Aqueous extract from Mangifera indica Linn. (Anacardiaceae) leaves exerts long-term hypoglycemic effect, increases insulin sensitivity and plasma insulin levels on diabetic Wistar rats.

Autor: Gustavo Roberto Villas Boas, João Marcos Rodrigues Lemos, Matheus William de Oliveira, Rafael Claudino Dos Santos, Ana Paula Stefanello da Silveira, Flávia Barbieri Bacha, Caren Naomi Aguero Ito, Ediane Bortolotte Cornelius, Fernanda Brioli Lima, Andrea Marisa Sachilarid Rodrigues, Nathália Belmal Costa, Felipe Francisco Bittencourt, Fernando Freitas de Lima, Marina Meirelles Paes, Priscila Gubert, Silvia Aparecida Oesterreich

Publikováno v: PLoS ONE, Vol 15, Iss 1, p e0227105 (2020)

BACKGROUND:Diabetes mellitus is one of the most common todays public health problems. According to a survey by the World Health Organization, this metabolic disorder has reached global epidemic proportions, with a worldwide prevalence of 8.5% in the

Externí odkaz: https://doaj.org/article/5691f6a83a804052b6ba9f2a7a611156

Evaluation of the effect of alpha-tocopherol on anxiety and the neuroinflammatory process during alcohol withdrawal in a model of forced and chronic self-administration of liquid diet containing ethanol: Behavioral and neurochemical evidence

Autor: Gustavo Roberto, Villas Boas, Marina Meirelles, Paes, Mila Silva, Cunha, Luis Felipe, Ponsoni, Ana Paula, Stefanello da Silveira, Silvia Aparecida, Oesterreich

Publikováno v: Alcohol. 104:31-44

Alcoholism affects about 2 billion people worldwide. Withdrawal causes a neuroinflammatory response that increases anxiety. α-tocopherol is the most important antioxidant that has its in vivo action currently known. Therefore, this study aimed to ev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f7c089edc2329c08d3629f7a6d8aa40
https://doi.org/10.1016/j.alcohol.2022.08.002

The ethanolic extract obtained from Campomanesia pubescens (D.C.) O.BERG fruits exerts anxiolytic and antidepressant effects on chronic mild stress model and on anxiety models in Wistar rats: Behavioral evidences

Autor: Gustavo Roberto Villas Boas, Brunna Charlla Feitosa Farinelli, Ana Paula Stefanello da Silveira, Emely Arce, Silvia Aparecida Oesterreich, Claudia Andrea Lima Cardoso

Publikováno v: Nutritional Neuroscience. 23:16-26

Objectives: Campomanesia pubescens (DC) O.BERG (Myrtaceae) fruits contain high levels of flavonoids and are widely consumed by the South American population. In the central nervous system (CNS), so...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::636c8b91b299bf98e8b46600a458b886
https://doi.org/10.1080/1028415x.2018.1466513

PCR sensitivity of peripheral blood of dogs co-infected with Leishmania spp. and Ehrlichia spp. in endemic area of Brazil

Autor: Manoel Sebastião da Costa Lima Junior, Herintha Coeto Neitzke-Abreu, Leticia Surian Batalini, Silvia Barbosa do Carmo, Elisabete Friozi, Victor Bruno Duarte Vieira, Eduardo José de Arruda, Ana Paula Stefanello da Silveira

Publikováno v: Revista da Sociedade Brasileira de Medicina Tropical, Volume: 51, Issue: 6, Pages: 843-847, Published: DEC 2018
Revista da Sociedade Brasileira de Medicina Tropical, Vol 51, Iss 6, Pp 843-847

INTRODUCTION Peripheral blood of 400 dogs infected with Leishmania and Ehrlichia were analyzed using polymerase chain reaction (PCR), and clinical signs were characterized. METHODS PCR and parasitological tests were conducted. RESULTS PCR was positiv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c11da8ce9af0132940ee00fdc65cdd2
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822018000600843&lng=en&tlng=en

Preclinical safety evaluation of the aqueous extract from Mangifera indica Linn. (Anacardiaceae): genotoxic, clastogenic and cytotoxic assessment in experimental models of genotoxicity in rats to predict potential human risks

Autor: Marina Meirelles Paes, Priscila Gubert, Gustavo Roberto Villas Boas, Rafael Claudino dos Santos, Matheus William de Oliveira, Ediane Bortolotte Cornelius, Caren Naomi Aguero Ito, Silvia Aparecida Oesterreich, Andrea Marisa Sachilarid Rodrigues, Fernanda Brioli Lima, Nathália Belmal Costa, Ana Paula Stefanello da Silveira, Flávia Barbieri Bacha, Fernando Freitas de Lima, Felipe Francisco Bittencourt, João Marcos Rodrigues Lemos

Publikováno v: Journal of Ethnopharmacology. 243:112086

Ethnopharmacological relevance Medicinal plants widely used by the population contain significant concentrations of biologically active compounds and, although they have proven pharmacological properties, can cause DNA damage and develop fatal diseas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a95c7cb31c6dc875a6a675ad6fd7c477
https://doi.org/10.1016/j.jep.2019.112086