Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Ana Ponces, Freire"'
Autor:
Gonçalo da Costa, Cristina Ribeiro-Silva, Raquel Ribeiro, Samuel Gilberto, Ricardo A Gomes, António Ferreira, Élia Mateus, Eduardo Barroso, Ana V Coelho, Ana Ponces Freire, Carlos Cordeiro
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0125392 (2015)
Transthyretin amyloidosis is a conformational pathology characterized by the extracellular formation of amyloid deposits and the progressive impairment of the peripheral nervous system. Point mutations in this tetrameric plasma protein decrease its s
Externí odkaz:
https://doaj.org/article/106c2bbc25cd438fb955ea5bf82f2744
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e32749 (2012)
Systems biology relies heavily on the construction of quantitative models of biochemical networks. These models must have predictive power to help unveiling the underlying molecular mechanisms of cellular physiology, but it is also paramount that the
Externí odkaz:
https://doaj.org/article/b1f210b995d34775a2ccc8d476c4ce56
Autor:
Ricardo A Gomes, Catarina Franco, Gonçalo Da Costa, Sébastien Planchon, Jenny Renaut, Raquel M Ribeiro, Francisco Pinto, Marta Sousa Silva, Ana Varela Coelho, Ana Ponces Freire, Carlos Cordeiro
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e50123 (2012)
Protein misfolding disorders such as Alzheimer, Parkinson and transthyretin amyloidosis are characterized by the formation of protein amyloid deposits. Although the nature and location of the aggregated proteins varies between different diseases, the
Externí odkaz:
https://doaj.org/article/06d0da94b6fc4fb8a49474731c7a5355
Autor:
Gonçalo da Costa, Ricardo A Gomes, Ana Guerreiro, Élia Mateus, Estela Monteiro, Eduardo Barroso, Ana V Coelho, Ana Ponces Freire, Carlos Cordeiro
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e24850 (2011)
Familial amyloidotic polyneuropathy (FAP) is a systemic conformational disease characterized by extracellular amyloid fibril formation from plasma transthyretin (TTR). This is a crippling, fatal disease for which liver transplantation is the only eff
Externí odkaz:
https://doaj.org/article/26a8cc39dd2c4a0caded00fa6866d7ce
Autor:
Diana G. Ferreira, Wei Xiang, Hugo Vicente Miranda, Nuno C. Santos, Luís M. A. Oliveira, Irina Zamolo, Deborah Penque, Olaf Riess, Ruth Rott, Flaviano Giorgini, Carlos Cordeiro, Márcia Oliveira, Marcos António Gomes, Ekrem Darendelioglu, Luísa V. Lopes, Tiago F. Outeiro, Carlo Breda, Alexandre Quintas, Eva F. Rodrigues, Éva M. Szegő, Markus Zweckstetter, Hilal A. Lashuel, Michael Heinrich, Tânia Simões, Rita Oliveira, Ivo C. Martins, Thomas M. Jovin, Francisco J. Enguita, Jochen Klucken, Francesca Munari, Simone Engelender, Ana Ponces-Freire
Publikováno v:
Brain. 144:e58-e58
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d077490bfec4c3dbccdabf2eec5c446
https://doi.org/10.1093/brain/awab175
https://doi.org/10.1093/brain/awab175
Autor:
Filipa Monteiro, Mónica Sebastiana, António E. N. Ferreira, Ana Patrícia Marques, Marta Sousa Silva, Ana Ponces Freire, Marisa Maia, Andreia Figueiredo, Carlos Cordeiro
Publikováno v:
EuPA Open Proteomics
Graphical abstract Improved and efficient metabolite extraction method for maximizing the number of metabolites identified from a single biological sample, compatible with DI-FTICR-MS-based metabolomics.
Highlights • An improved metabolite ext
Highlights • An improved metabolite ext
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::863c747642971d28f45f540c7514929d
https://doi.org/10.1016/j.euprot.2016.03.002
https://doi.org/10.1016/j.euprot.2016.03.002
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Raising awareness about sustainability is an urgent need and as such education for sustainability has gained relevancy for the last decades. It is acknowledged that science education can work as an important context for educating for sustainability.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24f1f0ec4d429d1fadc29653a81cdeab
https://doi.org/10.13189/ujer.2016.040803
https://doi.org/10.13189/ujer.2016.040803
Autor:
António E. N. Ferreira, Marta Sousa Silva, Ana Patrícia Marques, Ana Ponces Freire, Carlos Cordeiro, Maria Luísa Serralheiro
Publikováno v:
Biochemistry and Molecular Biology Education. 44:38-54
Metabolomics is a key discipline in systems biology, together with genomics, transcriptomics, and proteomics. In this omics cascade, the metabolome represents the biochemical products that arise from cellular processes and is often regarded as the fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70301d2b750e4df25791c6e9889dadfa
https://doi.org/10.1002/bmb.20919
https://doi.org/10.1002/bmb.20919
Autor:
Carlos Cordeiro, Luís M. A. Oliveira, Ruth Rott, Deborah Penque, Tania Simões, Michael Heinrich, Francesca Munari, Ekrem Darendelioglu, Olaf Riess, Carlo Breda, Diana G. Ferreira, Thomas M. Jovin, Rita Machado de Oliveira, Luísa V. Lopes, Eva F. Rodrigues, Ivo C. Martins, Hugo Vicente Miranda, Jochen Klucken, Markus Zweckstetter, Hilal A. Lashuel, Alexandre Quintas, Márcia Oliveira, Nuno C. Santos, Marcos António Gomes, Tiago F. Outeiro, Irina Zamolo, Wei Xiang, Simone Engelender, Ana Ponces-Freire, Francisco J. Enguita, Éva M. Szegö, Flaviano Giorgini
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Agência para a Sociedade do Conhecimento (UMIC)-FCT-Sociedade da Informação
instacron:RCAAP
Brain
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
Brain 140(5), 1399-1419 (2017). doi:10.1093/brain/awx056
Agência para a Sociedade do Conhecimento (UMIC)-FCT-Sociedade da Informação
instacron:RCAAP
Brain
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
Brain 140(5), 1399-1419 (2017). doi:10.1093/brain/awx056
© The Author (2017). Published by Oxford University Press on behalf of the Guarantors of Brain. All rights reserved.
α-Synuclein misfolding and aggregation is a hallmark in Parkinson's disease and in several other neurodegenerative diseases kn
α-Synuclein misfolding and aggregation is a hallmark in Parkinson's disease and in several other neurodegenerative diseases kn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d50ba62720be24e704cb583505996af7
Publikováno v:
Biochemical Journal. 453:1-15
The discovery of the enzymatic formation of lactic acid from methylglyoxal dates back to 1913 and was believed to be associated with one enzyme termed ketonaldehydemutase or glyoxalase, the latter designation prevailed. However, in 1951 it was shown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93f3136eb3b927c580a62a8ac57b8c5b
https://doi.org/10.1042/bj20121743
https://doi.org/10.1042/bj20121743