Zobrazeno 1 - 10
of 126
pro vyhledávání: '"Ana R. Quesada"'
Autor:
Mª Carmen Ocaña, Manuel Bernal, Chendong Yang, Carlos Caro, Alejandro Domínguez, Hieu S. Vu, Casimiro Cárdenas, María Luisa García-Martín, Ralph J. DeBerardinis, Ana R. Quesada, Beatriz Martínez-Poveda, Miguel Ángel Medina
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-14 (2023)
Abstract Dimethyl fumarate is an ester from the Krebs cycle intermediate fumarate. This drug is approved and currently used for the treatment of psoriasis and multiple sclerosis, and its anti-angiogenic activity was reported some years ago. Due to th
Externí odkaz:
https://doaj.org/article/57c54807cba84dffbefcaccfa81faf2a
Autor:
Imane Allali-Boumara, Ana Dácil Marrero, Ana R. Quesada, Beatriz Martínez-Poveda, Miguel Ángel Medina
Publikováno v:
Antioxidants, Vol 12, Iss 8, p 1551 (2023)
Pyroptosis is an inflammation-dependent type of cell death that has been in the spotlight for the scientific community in the last few years. Crucial players in the process of pyroptosis are the members of the gasdermin family of proteins, which have
Externí odkaz:
https://doaj.org/article/1ff18bced49f4e5e9da1a1421630510a
Autor:
Ana Dácil Marrero, Laura Castilla, Manuel Bernal, Inmaculada Manrique, Joel D. Posligua-García, Federico Moya-Utrera, Cristina Porras-Alcalá, José Luis Espartero, Francisco Sarabia, Ana R. Quesada, Miguel Ángel Medina, Beatriz Martínez-Poveda
Publikováno v:
Antioxidants, Vol 12, Iss 8, p 1513 (2023)
Hydroxytyrosol (HT) is a bioactive phenolic compound naturally present in olives and extra virgin olive oil (EVOO) which is described as an antioxidant, antitumoral and antiangiogenic molecule. Previous studies of semi-synthetic HT-derivatives presen
Externí odkaz:
https://doaj.org/article/3e3efff06ddf45d9b53d009aa9da91e9
Autor:
Isabel Vidal, José Antonio Torres-Vargas, José María Sánchez, Mónica Trigal, Melissa García-Caballero, Miguel Ángel Medina, Ana R. Quesada
Publikováno v:
Antioxidants, Vol 12, Iss 5, p 1101 (2023)
The role played by a sustained angiogenesis in cancer and other diseases stimulates the interest in the search for new antiangiogenic drugs. In this manuscript, we provide evidence that 1,8- dihydroxy-9,10-anthraquinone (danthron), isolated from the
Externí odkaz:
https://doaj.org/article/f832f64f89914aaba6192ebe70097b91
Autor:
Isabel Vidal, Laura Castilla, Ana Dácil Marrero, Inés Bravo-Ruiz, Manuel Bernal, Inmaculada Manrique, Ana R. Quesada, Miguel Ángel Medina, Beatriz Martínez-Poveda
Publikováno v:
Marine Drugs, Vol 20, Iss 10, p 605 (2022)
(+)-Aeroplysinin-1 (Apl-1) is a brominated compound isolated from the marine sponge Aplysina aerophoba that exhibits pleiotropic bioactive effects, impairing cell growth in cancer cells, inhibiting angiogenesis in vitro and in vivo and modulating the
Externí odkaz:
https://doaj.org/article/705f6999d5d2466495144f508d22baf0
Publikováno v:
Antioxidants, Vol 11, Iss 2, p 302 (2022)
Despite the extensive knowledge on cancer nature acquired over the last years, the high incidence of this disease evidences a need for new approaches that complement the clinical intervention of tumors. Interestingly, many types of cancer are closely
Externí odkaz:
https://doaj.org/article/2ee151f9c4074e9abd8e4f19b0257ff8
Autor:
Melissa García-Caballero, José Antonio Torres-Vargas, Ana Dácil Marrero, Beatriz Martínez-Poveda, Miguel Ángel Medina, Ana R. Quesada
Publikováno v:
Pharmaceutics, Vol 14, Iss 2, p 256 (2022)
The number of cancer cases worldwide keeps growing unstoppably, despite the undeniable advances achieved by basic research and clinical practice. Urologic tumors, including some as prevalent as prostate, bladder or kidney tumors, are no exceptions to
Externí odkaz:
https://doaj.org/article/23358f45db5949a5bdfcad23bd9d0b76
Publikováno v:
Biology, Vol 9, Iss 1, p 16 (2020)
Metabolic reprogramming in tumor cells is considered one of the hallmarks of cancer. Many studies have been carried out in order to elucidate the effects of tumor cell metabolism on invasion and tumor progression. However, little is known about the i
Externí odkaz:
https://doaj.org/article/994b47f567bf44e79ecbc83a1b47b5b9
Autor:
Paloma Carrillo, Melissa García-Caballero, Manuel Bernal, María Inmaculada Manrique-Poyato, Beatriz Martínez-Poveda, Ana R. Quesada, Miguel Ángel Medina
Publikováno v:
Matrix Pathobiology and Angiogenesis ISBN: 9783031196157
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b7ff783460adbd37389d0090e56b9de
https://doi.org/10.1007/978-3-031-19616-4_6
https://doi.org/10.1007/978-3-031-19616-4_6
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
Evasion of apoptosis is a hallmark of cancer especially relevant in the development and the appearance of leukemia drug resistance mechanisms. The development of new drugs that could trigger apoptosis in aggressive hematological malignancies, such as
Externí odkaz:
https://doaj.org/article/4628e62265cc46d9a0c0604d24f6cfa9