Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Ana Paula Rocha Gadelha"'
Publikováno v:
Histochemistry and Cell Biology. 157:251-265
The parasitic protozoan Giardia intestinalis, the causative agent of giardiasis, presents a stable and elaborated cytoskeleton, which shapes and supports several intracellular structures, including the ventral disc, the median body, the funis, and fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b78baf48f95136b1cc3c2e9484f1edb5
https://doi.org/10.1007/s00418-021-02060-2
https://doi.org/10.1007/s00418-021-02060-2
Publikováno v:
Lifecycles of Pathogenic Protists in Humans ISBN: 9783030806811
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b42fd34685cb5f4078d249a13dc6a0ca
https://doi.org/10.1007/978-3-030-80682-8_11
https://doi.org/10.1007/978-3-030-80682-8_11
Autor:
Ana Paula Rocha Gadelha, Franz Bracher, Lissa Catherine Reignault, Bruno Cosme, Bárbara Bravim, Kilian Huber, Juliana C. Vidal, Wanderley de Souza
Publikováno v:
International Journal of Medical Microbiology. 309:130-142
Giardia trophozoites have developed resistance mechanisms to currently available compounds, leading to treatment failures. In this context, the development of new additional agents is mandatory. Sirtuins, which are class III NAD+-dependent histone de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5e626ec09b131e8db25135c9c5ec714
https://doi.org/10.1016/j.ijmm.2019.01.002
https://doi.org/10.1016/j.ijmm.2019.01.002
Publikováno v:
Advances in parasitology. 107
Giardia intestinalis, the causative agent of giardiasis, has complex cytoskeleton organization with structures involved in motility, adhesion, cell division, and cell differentiation. Microtubules are key components of the cytoskeleton and are the ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::55378e1e3e2e5d41fbdea3792043f393
https://pubmed.ncbi.nlm.nih.gov/32122527
https://pubmed.ncbi.nlm.nih.gov/32122527
Giardia intestinalis, the causative agent of giardiasis, has complex cytoskeleton organization with structures involved in motility, adhesion, cell division, and cell differentiation. Microtubules are key components of the cytoskeleton and are the ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87f31f3e05e720a13b172c71c0be6497
https://doi.org/10.1016/bs.apar.2019.08.003
https://doi.org/10.1016/bs.apar.2019.08.003
Autor:
Rafael Castillo, Alicia Hernández-Campos, Benjamín Nogueda-Torres, Lilián Yépez-Mulia, Carlos A. Méndez-Cuesta, Jose M Hernandez, Félix Matadamas-Martínez, Ana Paula Rocha Gadelha, Wanderley de Souza
Publikováno v:
Research in Veterinary Science. 105:171-179
In an effort to develop alternative drugs for the treatment of giardiasis our research group has synthesized and evaluated a novel nitazoxanide and N-methyl-1H-benzimidazole hybrid molecule, named CMC-20. It showed an IC50 of 0.010 μM on Giardia int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be66d93866e632681908d0d796ea0465
https://doi.org/10.1016/j.rvsc.2016.02.006
https://doi.org/10.1016/j.rvsc.2016.02.006
Publikováno v:
Journal of Structural Biology. 184:280-292
The flagellar cytoskeleton of Leishmania promastigotes contains the canonical 9+2 microtubular axoneme and a filamentous structure, the paraflagellar rod (PFR), which is present alongside the axoneme. In contrast to promastigotes, which contain a lon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::238d9fcdd258158dbfa2b1fac86fcfd1
https://doi.org/10.1016/j.jsb.2013.09.006
https://doi.org/10.1016/j.jsb.2013.09.006
Publikováno v:
FEMS Microbiology Letters. 275:292-300
Tritrichomonas foetus is a venereal pathogen of cattle, which causes infertility, early embryonic death or abortion. In order to evaluate the potential trichomonicidal activity of benzimidazoles, the effects of thiabendazole, mebendazole and albendaz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba62f2cdbe751c945c6494d95460cef3
https://doi.org/10.1111/j.1574-6968.2007.00897.x
https://doi.org/10.1111/j.1574-6968.2007.00897.x
Publikováno v:
Parasitology Research. 101:1401-1406
In this work, we describe a semiautomated computer method to evaluate the activity of a common drug solvent, dimethyl sulfoxide (DMSO), on in vitro Giardia lamblia-host cell interaction. To compare the number of intestinal cells (IEC-6) and the adher
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32fb3d8e7f4b833ccf071768d46c7ed3
https://doi.org/10.1007/s00436-007-0661-1
https://doi.org/10.1007/s00436-007-0661-1