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Akademický článek

Neurotoxic Astrocytes Directly Converted from Sporadic and Familial ALS Patient Fibroblasts Reveal Signature Diversities and miR-146a Theragnostic Potential in Specific Subtypes

Autor: Cátia Gomes, Catarina Sequeira, Shibi Likhite, Cassandra N. Dennys, Stephen J. Kolb, Pamela J. Shaw, Ana R. Vaz, Brian K. Kaspar, Kathrin Meyer, Dora Brites

Publikováno v: Cells, Vol 11, Iss 7, p 1186 (2022)

A lack of stratification methods in patients with amyotrophic lateral sclerosis (ALS) is likely implicated in therapeutic failures. Regional diversities and pathophysiological abnormalities in astrocytes from mice with SOD1 mutations (mSOD1-ALS) can

Externí odkaz: https://doaj.org/article/b22c77976eb9481a93281f8a06e61364

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Akademický článek

Key Aging-Associated Alterations in Primary Microglia Response to Beta-Amyloid Stimulation

Autor: Cláudia Caldeira, Carolina Cunha, Ana R. Vaz, Ana S. Falcão, Andreia Barateiro, Elsa Seixas, Adelaide Fernandes, Dora Brites

Publikováno v: Frontiers in Aging Neuroscience, Vol 9 (2017)

Alzheimer’s disease (AD) is characterized by a progressive cognitive decline and believed to be driven by the self-aggregation of amyloid-β (Aβ) peptide into oligomers and fibrils that accumulate as senile plaques. It is widely accepted that micr

Externí odkaz: https://doaj.org/article/2a58334d6c5548b3a28ff880132956b9

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Akademický článek

Exosomes from NSC-34 Cells Transfected with hSOD1-G93A Are Enriched in miR-124 and Drive Alterations in Microglia Phenotype

Autor: Sara Pinto, Carolina Cunha, Marta Barbosa, Ana R. Vaz, Dora Brites

Publikováno v: Frontiers in Neuroscience, Vol 11 (2017)

Amyotrophic lateral sclerosis (ALS) is a fatal adult-onset neurodegenerative disorder affecting motor neurons (MNs). Evidences indicate that ALS is a non-cell autonomous disease in which glial cells participate in both disease onset and progression.

Externí odkaz: https://doaj.org/article/2cbbd745d75e47ad86d251ceb8ba9711

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Akademický článek

Features of bilirubin-induced reactive microglia: From phagocytosis to inflammation

Autor: Sandra L. Silva, Ana R. Vaz, Andreia Barateiro, Ana S. Falcão, Adelaide Fernandes, Maria A. Brito, Rui F.M. Silva, Dora Brites

Publikováno v: Neurobiology of Disease, Vol 40, Iss 3, Pp 663-675 (2010)

Microglia constitute the brain's immunocompetent cells and are intricately implicated in numerous inflammatory processes included in neonatal brain injury. In addition, clearance of tissue debris by microglia is essential for tissue homeostasis and m

Externí odkaz: https://doaj.org/article/fb5f1f604e9e4456904c9dab92e7902a

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The factorial structure and psychometric properties of the Committed Action Questionnaire (CAQ‐8) in a Portuguese clinical sample with eating disorders

Autor: Fernando Fernández-Aranda, Patrícia Nunes, Tânia Rodrigues, Isabel Brandão, Ana Isabel Vieira, Sertório Timóteo, Paulo P. P. Machado, Ana R. Vaz

Publikováno v: Clinical Psychology & Psychotherapy. 29:222-229

The Committed Action Questionnaire (CAQ-8) is an instrument developed to measure committed action, an adaptive psychological process. The main goal in the current study was to confirm the factorial structure of the Portuguese version of the CAQ-8 in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba4dff4fe7deb5727cc5005c8798f037
https://doi.org/10.1002/cpp.2621

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Impact of COVID-19 lockdown measures on a cohort of eating disorders patients

Autor: Isabel Brandão, Ana Pinto-Bastos, Tânia Rodrigues, Sónia Gonçalves, Ana R. Vaz, Elsa Louro, Rita Ramos, Paulo P. P. Machado

Publikováno v: Journal of Eating Disorders, Vol 8, Iss 1, Pp 1-8 (2020)
Journal of Eating Disorders
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

BackgroundLockdown implemented to prevent the COVID-19 spread resulted in marked changes in the lifestyle. The objective of the current study was to assess the impact of lockdown measures on a cohort of eating disorder (ED) patients being followed as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7def951087c60e8fb02475199a09efbd
http://link.springer.com/article/10.1186/s40337-020-00340-1

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The utility of DSM‐5 indicators of loss of control eating for the bariatric surgery population

Autor: Ana Pinto-Bastos, Ana R. Vaz, Marta de Lourdes, Andrea B. Goldschmidt, Ana Paula Pereira Peixoto, Eva Conceição

Publikováno v: Eur Eat Disord Rev

OBJECTIVES This study investigated the utility of DSM-5 indicators of loss of control (LOC) eating in adult bariatric surgery patients who presented with binge-eating episodes. METHODS Participants (all women) were 40 preoperative and 28 postoperativ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61e72a3b17463d478f79ace8580b03ba
https://doi.org/10.1002/erv.2737

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The impact of COVID-19 lockdown on disordered eating behaviors: the mediation role of psychological distress

Autor: Eva Conceição, Sofia Ramalho, Paulo P. P. Machado, Sónia Gonçalves, Ana Trovisqueira, Inês Ribeiro, Ana R. Vaz, Marta de Lourdes

Publikováno v: Eating and Weight Disorders

Purpose: This study aimed to explore the early associations between the experienced psychosocial impact of the COVID-19 pandemic crisis during lockdown, depressive symptomatology, anxiety/stress levels, and disordered eating behaviors in adults durin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::383af245ebfc26df437e1810bbc94605
https://hdl.handle.net/1822/79296

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Eating Disorder‐15 (ED‐15): Factor structure, psychometric properties, and clinical validation

Autor: Tânia Rodrigues, Cátia Silva, Eva Conceição, Ana R. Vaz, Paulo P. P. Machado

Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

Objective The purpose of the current study was to explore the factor structure and psychometric properties of the Portuguese version of the Eating Disorder-15 (ED-15), as well as to establish cutoff scores and normative data for the Portuguese versio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caabed9b3ead725e0a0c1a3c4e1ddc8d
https://doi.org/10.1002/erv.2694

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Perceived social support before and after bariatric surgery: association with depression, problematic eating behaviors, and weight outcomes

Autor: Marta Fernandes, Sofia Ramalho, Marta de Lourdes, Ana R. Vaz, Eva Conceição, Ana Pinto-Bastos

Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

Purpose Engaging in a healthy lifestyle after bariatric surgery is essential to optimize and sustain weight loss in the long term. There is promising evidence that social support of patients who undergo bariatric surgery plays an important role in pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbcf2dc97c29be45823bc7b7b8c53271
https://doi.org/10.1007/s40519-019-00671-2

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