Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Ana Marote"'
Autor:
Bárbara Mendes-Pinheiro, Jonas Campos, Ana Marote, Carina Soares-Cunha, Sarah L. Nickels, Anna S. Monzel, Jorge R. Cibrão, Eduardo Loureiro-Campos, Sofia C. Serra, Sandra Barata-Antunes, Sara Duarte-Silva, Luísa Pinto, Jens C. Schwamborn, António J. Salgado
Publikováno v:
Cells, Vol 12, Iss 21, p 2565 (2023)
Parkinson’s disease (PD) is the most common movement disorder, characterized by the progressive loss of dopaminergic neurons from the nigrostriatal system. Currently, there is no treatment that retards disease progression or reverses damage prior t
Externí odkaz:
https://doaj.org/article/d9ee2e845ba143418fd7dbee34549f1f
Autor:
Rita Silva-Pedrosa, Jonas Campos, Aline Marie Fernandes, Miguel Silva, Carla Calçada, Ana Marote, Olga Martinho, Maria Isabel Veiga, Ligia R. Rodrigues, António José Salgado, Pedro Eduardo Ferreira
Publikováno v:
Cells, Vol 12, Iss 7, p 984 (2023)
Neural injuries in cerebral malaria patients are a significant cause of morbidity and mortality. Nevertheless, a comprehensive research approach to study this issue is lacking, so herein we propose an in vitro system to study human cerebral malaria u
Externí odkaz:
https://doaj.org/article/cd08232ab7c947eb982dcc92cad2afb1
Autor:
Ana Marote, Yuriy Pomeshchik, Anna Collin, Stefano Goldwurm, Nuno J. Lamas, Luísa Pinto, António J. Salgado, Laurent Roybon
Publikováno v:
Stem Cell Research, Vol 28, Iss , Pp 44-47 (2018)
The leucine-rich repeat kinase 2 (LRRK2) p.G2019S mutation is the most common genetic cause of Parkinson's disease (PD). An induced pluripotent stem cell (iPSC) line CSC-41 was generated from a 75-year old patient diagnosed with PD caused by a p.G201
Externí odkaz:
https://doaj.org/article/3c1307d922004b9b8af5ea83b6878ec0
Autor:
Ana Marote, Yuriy Pomeshchik, Stefano Goldwurm, Anna Collin, Nuno J. Lamas, Luísa Pinto, António J. Salgado, Laurent Roybon
Publikováno v:
Stem Cell Research, Vol 27, Iss , Pp 82-85 (2018)
An induced pluripotent stem cell (iPSC) line was generated from a 36-year-old patient with sporadic Parkinson's disease (PD). Skin fibroblasts were reprogrammed using the non-integrating Sendai virus technology to deliver OCT3/4, SOX2, c-MYC and KLF4
Externí odkaz:
https://doaj.org/article/5144805d344f4ce49d2893555df895a8
Autor:
Ekaterina Savchenko, Ana Marote, Kaspar Russ, Anna Collin, Stefano Goldwurm, Laurent Roybon, Yuriy Pomeshchik
Publikováno v:
Stem Cell Research, Vol 27, Iss , Pp 78-81 (2018)
Skin fibroblasts were collected from a 44-year-old patient with sporadic case of Parkinson's disease (PD). The non-integrating Sendai virus vector encoding OCT3/4, SOX2, c-MYC and KLF4 was used to reprogram fibroblasts into induced pluripotent stem c
Externí odkaz:
https://doaj.org/article/4221f0ddd07a41e883ade90cf7152eb0
Autor:
Kaspar Russ, Ana Marote, Ekaterina Savchenko, Anna Collin, Stefano Goldwurm, Yuriy Pomeshchik, Laurent Roybon
Publikováno v:
Stem Cell Research, Vol 27, Iss , Pp 61-64 (2018)
Parkinson's disease (PD) is a neurodegenerative disease with unknown etiology. Here we show the generation of an induced pluripotent stem cell (iPSC) line, named CSC-40, from dermal fibroblasts obtained from a 59-year-old male patient with a homozygo
Externí odkaz:
https://doaj.org/article/8252c797347843ccafa3c9b14abca2e1
Autor:
Ana Marote, Yuriy Pomeshchik, Stefano Goldwurm, Anna Collin, Nuno J. Lamas, Luísa Pinto, António J. Salgado, Laurent Roybon
Publikováno v:
Stem Cell Research, Vol 27, Iss , Pp 90-94 (2018)
Mutations in the PARK2 gene, which encodes PARKIN, are the most frequent cause of autosomal recessive Parkinson's disease (PD). We report the generation of an induced pluripotent stem cell (iPSC) line from a 78-year-old patient carrying a compound he
Externí odkaz:
https://doaj.org/article/9153e7a5f2264db496d106fe0fcdbb53
Autor:
Bárbara Mendes-Pinheiro, Sandra I. Anjo, Bruno Manadas, Jorge D. Da Silva, Ana Marote, Leo A. Behie, Fábio G. Teixeira, António J. Salgado
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 7 (2019)
Parkinson's disease (PD) is characterized by a selective loss of dopamine (DA) neurons in the human midbrain causing motor dysfunctions. The exact mechanism behind dopaminergic cell death is still not completely understood and, so far, no cure or neu
Externí odkaz:
https://doaj.org/article/3db3ab5c908a46508b91dfacb1636c67
Autor:
Nadja Gustavsson, Ana Marote, Yuriy Pomeshchik, Kaspar Russ, Carla Azevedo, Margarita Chumarina, Stefano Goldwurm, Anna Collin, Luisa Pinto, António J. Salgado, Oxana Klementieva, Laurent Roybon, Ekaterina Savchenko
Publikováno v:
Stem Cell Research, Vol 34, Iss , Pp - (2019)
Mutations in the glucocerebrosidase (GBA) gene have been associated with the development of Parkinson's disease (PD). An induced pluripotent stem cell (iPSC) line was generated from a 60-year old patient diagnosed with PD and carrying a new mutation
Externí odkaz:
https://doaj.org/article/ca7e3c96796647ecb91685b9845b1e55
Autor:
Ana Marote, Nathalie Barroca, Rui Vitorino, Raquel M. Silva, Maria H.V. Fernandes, Paula M. Vilarinho, Odete A.B. da Cruz e Silva, Sandra I. Vieira
Publikováno v:
AIMS Molecular Science, Vol 3, Iss 4, Pp 661-682 (2016)
Poly (L-lactic acid) (PLLA) is a biodegradable and biocompatible polymer that has been put forward as a promising material for therapeutic approaches aiming to restore neuronal function. The topographic cues present in PLLA-based scaffolds, defined b
Externí odkaz:
https://doaj.org/article/28deb0fdb29140b393bbe2bc21c105a8