resistant Cells

Publikováno v: Frontiers in Oncology, Vol 11 (2021)

In approximately 15% of patients with acute myeloid leukemia (AML), total and phosphorylated EGFR proteins have been reported to be increased compared to healthy CD34+ samples. However, it is unclear if this subset of patients would benefit from EGFR

Externí odkaz: https://doaj.org/article/7571ff921fee43699747c4b3cd44329e

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Características hematológicas e perfil de expressão de antígenos mielóides de pacientes com leucemia promielocítica aguda: análise de fatores prognósticos para o desenvolvimento da síndrome do ácido retinóico Hematological features and expression profile of myeloid antigens of acute promyelocytic leukemia patients: analysis of prognostic factors for development of the retinoic acid syndrome

Autor: Flávia Leite Souza Santos, Adriana I. Dore, Ana Sílvia G. Lima, Aglair B. Garcia, Marco A. Zago, Edgar G. Rizzatti, Jorge Elias Jr, Roberto Passetto Falcão, Eduardo Magalhães Rego

Publikováno v: Revista da Associação Médica Brasileira, Vol 50, Iss 3, Pp 286-292 (2004)

OBJETIVO: A leucemia promielocítica aguda (LPA) apresenta uma boa resposta ao tratamento com o ácido all trans retinóico (ATRA). Entretanto, alguns pacientes desenvolvem uma complicação grave chamada síndrome do ácido retinóico (SAR). O objet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doajarticles::6a231a63e68c07e140438a392053b731
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302004000300036

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[Hematological features and expression profile of myeloid antigens of acute promyelocytic leukemia patients: analysis of prognostic factors for development of the retinoic acid syndrome]

Autor: Flávia Leite Souza, Santos, Adriana I, Dore, Ana Sílvia G, Lima, Aglair B, Garcia, Marco A, Zago, Edgar G, Rizzatti, Jorge, Elias, Roberto Passetto, Falcão, Eduardo Magalhães, Rego

Publikováno v: Revista da Associacao Medica Brasileira (1992). 50(3)

Acute Promyelocytic Leukemia (APL) is characterized by its good response to treatment with all trans retinoic acid (ATRA). However, some patients receiving ATRA develop a serious complication called retinoid syndrome (RS). The objective of this study

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::df36c4ec715ef683a2a55e622b775a6a
https://pubmed.ncbi.nlm.nih.gov/15499481

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