Výsledky vyhledávání - "Ana R. Coelho"

Akademický článek

Large nodule in the shoulder of an elderly woman

Autor: Patrícia Amoedo, Pedro Matos, Ana R. Coelho, Maria J. Cruz

Publikováno v: Revista da Sociedade Portuguesa de Dermatologia e Venereologia, Vol 82, Iss 3 (2024)

Externí odkaz: https://doaj.org/article/eee61b94565245e5956e8693d277d9be

Akademický článek

Radiation Therapy Skin Marking with Lancets Versus Electric Marking Pen (COMFORTATTOO)—6 Months Results on Cosmesis, Fading, and Patients’ Satisfaction From a Randomized, Double-Blind Trial

Autor: André M. Pires, MD, Luísa Carvalho, MD, Ana C. Santos, BsC, Ana M. Vilaça, BsC, Ana R. Coelho, MsC, Celeste Oliveira, MsC, Céline Costa, MsC, Flávia Fernandes, MD, Liliana Moreira, BsC, João Lima, MD, Rafaela Vieira, BsC, Maria J. Ferraz, BsC, Marta Silva, BsC, Pedro Silva, MsC, Rafael Matias, MD, Sara Zorro, MD, Susana Costa, PhD, Susana Sarandão, MD, Ana F. Barros, BsC

Publikováno v: Advances in Radiation Oncology, Vol 9, Iss 3, Pp 101404- (2024)

Purpose: Most of radiation oncology centers rely on set-up skin markings for patient setup during treatment delivery. Permanent dark-ink tattooing is the most popular marking method. COMFORTATTOO is a unicentric, randomized trial testing 2 permanent

Externí odkaz: https://doaj.org/article/3b47186c74424426926d613462b6323c

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Akademický článek

Inhibition-based biosensor for cyanide detection – a preliminary study

Autor: Ana R. Coelho, Tiago Monteiro, Ana S. Viana, M. Gabriela Almeida

Publikováno v: Annals of Medicine, Vol 53, Iss sup1, Pp S41-S42 (2021)

AbstractIntroduction The acute toxicity of cyanide along with its continue industrial use makes this substance of environmental concern [1]. Titration, spectrophotometry and ISE are the standard detection methods. However, they are complex and need s

Externí odkaz: https://doaj.org/article/e577dd39c9d3416e940e1ffc34aca3ee

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A Selective SARS-CoV-2 Host-Directed Antiviral Targeting Stress Response to Reactive Oxygen Species

Autor: Cong Tang, Ana R. Coelho, Maria Rebelo, Hannah Kiely-Collins, Tânia Carvalho, Gonçalo J. L. Bernardes

The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) catalyzed the development of vaccines and antivirals. Clinically approved drugs against SARS-CoV-2 target the virus directly, which makes them susceptible to viral mutation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2783a69413d8e3200d428c63d3531571

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Akademický článek

Horizontal transfer of whole mitochondria restores tumorigenic potential in mitochondrial DNA-deficient cancer cells

Publikováno v: eLife, Vol 6 (2017)

Recently, we showed that generation of tumours in syngeneic mice by cells devoid of mitochondrial (mt) DNA (ρ0 cells) is linked to the acquisition of the host mtDNA. However, the mechanism of mtDNA movement between cells remains unresolved. To deter

Externí odkaz: https://doaj.org/article/4285105d6a3d4ae5a57e35604fc4c03d

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Replication and ribosomal stress induced by targeting pyrimidine synthesis and cellular checkpoints suppress p53-deficient tumors

Autor: Jaromira Kovarova, Jakub Rohlena, Jiri Neuzil, Sona Hubackova, Martina Bajzikova, Henrik J. Ditzel, Eliska Davidova, Ana R Coelho, Mikkel G. Terp, Stepana Boukalova

Publikováno v: Cell Death and Disease, Vol 11, Iss 2, Pp 1-16 (2020)
Cell Death & Disease
Hubackova, S, Davidova, E, Boukalova, S, Kovarova, J, Bajzikova, M, Coelho, A, Terp, M G, Ditzel, H J, Rohlena, J & Neuzil, J 2020, ' Replication and ribosomal stress induced by targeting pyrimidine synthesis and cellular checkpoints suppress p53-deficient tumors ', Cell Death and Disease, vol. 11, no. 2, 110 . https://doi.org/10.1038/s41419-020-2224-7

p53-mutated tumors often exhibit increased resistance to standard chemotherapy and enhanced metastatic potential. Here we demonstrate that inhibition of dihydroorotate dehydrogenase (DHODH), a key enzyme of the de novo pyrimidine synthesis pathway, e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee64df7d1fe4ff6bdcba16ce4b92275c
http://link.springer.com/article/10.1038/s41419-020-2224-7

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MOTS-c reduces myostatin and muscle atrophy signaling

Autor: Paulo J. Oliveira, Ana R Coelho, Hirofumi Zempo, Kelvin Yen, Pinchas Cohen, Noriyuki Fuku, Hemal H. Mehta, Amy Huang, Hiroshi Kumagai, Junxiang Wan, Su-Jeong Kim, Seiji Maeda

Publikováno v: Am J Physiol Endocrinol Metab

Obesity and type 2 diabetes are metabolic diseases, often associated with sarcopenia and muscle dysfunction. MOTS-c, a mitochondrial-derived peptide, acts as a systemic hormone and has been implicated in metabolic homeostasis. Although MOTS-c improve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18c69590a7987fb339f1196d186ac9cc
https://pubmed.ncbi.nlm.nih.gov/33554779

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Cancer cell metabolism: Rewiring the mitochondrial hub

Autor: Ricardo Marques, Paulo J. Oliveira, Ana R Coelho, Gabriela L. Oliveira

Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

To adapt to tumoral environment conditions or even to escape chemotherapy, cells rapidly reprogram their metabolism to handle adversities and survive. Given the rapid rise of studies uncovering novel insights and therapeutic opportunities based on th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb88dbad3a6ab3dbc24cb34579d9cb2e
https://pubmed.ncbi.nlm.nih.gov/33246010

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