Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Ana Sánchez-Díez"'
Autor:
Yoana Arroyo-Berdugo, Santos Alonso, Gloría Ribas, Maider Ibarrola-Villava, María Peña-Chilet, Conrado Martínez-Cadenas, Jesús Gardeazabal, Juan Antonio Ratón-Nieto, Ana Sánchez-Díez, Jesús María Careaga, Gorka Pérez-Yarza, Gregorio Carretero, Manuel Martín-González, Cristina Gómez-Fernández, Eduardo Nagore, Aintzane Asumendi, María Dolores Boyano
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e95522 (2014)
Single nucleotide-polymorphisms (SNPs) are a source of diversity among human population, which may be responsible for the different individual susceptibility to diseases and/or response to drugs, among other phenotypic traits. Several low penetrance
Externí odkaz:
https://doaj.org/article/ed535651f6244be6a3ebe2d9e5f35fa1
Autor:
Isabel Smith-Zubiaga, Montse Hervella, Santos Alonso, José Luis Díaz-Ramón, María Dolores Boyano, Saioa López, Neskuts Izagirre, Ana Sánchez Díez, Jesús María Careaga, Yoana Arroyo-Berdugo, Jesús Gardeazabal, Concepción de la Rúa
Publikováno v:
Human Heredity. 69:34-44
Background/Aim:TP53 is an efficient central node in a signal transduction network that responds to minimize cancer. However, over 50% of tumors show some mutation in TP53. Thus, one might argue that this single central node network lacks robustness.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5be5841c575e0b8e81b761fdf43154b
https://doi.org/10.1159/000243152
https://doi.org/10.1159/000243152
Autor:
Santos, Alonso, Neskuts, Izagirre, Saioa, López, Isabel, Smith-Zubiaga, Montse, Hervella, María Dolores, Boyano, Yoana, Arroyo-Berdugo, Jesús, Gardeazabal, José Luís, Díaz-Ramón, Ana, Sánchez Díez, Jesus María, Careaga, Concepción, de la Rúa
Publikováno v:
Human heredity. 69(1)
TP53 is an efficient central node in a signal transduction network that responds to minimize cancer. However, over 50% of tumors show some mutation in TP53. Thus, one might argue that this single central node network lacks robustness. Therefore, we w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b677562895f0ad84f4674d09cdfaee71
https://pubmed.ncbi.nlm.nih.gov/19797907
https://pubmed.ncbi.nlm.nih.gov/19797907
Autor:
Iker Malaina, Lorena Gonzalez-Melero, Luis Martínez, Aiala Salvador, Ana Sanchez-Diez, Aintzane Asumendi, Javier Margareto, Jose Carrasco-Pujante, Leire Legarreta, María Asunción García, Martín Blas Pérez-Pinilla, Rosa Izu, Ildefonso Martínez de la Fuente, Manoli Igartua, Santos Alonso, Rosa Maria Hernandez, María Dolores Boyano
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 10, p 9024 (2023)
In the last few years, the importance of neoantigens in the development of personalized antitumor vaccines has increased remarkably. In order to study whether bioinformatic tools are effective in detecting neoantigens that generate an immune response
Externí odkaz:
https://doaj.org/article/9eda8a8c420d4e0ca9ec9566ae3f8edd
Autor:
Filippo Mancuso, Sergio Lage, Javier Rasero, José Luis Díaz‐Ramón, Aintzane Apraiz, Gorka Pérez‐Yarza, Pilar Ariadna Ezkurra, Cristina Penas, Ana Sánchez‐Diez, María Dolores García‐Vazquez, Jesús Gardeazabal, Rosa Izu, Karmele Mujika, Jesús Cortés, Aintzane Asumendi, María Dolores Boyano
Publikováno v:
Molecular Oncology, Vol 14, Iss 8, Pp 1705-1718 (2020)
Metastasis development represents an important threat for melanoma patients, even when diagnosed at early stages and upon removal of the primary tumor. In this scenario, determination of prognostic biomarkers would be of great interest. Serum contain
Externí odkaz:
https://doaj.org/article/9611a4d808f34cc49be327fa11536b75
Autor:
Iker Malaina, Luis Martínez, Juan Manuel Montoya, Santos Alonso, María Dolores Boyano, Aintzane Asumendi, Rosa Izu, Ana Sanchez-Diez, Goikoane Cancho-Galan, Ildefonso M. de la Fuente
Publikováno v:
Life, Vol 13, Iss 1, p 155 (2023)
Background: The main purpose of this article is to introduce a universal mathematics-aided vaccine design method against malignant melanoma based on neoantigens. The universal method can be adapted to the mutanome of each patient so that a specific c
Externí odkaz:
https://doaj.org/article/c67f9c30bbdc407a854b359301d2ac7e
Autor:
Arrate Sevilla, Ana Sánchez-Diez, Sofía Cobo, Neskuts Izagirre, Conrado Martinez-Cadenas, Rosa M. Martí, Teresa Puértolas, Blanca de Unamuno, José Bañuls, Rosa Izu, Jesús Gardeazabal, Aintzane Asumendi, María D. Boyano, Santos Alonso
Publikováno v:
Life, Vol 12, Iss 12, p 2004 (2022)
Cutaneous melanoma is the most aggressive of skin tumors. In order to discover new biomarkers that could help us improve prognostic prediction in melanoma patients, we have searched for germline DNA variants associated with melanoma progression. Thus
Externí odkaz:
https://doaj.org/article/beb671702c69436996f2d46d141dfb7c
Autor:
Arrate Sevilla, M Celia Morales, Pilar A Ezkurra, Javier Rasero, Verónica Velasco, Goikoane Cancho-Galan, Ana Sánchez-Diez, Karmele Mujika, Cristina Penas, Isabel Smith, Aintzane Asumendi, Jesús M Cortés, Maria Dolores Boyano, Santos Alonso
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0230136 (2020)
Analyzing the mutational load of driver mutations in melanoma could provide valuable information regarding its progression. We aimed at analyzing the heterogeneity of mutational load of BRAF V600E in biopsies of melanoma patients of different stages,
Externí odkaz:
https://doaj.org/article/38107bb235bb4789972ed285d6e272bd
Autor:
Maider Ibarrola-Villava, Lara P Fernandez, Santos Alonso, M Dolores Boyano, Maria Peña-Chilet, Guillermo Pita, Jose A Aviles, Matias Mayor, Cristina Gomez-Fernandez, Beatriz Casado, Manuel Martin-Gonzalez, Neskuts Izagirre, Concepcion De la Rua, Aintzane Asumendi, Gorka Perez-Yarza, Yoana Arroyo-Berdugo, Enrique Boldo, Rafael Lozoya, Arantxa Torrijos-Aguilar, Ana Pitarch, Gerard Pitarch, Jose M Sanchez-Motilla, Francisca Valcuende-Cavero, Gloria Tomas-Cabedo, Gemma Perez-Pastor, Jose L Diaz-Perez, Jesus Gardeazabal, Iñigo Martinez de Lizarduy, Ana Sanchez-Diez, Carlos Valdes, Angel Pizarro, Mariano Casado, Gregorio Carretero, Rafael Botella-Estrada, Eduardo Nagore, Pablo Lazaro, Ana Lluch, Javier Benitez, Conrado Martinez-Cadenas, Gloria Ribas
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e19271 (2011)
As the incidence of Malignant Melanoma (MM) reflects an interaction between skin colour and UV exposure, variations in genes implicated in pigmentation and tanning response to UV may be associated with susceptibility to MM. In this study, 363 SNPs in
Externí odkaz:
https://doaj.org/article/54eddd4350a44dff8928703af2a4810d