Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Ana Orive‐Ramos"'
Publikováno v:
Molecular Oncology, Vol 11, Iss 12, Pp 1788-1805 (2017)
Metastatic dissemination of tumor cells is responsible for the fatal outcome of breast cancer. Therefore, understanding the mechanisms involved in dissemination is essential for the development of new therapeutic strategies to prevent metastasis. One
Externí odkaz:
https://doaj.org/article/24a2768018694eb8985ee922cb493477
Autor:
Beau Baars, Christos Adamopoulos, Ana Orive-Ramos, Stuart A. Aaronson, Poulikos I. Poulikakos
Publikováno v:
Cancer Research. 83:3413-3413
Activating RAS mutations constitute the majority of recurrent mutations found in MAPK-driven human tumors. However, RAS mutants have long been considered undruggable, and therefore efforts have been predominantly focused on targeting downstream MAPK
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95108abe3d4626b99a092471e73d8495
https://doi.org/10.1158/1538-7445.am2023-3413
https://doi.org/10.1158/1538-7445.am2023-3413
Autor:
Ana Orive-Ramos, Christos Adamopoulos, Beau Baars, Jason Lam, Ankita Punetha, Jason Huang, Vasileios I. Petrou, Stuart A. Aaronson, Poulikos I. Poulikakos
Publikováno v:
Cancer Research. 83:5734-5734
Oncogenic alterations of the RAS/RAF/MEK/ERK signaling pathway drives growth of over 40% of human tumors, frequently due to activating mutations of components of the pathway, such as RAS or BRAF. Targeting the pathway using BRAF inhibitors (BRAFi) in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af501ff574c8dc99e6b5710211667b5e
https://doi.org/10.1158/1538-7445.am2023-5734
https://doi.org/10.1158/1538-7445.am2023-5734
Publikováno v:
Molecular Oncology
Digital.CSIC. Repositorio Institucional del CSIC
instname
Molecular Oncology, Vol 11, Iss 12, Pp 1788-1805 (2017)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Molecular Oncology, Vol 11, Iss 12, Pp 1788-1805 (2017)
Metastatic dissemination of tumor cells is responsible for the fatal outcome of breast cancer. Therefore, understanding the mechanisms involved in dissemination is essential for the development of new therapeutic strategies to prevent metastasis. One
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7a09c65f076fa961a634479e3abfb06
https://doi.org/10.1002/1878-0261.12145
https://doi.org/10.1002/1878-0261.12145