Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Ana Rastija"'
Autor:
Kristina Dominko, Ana Rastija, Sandra Sobocanec, Lea Vidatic, Sarah Meglaj, Andrea Lovincic Babic, Birgit Hutter-Paier, Alessio-Vittorio Colombo, Stefan F. Lichtenthaler, Sabina Tahirovic, Silva Hecimovic
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 24, p 13256 (2021)
Niemann-Pick type C disease (NPC) is a rare inherited neurodegenerative disorder characterized by an accumulation of intracellular cholesterol within late endosomes and lysosomes due to NPC1 or NPC2 dysfunction. In this work, we tested the hypothesis
Externí odkaz:
https://doaj.org/article/67ca3503d20b48539006972a0277bafd
Autor:
Kristina Dominko, Ana Rastija, Kosara Smiljanic, Aleksandra Mladenovic, Lucija Lešnjaković, Selma Kanazir, Desanka Milanovic, Silva Hecimovic
Publikováno v:
Mechanisms of Ageing and Development
The formation of amyloid-ß peptides (Aß), that accumulate in Alzheimer's disease (AD) brains, involves proteolytic processing of the amyloid precursor protein (APP) firstly by ß-secretase (BACE1). Since BACE1 cleaves a plethora of other substrates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40b101dd6cf3005ba464cf75b12f866e
http://fulir.irb.hr/7675/7/MAD-D-22-00218_R1.pdf
http://fulir.irb.hr/7675/7/MAD-D-22-00218_R1.pdf