Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Ana Maria Storniolo"'
Autor:
Julie A. Douglas, Daniel L. Hertz, N. Lynn Henry, Zeruesenay Desta, Daniel F. Hayes, Todd C. Skaar, James M. Rae, Christina L. Gersch, Vered Stearns, Ana Maria Storniolo, Kelley M. Kidwell
Publikováno v:
Pharmacogenet Genomics
OBJECTIVE: Letrozole is a non-steroidal aromatase inhibitor (AI) used to treat hormone receptor positive (HR+) breast cancer. Variability in letrozole efficacy and toxicity may be partially attributable to variable systemic drug exposure, which may b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55c81e74856e2751dcbc047f621021d3
https://doi.org/10.1097/fpc.0000000000000429
https://doi.org/10.1097/fpc.0000000000000429
Autor:
Bryana J. Gregory, Jingyue Xi, Kelley M. Kidwell, Daniel F. Hayes, Ana Maria Storniolo, Daniel L. Hertz, Landry K. Kamdem, Vered Stearns, James M. Rae, Brandi L. Clark, N. Lynn Henry, Christina L. Gersch
Publikováno v:
Breast Cancer Res Treat
PURPOSE: UGT2B17 gene deletion (UGT2B17*2) has been reported to affect bone health as well as the pharmacokinetics of aromatase inhibitor (AI) drugs such as exemestane. The goal of this study was to assess associations between UGT2B17 gene deletion a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce572fbf0a014f87d9a08aad2c10b621
https://doi.org/10.1007/s10549-019-05158-3
https://doi.org/10.1007/s10549-019-05158-3
Autor:
Siri H Strand, Daisy Yi Ding, Gaorav P. Gupta, Belén Rivero-Gutiérrez, Bryan Harmon, Allison Hall, Kristalyn K. Gallagher, Kornelia Polyak, Lauren Anderson, Gabrielle B. Rocque, Robyn Burns, Jose A. Seoane, Lunden A Simpson, Katherine DeSchryver, Luis Cisneros, Tari King, Shu Jiang, Deborah J. Veis, Julie R. Nangia, Robert Tibshirani, Jeffrey R. Marks, Alastair M. Thompson, Robert B. West, Chunfang Zhu, Jason K. Wang, Ana Maria Storniolo, Priscilla F. McAuliffe, Jingqin Luo, Jennifer F. Tseng, Graham A. Colditz, E. Shelley Hwang, Cody Straub, Joanna Lee, Sujay Vennam, Dadong Zhang, Shirley Zhu, Lorraine M. King, Sushama Varma, Mark R. Kilgore, Timothy Hardman, Jen Tappenden, Angela DeMichele, Christina Curtis, Kouros Owzar, Robert M. Angelo, Magdalena Matusiak, Carlo C. Maley, Sucheta Srivastava, Kathleen E. Houlahan, Fergus J. Couch, Tyler Risom, Aziz Kahn
Publikováno v:
SSRN Electronic Journal.
Ductal carcinoma in situ (DCIS) is the most commonly diagnosed precursor of invasive breast cancer (IBC), with variable propensity for progression. We have performed the first multiscale, integrated profiling of DCIS with clinical outcomes to identif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf1a5d92c31e4996210d19fb6ee4d424
https://doi.org/10.2139/ssrn.3874170
https://doi.org/10.2139/ssrn.3874170
Autor:
Norah Lynn Henry, Faouzi Azzouz, Jason D. Robarge, Donghua Cao, Santosh Philips, Todd C. Skaar, Vered Stearns, James M. Rae, Ana Maria Storniolo, Daniel F. Hayes, David A. Flockhart, Anne T. Nguyen, Lang Li
Publikováno v:
British Journal of Cancer
Background: Tamoxifen, a selective oestrogen receptor (ER) modulator, increases bone mineral density (BMD) in postmenopausal women and decreases BMD in premenopausal women. We hypothesised that inherited variants in candidate genes involved in oestro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6402f24a332100bf44ea8351f1f332dc
https://doi.org/10.1038/sj.bjc.6605460
https://doi.org/10.1038/sj.bjc.6605460
Cytochrome P450 2D6 activity predicts discontinuation of tamoxifen therapy in breast cancer patients
Autor:
Matthew J. Sikora, David A. Flockhart, Todd C. Skaar, Norah Lynn Henry, Seongho Kim, Vered Stearns, Ana Maria Storniolo, Daniel F. Hayes, Steffi Oesterreich, Z. Desta, Anne T. Nguyen, James M. Rae, Lang Li
Publikováno v:
The pharmacogenomics journal. 9(4)
The selective estrogen receptor modulator tamoxifen is routinely used for treatment and prevention of estrogen receptor positive breast cancer. Studies of tamoxifen adherence suggest that over half of patients discontinue treatment before the recomme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4c61654b1f6f415b897934c9cfddda2
https://pubmed.ncbi.nlm.nih.gov/19421167
https://pubmed.ncbi.nlm.nih.gov/19421167