Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Ana Podolski-Renić"'
Autor:
Jelena Dinić, Sofija Jovanović Stojanov, Miodrag Dragoj, Marija Grozdanić, Ana Podolski-Renić, Milica Pešić
Publikováno v:
Life, Vol 14, Iss 9, p 1142 (2024)
The field of oncology has witnessed remarkable progress in personalized cancer therapy. Functional precision medicine has emerged as a promising avenue for achieving superior treatment outcomes by integrating omics profiling and sensitivity testing o
Externí odkaz:
https://doaj.org/article/56e2025699b04560acc69597f2f68d40
Publikováno v:
Molecules, Vol 29, Iss 18, p 4308 (2024)
Our review paper evaluates the impact of plant-based products, primarily derived from plants from Serbia, on P-glycoprotein (P-gp) activity and their potential in modulating drug resistance in cancer therapy. We focus on the role and regulation of P-
Externí odkaz:
https://doaj.org/article/599099b845dd4119b482bb4cdf0fd933
Autor:
Jelena Dinić, Ana Podolski-Renić, Miodrag Dragoj, Sofija Jovanović Stojanov, Ana Stepanović, Ema Lupšić, Milica Pajović, Mirna Jovanović, Dušica Petrović Rodić, Dragana Marić, Maja Ercegovac, Milica Pešić
Publikováno v:
Diagnostics, Vol 13, Iss 24, p 3617 (2023)
Lung cancer remains the leading cause of cancer death globally, with non-small cell lung cancer (NSCLC) accounting for the majority of cases. Multidrug resistance (MDR), often caused by ATP-binding cassette (ABC) transporters, represents a significan
Externí odkaz:
https://doaj.org/article/db08c6ecaea04e3b8de6101fc3e2f20a
Autor:
Milka Jadranin, Danica Savić, Ema Lupšić, Ana Podolski-Renić, Milica Pešić, Vele Tešević, Slobodan Milosavljević, Gordana Krstić
Publikováno v:
Plants, Vol 12, Iss 24, p 4181 (2023)
Euphorbia seguieriana ssp. seguieriana Necker (ES) and Euphorbia cyparissias (EC) with a habitat in the Deliblato Sands were the subject of this examination. The latexes of these so far insufficiently investigated species of the Euphorbia genus are u
Externí odkaz:
https://doaj.org/article/1d73ce0ed88f4ed8aa8cd953087567af
Autor:
Sofija Jovanović Stojanov, Epole N. Ntungwe, Jelena Dinić, Ana Podolski-Renić, Milica Pajović, Patrícia Rijo, Milica Pešić
Publikováno v:
Pharmaceutics, Vol 15, Iss 7, p 1942 (2023)
Multidrug resistance in cancer is often mediated by P-glycoprotein. Natural compounds have been suggested as a fourth generation of P-glycoprotein inhibitors. Coleon U, isolated from Plectranthus mutabilis Codd., was reported to modulate P-glycoprote
Externí odkaz:
https://doaj.org/article/02b78a466b5143bb847c68ec8f23bd99
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
The intracellular redox homeostasis is a dynamic balancing system between the levels of free radical species and antioxidant enzymes and small molecules at the core of cellular defense mechanisms. The thioredoxin (Trx) system is an important detoxifi
Externí odkaz:
https://doaj.org/article/685d5339d4ba4765a62deffdda27ca5e
Autor:
Olga Bakulina, Anton Bannykh, Mirna Jovanović, Ilona Domračeva, Ana Podolski-Renić, Raivis Žalubovskis, Milica Pešić, Dmitry Dar’in, Mikhail Krasavin
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 665-671 (2019)
Human thioredoxin reductase 1 (TrxR1) is a selenocysteine-containing enzyme which plays a crucial role in regulating numerous redox signalling pathways within the cell. While its functioning is important in all cells, levels of TrxR1 expression are h
Externí odkaz:
https://doaj.org/article/56ccb2a5330943a7acddac380ac74b62
Autor:
Mirna Jovanović, Miodrag Dragoj, Daniil Zhukovsky, Dmitry Dar’in, Mikhail Krasavin, Milica Pešić, Ana Podolski-Renić
Publikováno v:
Frontiers in Molecular Biosciences, Vol 7 (2020)
Currently, available glioblastoma (GBM) treatment remains ineffective, with relapse after initial response and low survival rate of GBM patients. The reasons behind limited capacities for GBM treatment are high tumor heterogeneity, invasiveness, and
Externí odkaz:
https://doaj.org/article/825a0bd67b4844f7a7299bcdf32a81dd
Autor:
Miodrag Dragoj, Jasmina Stojkovska, Tijana Stanković, Jelena Dinić, Ana Podolski-Renić, Bojana Obradović, Milica Pešić
Publikováno v:
Brain Sciences, Vol 11, Iss 8, p 1025 (2021)
Background: Various three-dimensional (3D) glioblastoma cell culture models have a limited duration of viability. Our aim was to develop a long-term 3D glioblastoma model, which is necessary for reliable drug response studies. Methods: Human U87 glio
Externí odkaz:
https://doaj.org/article/6daea0b63a8b40acbee63bce22cb1f30
Autor:
Ana Kostić, Sofija Jovanović Stojanov, Ana Podolski-Renić, Marija Nešović, Miodrag Dragoj, Igor Nikolić, Goran Tasić, Silvia Schenone, Milica Pešić, Jelena Dinić
Publikováno v:
Brain Sciences, Vol 11, Iss 7, p 884 (2021)
Background: Glioblastoma (GBM) highly expresses Src tyrosine kinase involved in survival, proliferation, angiogenesis and invasiveness of tumor cells. Src activation also reduces reactive oxygen species (ROS) generation, whereas Src inhibitors are ab
Externí odkaz:
https://doaj.org/article/8b53cf626efb4386967a50026a3d49d8