Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Ana Maria Quintela Pousa"'
Autor:
Federica Maria Conedera, Ana Maria Quintela Pousa, Nadia Mercader, Markus Tschopp, Volker Enzmann
Publikováno v:
Molecular Neurodegeneration, Vol 16, Iss 1, Pp 1-21 (2021)
Abstract Background Contrasting with zebrafish, retinal regeneration from Müller cells (MCs) is largely limited in mammals, where they undergo reactive gliosis that consist of a hypertrophic response and ultimately results in vision loss. Transformi
Externí odkaz:
https://doaj.org/article/43ff539d4e9d4da8a930484e568856aa
Autor:
Federica Maria Conedera, Ana Maria Quintela Pousa, Nadia Mercader, Markus Tschopp, Volker Enzmann
Publikováno v:
Molecular Neurodegeneration
Conedera, Federica Maria; Quintela Pousa, Ana Maria; Mercader Huber, Nadia Isabel; Tschopp, Markus; Enzmann, Volker (2021). The TGFβ/Notch axis facilitates Müller cell-to-epithelial transition to ultimately form a chronic glial scar. Molecular neurodegeneration, 16(1), p. 69. BioMed Central 10.1186/s13024-021-00482-z
Molecular Neurodegeneration, Vol 16, Iss 1, Pp 1-21 (2021)
Conedera, Federica Maria; Quintela Pousa, Ana Maria; Mercader Huber, Nadia Isabel; Tschopp, Markus; Enzmann, Volker (2021). The TGFβ/Notch axis facilitates Müller cell-to-epithelial transition to ultimately form a chronic glial scar. Molecular neurodegeneration, 16(1), p. 69. BioMed Central 10.1186/s13024-021-00482-z
Molecular Neurodegeneration, Vol 16, Iss 1, Pp 1-21 (2021)
Background Contrasting with zebrafish, retinal regeneration from Müller cells (MCs) is largely limited in mammals, where they undergo reactive gliosis that consist of a hypertrophic response and ultimately results in vision loss. Transforming growth
Autor:
David M. Presby, Ana Maria Quintela Pousa, Nadia Mercader, Federica Maria Conedera, Markus Tschopp, Volker Enzmann
Publikováno v:
Conedera, Federica Maria; Quintela Pousa, Ana Maria; Presby, David Mikal; Mercader, Nadia; Enzmann, Volker; Tschopp, Markus (2021). Diverse Signaling by TGFβ Isoforms in Response to Focal Injury is Associated with Either Retinal Regeneration or Reactive Gliosis. Cellular and molecular neurobiology, 41(1), pp. 43-62. Springer 10.1007/s10571-020-00830-5
Cellular and Molecular Neurobiology
Cellular and Molecular Neurobiology
Müller cells may have stem cell-like capability as they regenerate photoreceptor loss upon injury in some vertebrates, but not in mammals. Indeed, mammalian Müller cells undergo major cellular and molecular changes summarized as reactive gliosis. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3735c5d078eb139bde30287bd232e784
Publikováno v:
International Journal of Molecular Sciences
Volume 20
Issue 14
Trepp, Carolyn; Quintela Pousa, Ana Maria; Enzmann, Volker (2019). Transcriptome Analysis Did Not Show Endogenous Stem Cell Characteristics in Murine Lgr5+ Retinal Cells. International journal of molecular sciences, 20(14) Molecular Diversity Preservation International MDPI 10.3390/ijms20143547
International Journal of Molecular Sciences, Vol 20, Iss 14, p 3547 (2019)
Volume 20
Issue 14
Trepp, Carolyn; Quintela Pousa, Ana Maria; Enzmann, Volker (2019). Transcriptome Analysis Did Not Show Endogenous Stem Cell Characteristics in Murine Lgr5+ Retinal Cells. International journal of molecular sciences, 20(14) Molecular Diversity Preservation International MDPI 10.3390/ijms20143547
International Journal of Molecular Sciences, Vol 20, Iss 14, p 3547 (2019)
Lgr5, an intestinal adult stem cell marker, was recently also found in neuronal tissues. We investigated whether retinal Lgr5+ cells express properties of neural stem cells (NSC) and/or of differentiated interneurons during retinal development. RNA w
Autor:
Federica Maria Conedera, Markus Tschopp, Nadia Mercader, Ana Maria Quintela Pousa, Volker Enzmann
Publikováno v:
Glia. 67(6)
Microglia are the resident tissue macrophages of the central nervous system including the retina. Under pathophysiological conditions, microglia can signal to Muller cells, the major glial component of the retina, affecting their morphological, molec