Polymorphisms within the TNFSF4 and MAPKAPK2 Loci Influence the Risk of Developing Invasive Aspergillosis: A Two-Stage Case Control Study in the Context of the aspBIOmics Consortium

Autor: Jose Manuel Sánchez-Maldonado, Ana Moñiz-Díez, Rob ter Horst, Daniele Campa, Antonio José Cabrera-Serrano, Manuel Martínez-Bueno, María del Pilar Garrido-Collado, Francisca Hernández-Mohedo, Laura Fernández-Puerta, Miguel Ángel López-Nevot, Cristina Cunha, Pedro Antonio González-Sierra, Jan Springer, Michaela Lackner, Laura Alcazar-Fuoli, Luana Fianchi, José María Aguado, Livio Pagano, Elisa López-Fernández, Esther Clavero, Leonardo Potenza, Mario Luppi, Lucia Moratalla, Carlos Solano, Antonio Sampedro, Manuel Cuenca-Estrella, Cornelia Lass-Flörl, PCRAGA Study Group, Federico Canzian, Juergen Loeffler, Yang Li, Hermann Einsele, Mihai G. Netea, Lourdes Vázquez, Agostinho Carvalho, Manuel Jurado, Juan Sainz

Publikováno v: Journal of Fungi, Vol 7, Iss 1, p 4 (2020)

Here, we assessed whether 36 single nucleotide polymorphisms (SNPs) within the TNFSF4 and MAPKAPK2 loci influence the risk of developing invasive aspergillosis (IA). We conducted a two-stage case control study including 911 high-risk patients diagnos

Externí odkaz: https://doaj.org/article/7ffd7f2e74154c68aeb332e792fad767

Polymorphisms within the TNFSF4 and mapkapk2 loci influence the risk of developing invasive aspergillosis: A two-stage case control study in the context of the aspbiomics consortium

Autor: Juan Sainz, Pedro Antonio González-Sierra, Laura Fernández-Puerta, Francisca Hernández-Mohedo, Antonio José Cabrera-Serrano, Livio Pagano, Manuel Martínez-Bueno, Esther Clavero, Carlos Solano, Hermann Einsele, Luana Fianchi, Manuel Cuenca-Estrella, Yang Li, Antonio Sampedro, María Del Pilar Garrido-Collado, Rob ter Horst, Elisa López-Fernández, Lourdes Vázquez, Agostinho Carvalho, Leonardo Potenza, Mario Luppi, Juergen Loeffler, Manuel Jurado, Lucía Moratalla, Laura Alcazar-Fuoli, José María Aguado, Federico Canzian, Miguel A. López-Nevot, Michaela Lackner, Daniele Campa, Jose Manuel Sánchez-Maldonado, Jan Springer, Cornelia Lass-Flörl, Ana Moñiz-Díez, Cristina Cunha, Mihai G. Netea

Publikováno v: Digibug. Repositorio Institucional de la Universidad de Granada
instname
Journal of Fungi
Volume 7
Issue 1
Digibug: Repositorio Institucional de la Universidad de Granada
Universidad de Granada (UGR)
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Journal of Fungi, 7, 1
Journal of Fungi, 7
Repisalud
Instituto de Salud Carlos III (ISCIII)
Journal of Fungi, Vol 7, Iss 4, p 4 (2021)

Here, we assessed whether 36 single nucleotide polymorphisms (SNPs) within the TNFSF4 and MAPKAPK2 loci influence the risk of developing invasive aspergillosis (IA). We conducted a twostage case control study including 911 high-risk patients diagnose

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3c0873e2d47c647a86557fcdf82a60f
http://hdl.handle.net/10807/176223

NFKB2 polymorphisms associate with the risk of developing rheumatoid arthritis and response to TNF inhibitors: Results from the REPAIR consortium

Autor: Helena Canhão, Pablo Conesa-Zamora, Salvatore De Vita, Alfons A den Broeder, Sonia Muñoz-Peña, Antonio García, Luca Quartuccio, Rafael Cáliz, Yang Li, Alejandro Escudero, Mihai G. Netea, Svend Erik Hove Jacobsen, Eduardo Collantes, Ana Rodríguez-Ramos, Manuel Jurado, Merete Lund Hetland, Miguel Ferrer, Manuel Martínez-Bueno, João Eurico Fonseca, Jose Manuel Sánchez-Maldonado, Rob ter Horst, Miguel A. López-Nevot, Signe Bek Sørensen, Marieke J H Coenen, Juan Sainz, I. Filipescu, Eva Perez-Pampin, Vibeke Andersen, Ana Moñiz-Díez, Bente Glintborg

Publikováno v: Scientific Reports, 10
Digibug. Repositorio Institucional de la Universidad de Granada
Consejo Superior de Investigaciones Científicas (CSIC)
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Manuel Sánchez-Maldonado, J, Martínez-Bueno, M, Canhão, H, ter Horst, R, Muñoz-Peña, S, Moñiz-Díez, A, Rodríguez-Ramos, A, Escudero, A, Sorensen, S B, Hetland, M L, Ferrer, M A, Glintborg, B, Filipescu, I, Pérez-Pampin, E, Conesa-Zamora, P, García, A, den Broeder, A, De Vita, S, Hove Jacobsen, S E, Collantes, E, Quartuccio, L, Netea, M G, Li, Y, Fonseca, J E, Jurado, M, López-Nevot, M Á, Coenen, M J H, Andersen, V, Cáliz, R & Sainz, J 2020, ' NFKB2 polymorphisms associate with the risk of developing rheumatoid arthritis and response to TNF inhibitors : Results from the REPAIR consortium ', Scientific Reports, vol. 10, 4316 . https://doi.org/10.1038/s41598-020-61331-5
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Digibug: Repositorio Institucional de la Universidad de Granada
Universidad de Granada (UGR)
Scientific Reports
Scientific Reports, 10(1):4316. Nature Publishing Group
Manuel Sánchez-Maldonado, J, Martínez-Bueno, M, Canhão, H, ter Horst, R, Muñoz-Peña, S, Moñiz-Díez, A, Rodríguez-Ramos, A, Escudero, A, Sorensen, S B, Hetland, M L, Ferrer, M A, Glintborg, B, Filipescu, I, Pérez-Pampin, E, Conesa-Zamora, P, García, A, den Broeder, A, De Vita, S, Hove Jacobsen, S E, Collantes, E, Quartuccio, L, Netea, M G, Li, Y, Fonseca, J E, Jurado, M, López-Nevot, M Á, Coenen, M J H, Andersen, V, Cáliz, R & Sainz, J 2020, ' NFKB2 polymorphisms associate with the risk of developing rheumatoid arthritis and response to TNF inhibitors : Results from the REPAIR consortium ', Scientific Reports, vol. 10, no. 1, 4316 . https://doi.org/10.1038/s41598-020-61331-5

We thank all participants who have agreed to participate in this study. Authors also thank Maria Dolores Casares, Angeles Molina, Carmen Oloriz for the collection of Spanish samples and Hans Jurgen Hoffmann, Marianne Thomsen, Vibeke Ostergaard Thomse

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f17f95bce91f62736192280b55f57ac
http://hdl.handle.net/2066/218299

OP0017 VALIDATION OF GWAS-IDENTIFIED VARIANTS FOR ANTI-TNF DRUG RESPONSE IN RHEUMATOID ARTHRITIS: A META-ANALYSIS OF THREE LARGE COHORTS

Autor: João Eurico Fonseca, E. Collantes Estevez, Marieke J H Coenen, Jerzy Swierkot, Miguel A. López-Nevot, Juan Sainz, Signe Bek Sørensen, R. Ter Horst, Katarzyna Bogunia-Kubik, Jose Manuel Sánchez-Maldonado, Antonio José Cabrera-Serrano, Vibeke Andersen, R. Cáliz Cáliz, I. Filipescu, Ana Moñiz-Díez, S. De Vita, Helena Canhão, Pablo Conesa-Zamora, Yi Li, A.A. den Broeder, Luca Quartuccio, M. Á. Ferrer González, S. E. Hove Jaconsen, Eva Perez-Pampin, B. Glintborg, A. Escudero Contreras, Merete Lund Hetland, Mihai G. Netea

Publikováno v: Annals of the Rheumatic Diseases. 80:9.2-10

Background:The interplay between genetics and drug response in rheumatoid arthritis (RA) has shown that response to biologics varies between individuals and that a large proportion of patients show no clinical improvement (Plenge and Bridges, 2011).

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::38af81e136e10465f19ff7b9cb4bad5d
https://doi.org/10.1136/annrheumdis-2021-eular.2248