Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Ana P. Candiota"'
Autor:
Kai Zhao, Pilar Calero-Pérez, Miriam H. A. Bopp, Vincent Möschl, Axel Pagenstecher, Marta Mulero-Acevedo, Mario Vázquez, Carlos Barcia, Carles Arús, Christopher Nimsky, Tillmann Rusch, Jörg W. Bartsch, Ana Paula Candiota
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 24, p 17628 (2023)
The tumor microenvironment in glioblastoma (GB) is considered to be “cold”, i.e., the fraction of cytotoxic T cells, for instance, is low. Instead, macrophages are the major immune cell population in GB, which stem either from tissue response (re
Externí odkaz:
https://doaj.org/article/c45c798956f541c28aa98a2d1cd8b57e
Autor:
Paula Alfonso-Triguero, Julia Lorenzo, Ana Paula Candiota, Carles Arús, Daniel Ruiz-Molina, Fernando Novio
Publikováno v:
Nanomaterials, Vol 13, Iss 10, p 1619 (2023)
Current therapies for treating Glioblastoma (GB), and brain tumours in general, are inefficient and represent numerous challenges. In addition to surgical resection, chemotherapy and radiotherapy are presently used as standards of care. However, trea
Externí odkaz:
https://doaj.org/article/6fd0f54afbb346ba9deddff071f55a36
Autor:
Sergi Rodriguez-Calado, Petra Van Damme, Francesc Xavier Avilés, Ana Paula Candiota, Sebastian Tanco, Julia Lorenzo
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 2, p 1273 (2023)
The cytosolic carboxypeptidase 6 (CCP6) catalyzes the deglutamylation of polyglutamate side chains, a post-translational modification that affects proteins such as tubulins or nucleosome assembly proteins. CCP6 is involved in several cell processes,
Externí odkaz:
https://doaj.org/article/30c6e0dd83a8425d921cd480feaae21d
Autor:
Xiaoman Mao, Pilar Calero-Pérez, David Montpeyó, Jordi Bruna, Victor J. Yuste, Ana Paula Candiota, Julia Lorenzo, Fernando Novio, Daniel Ruiz-Molina
Publikováno v:
Nanomaterials, Vol 12, Iss 7, p 1221 (2022)
Cisplatin has been described as a potent anticancer agent for decades. However, in the case of glioblastomas, it is only considered a rescue treatment applied after the failure of second-line treatments. Herein, based on the versatility offered by co
Externí odkaz:
https://doaj.org/article/579be2546ab745b4ae742749793eac95
Autor:
Ana Paula Candiota, Carles Arús
Publikováno v:
Metabolites, Vol 12, Iss 3, p 243 (2022)
This hypothesis proposal addresses three major questions: (1) Why do we need imaging biomarkers for assessing the efficacy of immune system participation in glioblastoma therapy response? (2) Why are they not available yet? and (3) How can we produce
Externí odkaz:
https://doaj.org/article/52b9663795ca4699b4afc661164fdb6b
Autor:
Raúl Vicente Casaña-Eslava, Sandra Ortega-Martorell, Paulo J Lisboa, Ana Paula Candiota, Margarida Julià-Sapé, José David Martín-Guerrero, Ian H Jarman
Publikováno v:
PLoS ONE, Vol 15, Iss 7, p e0235057 (2020)
The aim of the paper is two-fold. First, we show that structure finding with the PC algorithm can be inherently unstable and requires further operational constraints in order to consistently obtain models that are faithful to the data. We propose a m
Externí odkaz:
https://doaj.org/article/8c6c2411cbf243ce9cacf2698ea40b47
Autor:
Sandra Ortega-Martorell, Ana Paula Candiota, Ryan Thomson, Patrick Riley, Margarida Julia-Sape, Ivan Olier
Publikováno v:
PLoS ONE, Vol 14, Iss 8, p e0220809 (2019)
Glioblastoma is the most frequent malignant intra-cranial tumour. Magnetic resonance imaging is the modality of choice in diagnosis, aggressiveness assessment, and follow-up. However, there are examples where it lacks diagnostic accuracy. Magnetic re
Externí odkaz:
https://doaj.org/article/c0b3d904d0fe4a3a92c132b16e42d52c
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 7, p 3453 (2021)
Background: The relevance of the cancer immune cycle in therapy response implies that successful treatment may trigger the exposure or the release of immunogenic signals. Previous results with the preclinical GL261 glioblastoma (GB) showed that combi
Externí odkaz:
https://doaj.org/article/bd41e216887b4ffcb15a89fa80319b03
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 22, p 8775 (2020)
Glioblastomas (GBs) are malignant brain tumours with poor prognosis even after aggressive therapy. Programmed cell death-1 (PD-1) immune checkpoint blockade is a promising strategy in many types of cancer, but its therapeutic effects in GB remain low
Externí odkaz:
https://doaj.org/article/9375624c71954b889f7aefbdd1e20841
Autor:
Xiaoman Mao, Shuang Wu, Pilar Calero-Pérez, Ana P. Candiota, Paula Alfonso, Jordi Bruna, Victor J. Yuste, Julia Lorenzo, Fernando Novio, Daniel Ruiz-Molina
Publikováno v:
Cancers
Cancers, Vol 14, Iss 410, p 410 (2022)
Dipòsit Digital de la UB
Universidad de Barcelona
Cancers; Volume 14; Issue 2; Pages: 410
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Cancers, Vol 14, Iss 410, p 410 (2022)
Dipòsit Digital de la UB
Universidad de Barcelona
Cancers; Volume 14; Issue 2; Pages: 410
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Glioblastoma is the most malignant and frequently occurring type of brain tumors in adults. Its treatment has been greatly hampered by the difficulty to achieve effective therapeutic concentration in the tumor sites due to its location and the blood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea58c599af59a49701951f26d45002f6
https://pubmed.ncbi.nlm.nih.gov/35053575
https://pubmed.ncbi.nlm.nih.gov/35053575