Výsledky vyhledávání - "Ana Muniz-Lozano"

Cigarette Smoking and Antiplatelet Effects of Aspirin Monotherapy Versus Clopidogrel Monotherapy in Patients with Atherosclerotic Disease: Results of a Prospective Pharmacodynamic Study

Autor: Jung Rae Cho, Francesco Franchi, Fabiana Rollini, Martin M. Zenni, Ronakkumar Patel, Antonio Tello-Montoliu, Dominick J. Angiolillo, Jose-Luis Ferreiro, Bhaloo Desai, Luis A. Guzman, Theodore A. Bass, Andrew Darlington, Ana Muniz-Lozano, Elisabetta Ferrante, Mona Bhatti, Christopher DeGroat

Publikováno v: Journal of Cardiovascular Translational Research. 7:53-63

Smokers have a greater relative benefit of clopidogrel therapy compared with nonsmokers, likely attributed to its enhanced pharmacodynamic (PD) effects. However, to date, all PD studies have been conducted in patients on dual antiplatelet therapy wit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fac7078e29a54b621712e414ad094c57
https://doi.org/10.1007/s12265-013-9535-3

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Cangrelor: a review on pharmacology and clinical trial development

Autor: Jung Rae Cho, Dominick J. Angiolillo, Ana Muniz-Lozano, Fabiana Rollini, Francesco Franchi

Publikováno v: Expert Review of Cardiovascular Therapy. 11:1279-1291

Dual antiplatelet therapy with aspirin and an oral ADP P2Y12 receptor antagonist is the standard-of-care for the prevention of ischemic events in patients with acute coronary syndrome or undergoing percutaneous coronary intervention (PCI). However, c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b2ca4905a11778f6a46b54f8b376e5c
https://doi.org/10.1586/14779072.2013.837701

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Pharmacodynamic effects of EV-077 in patients with diabetes mellitus and coronary artery disease on aspirin or clopidogrel monotherapy: results of an in vitro pilot investigation

Autor: Bhaloo Desai, Ana Muniz-Lozano, Andrew Darlington, Norbert Bender, Ryan E. Wilson, Kjell S. Sakariassen, Ronakkumar Patel, Fabiana Rollini, Francesco Franchi, Dominick J. Angiolillo, Antonio Tello-Montoliu

Publikováno v: Journal of Thrombosis and Thrombolysis. 37:131-138

Patients with diabetes mellitus (DM) have increased propensity to generate thromboxane A2 (TXA2) and other eicosanoids which can contribute to their heightened platelet reactivity. EV-077 is a potent thromboxane receptor antagonist and thromboxane sy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e069ce5e9c1d4a7df11e00c8fc483eff
https://doi.org/10.1007/s11239-013-0979-8

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Impact of aspirin dose on adenosine diphosphate-mediated platelet activities

Autor: Ana Muniz-Lozano, Francesco Franchi, Andrew Darlington, Luis A. Guzman, Fabiana Rollini, Bhaloo Desai, Dominick J. Angiolillo, Estela Thano, Ryan E. Wilson, Theodore A. Bass, Ronakkumar Patel, Antonio Tello-Montoliu

Publikováno v: Thrombosis and Haemostasis. 110:777-784

SummaryDifferent aspirin dosing regimens have been suggested to impact outcomes when used in combination with adenosine diphosphate (ADP) P2Y12 receptor antagonists. Prior investigations have shown that not only aspirin, but also potent ADP P2Y12 rec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fac04ff4ae0ac826dd82aaf8fc638673
https://doi.org/10.1160/th13-05-0400

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A head-to-head pharmacodynamic comparison of prasugrel vs. ticagrelor after switching from clopidogrel in patients with coronary artery disease: results of a prospective randomized study

Autor: Kamaldeep Singh, Elizabeth C Dunn, Jung Rae Cho, Mona Bhatti, Theodore A. Bass, Martin M. Zenni, Elisabetta Ferrante, Luis A. Guzman, Ana Muniz-Lozano, Christopher DeGroat, Francesco Franchi, Ryan E. Wilson, Dominick J. Angiolillo, Fabiana Rollini

Publikováno v: European heart journal. 37(35)

Pharmacodynamic (PD) studies comparing prasugrel and ticagrelor have reached inconsistent findings. Therefore, a comprehensive investigation comparing the PD effects of prasugrel vs. ticagrelor after switching from clopidogrel therapy, exploring both

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85c57c97a98957d67111d6b74f5572ce
https://pubmed.ncbi.nlm.nih.gov/27190104

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Pharmacodynamic Effects of Ticagrelor Dosing Regimens in Patients on Maintenance Ticagrelor Therapy: Results From a Prospective, Randomized, Double-Blind Investigation

Autor: Jung Rae, Cho, Fabiana, Rollini, Francesco, Franchi, Christopher, DeGroat, Mona, Bhatti, Elizabeth C, Dunn, Elisabetta, Ferrante, Ana, Muniz-Lozano, Siva, Suryadevara, Martin M, Zenni, Luis A, Guzman, Theodore A, Bass, Dominick J, Angiolillo

Publikováno v: JACC. Cardiovascular interventions. 8(8)

The aim of this study was to assess the impact of ticagrelor dosing regimens on pharmacodynamic (PD) profiles in patients on maintenance ticagrelor therapy.Many patients on maintenance P2Y12-inhibiting therapies may require coronary revascularization

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9b929d5642b61c045965213b042a7fca
https://pubmed.ncbi.nlm.nih.gov/26117466

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Abstract 16419: A Comparative Analysis of Prasugrel versus Ticagrelor on Rates of High On-Treatment Platelet Reactivity Following Switch From Clopidogrel Therapy

Autor: Fabiana Rollini, Jung Rae Cho, Francesco Franchi, Mona Bhatti, Christopher DeGroat, Mohamad Taha, Ana Muniz-Lozano, Kamaldeep Singh, Elisabetta Ferrante, Elizabeth C Dunn, Martin M Zenni, Luis A Guzman, Theodore A Bass, Dominick J Angiolillo

Publikováno v: Circulation. 130

Background: Clopidogrel is characterized by non-uniform pharmacodynamic (PD) effects leading to considerable rates of high on-treatment platelet reactivity (HPR), a marker of increased atherothrombotic risk. Prasugrel and ticagrelor have greater pote

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a74dff6941bab4179ab76295650ef9db
https://doi.org/10.1161/circ.130.suppl_2.16419

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Antithrombotic Issues in Women

Autor: Ana Muniz-Lozano, Francesco Franchi, Jung Rae Cho, Fabiana Rollini, Dominick J. Angiolillo

Publikováno v: Management of Cardiovascular Disease in Women ISBN: 9781447155164

Despite the numerous randomized trials that have evaluated the use of antithrombotic therapy in the setting of acute coronary syndromes (ACS) and atrial fibrillation (AF), the heterogeneity of the population enrolled in the majority of these studies

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bb41dfdeb4a17572820425958fc4444e
https://doi.org/10.1007/978-1-4471-5517-1_15

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Impact of cigarette smoking on P2Y12 receptor binding activity before and after clopidogrel therapy in patients with coronary artery disease

Autor: Jung Rae Cho, Antonio Tello-Montoliu, Bhaloo Desai, Francesco Franchi, Elisabetta Ferrante, Dominick J. Angiolillo, Fabiana Rollini, Theodore A. Bass, Luis A. Guzman, Ana Muniz-Lozano, Michael J. Haas

Publikováno v: Journal of cardiovascular translational research. 7(1)

Smoking enhances the P2Y12 receptor inhibitory effects of clopidogrel. Nicotine increases P2Y12 receptor expression in platelet lysates from healthy volunteers. However, the impact of cigarette smoking on platelet P2Y12 receptor binding in clopidogre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64c17fe5e67ea1aa51e524cedd189f2f
https://pubmed.ncbi.nlm.nih.gov/24357254

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