Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Ana Rodríguez-Galán"'
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 1, p 250 (2022)
MicroRNAs (miRNAs) act as master regulators of gene expression in homeostasis and disease. Despite the rapidly growing body of evidence on the theranostic potential of restoring miRNA levels in pre-clinical models, the translation into clinics remain
Externí odkaz:
https://doaj.org/article/6c2b4cb928cc4885b23b80799b55b8e6
Autor:
Ana Rodríguez-Galán, Sara G. Dosil, Manuel José Gómez, Irene Fernández-Delgado, Lola Fernández-Messina, Fátima Sánchez-Cabo, Francisco Sánchez-Madrid
Publikováno v:
iScience, Vol 24, Iss 6, Pp 102530- (2021)
Summary: T cell activation leads to extensive changes in the miRNA repertoire. Although overall miRNA expression decreases within a few hours of T cell activation, some individual miRNAs are specifically upregulated. Using next-generation sequencing,
Externí odkaz:
https://doaj.org/article/ce71d33f8e284321a6106de0bc2b61a9
Autor:
Cristina Gutiérrez-Vázquez, Ana Rodríguez-Galán, Marcos Fernández-Alfara, María Mittelbrunn, Fátima Sánchez-Cabo, Dannys Jorge Martínez-Herrera, Marta Ramírez-Huesca, Alberto Pascual-Montano, Francisco Sánchez-Madrid
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Abstract microRNAs (miRNAs) are tightly regulated during T lymphocyte activation to enable the establishment of precise immune responses. Here, we analyzed the changes of the miRNA profiles of T cells in response to activation by cognate interaction
Externí odkaz:
https://doaj.org/article/c2274d1f5a744b7cac98049a132aa4fe
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
MiRNA targeting of key immunoregulatory molecules fine-tunes the immune response. This mechanism boosts or dampens immune functions to preserve homeostasis while supporting the full development of effector functions. MiRNA expression changes during T
Externí odkaz:
https://doaj.org/article/51bbb49f73a948138f873faeb098a772
Autor:
Francisco Sánchez-Madrid, Irene Fernández-Delgado, Raquel Castillo-González, Raúl Izquierdo-Serrano, Elena Moya-Ruiz, Marta Ramírez-Huesca, Olga Moreno-Gonzalo, Ana Rodríguez-Galán, Nieves Fernández-Gallego Anaya, Alberto Fernández-Bernaldez, Javier Sanchez-Perez, Danay Cibrian, Hortensia de la Fuente, Susana Guerra
The role of ISG15 (Interferon-Stimulated Gene 15) is becoming increasingly acknowledged in cancer, pathogen infection and inflammatory immune diseases. ISG15 expression increases in human psoriatic skin, and genetic mutations of ISG15 cause dermatolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c897636a01acec6d90861e53307d50cf
https://doi.org/10.22541/au.166911170.08332363/v1
https://doi.org/10.22541/au.166911170.08332363/v1
Autor:
Manuel Gómez, Fátima Sánchez-Cabo, Francisco Sánchez-Madrid, Irene Fernández-Delgado, Sara G. Dosil, Lola Fernández-Messina, Ana Rodríguez-Galán
Publikováno v:
iScience, Vol 24, Iss 6, Pp 102530-(2021)
iScience
iScience
Summary T cell activation leads to extensive changes in the miRNA repertoire. Although overall miRNA expression decreases within a few hours of T cell activation, some individual miRNAs are specifically upregulated. Using next-generation sequencing,
Autor:
Francisco Sánchez-Madrid, Manuel Gómez, Fátima Sánchez-Cabo, Sara G. Dosil, Ana Rodríguez-Galán, Irene Fernández-Delgado
MiRNA repertoire of T cells undergoes extensive changes in response to activation. Whereas global miRNA downregulation occurs few hours after activation, some individual miRNAs are specifically up- or down-regulated. In this study, we have assessed m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d738e8541a530294b38f81551592c9d
https://doi.org/10.1101/2020.08.19.257816
https://doi.org/10.1101/2020.08.19.257816
Transfer of extracellular vesicle‐microRNA controls germinal center reaction and antibody production
Autor:
Virginia G. de Yébenes, Sandra Tenreiro, Francisco Sánchez-Madrid, Almudena R. Ramiro, Miguel C. Seabra, Lola Fernández-Messina, Cristina Gutiérrez-Vázquez, Ana Rodríguez-Galán
Publikováno v:
EMBO Reports
Repisalud
Instituto de Salud Carlos III (ISCIII)
Repisalud
Instituto de Salud Carlos III (ISCIII)
Intercellular communication orchestrates effective immune responses against disease‐causing agents. Extracellular vesicles (EVs) are potent mediators of cell–cell communication. EVs carry bioactive molecules, including microRNAs, which modulate g
Autor:
Chris J. Janse, Marta Ulaszewska, Ana Rodríguez-Galán, Julius C. R. Hafalla, Alexandra J. Spencer, Ahmed M. Salman, Katie J. Ewer, Georgina Bowyer, Florian Brod, Adrian V. S. Hill, Katharine A. Collins, Shahid M. Khan, Rhea J. Longley
Publikováno v:
Scientific Reports, 7
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
A large research effort is currently underway to find an effective and affordable malaria vaccine. Tools that enable the rapid evaluation of protective immune responses are essential to vaccine development as they can provide selection criteria to ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7efa0a12011e2fc5911772ec6e3a9db3
https://hdl.handle.net/1887/115820
https://hdl.handle.net/1887/115820
Autor:
Marcos Fernández-Alfara, Fátima Sánchez-Cabo, Ana Rodríguez-Galán, Marta Ramírez-Huesca, Francisco Sánchez-Madrid, Cristina Gutiérrez-Vázquez, Dannys Jorge Martinez-Herrera, Alberto Pascual-Montano, María Mittelbrunn
Publikováno v:
Repisalud
Instituto de Salud Carlos III (ISCIII)
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Biblos-e Archivo. Repositorio Institucional de la UAM
instname
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Scientific Reports
Instituto de Salud Carlos III (ISCIII)
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Biblos-e Archivo. Repositorio Institucional de la UAM
instname
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Scientific Reports
microRNAs (miRNAs) are tightly regulated during T lymphocyte activation to enable the establishment of precise immune responses. Here, we analyzed the changes of the miRNA profiles of T cells in response to activation by cognate interaction with dend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1e7ee3ffa0858789297d7892a05f5c8
https://doi.org/10.1038/s41598-017-03689-7
https://doi.org/10.1038/s41598-017-03689-7