Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Ana Maria Manso"'
Autor:
Yasuhiro Ichikawa, Alice E Zemljic-Harpf, Zheng Zhang, M Dan McKirnan, Ana Maria Manso, Robert S Ross, H Kirk Hammond, Hemal H Patel, David M Roth
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0177660 (2017)
Anthracyclines are chemotherapeutic drugs known to induce heart failure in a dose-dependent manner. Mechanisms involved in anthracycline cardiotoxicity are an area of relevant investigation. Caveolins bind, organize and regulate receptors and signali
Externí odkaz:
https://doaj.org/article/785157a1d7cc406e9698745e0dd63ed3
Publikováno v:
Integrins in Health and Disease ISBN: 9783031237805
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::120e6dd33adb3d1dfdc00e8579b466bc
https://doi.org/10.1007/978-3-031-23781-2_4
https://doi.org/10.1007/978-3-031-23781-2_4
Autor:
Chao Chen, Sherin I. Hashem, Jay Sharma, Ana Maria Manso, Paul Bushway, Jason M. Duran, Emily C. Gault, Yusu Gu, Jose Roberto Cano Nigenda, Angel Soto-Hermida, Kirk L. Peterson, Paul Saftig, Sylvia M. Evans, Stephanie Cherqui, Eric D. Adler
Danon disease is a fatal X-linked recessive disease caused by a lack of expression of the lysosomal associated membrane protein type 2 (LAMP2), leading to severe vacuolar cardiomyopathy. Most patients with Danon progress to end-stage heart failure or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5146d0625e544550f5f858ce26616d1f
https://doi.org/10.21203/rs.3.rs-1921280/v1
https://doi.org/10.21203/rs.3.rs-1921280/v1
Autor:
Kevin Tenerelli, Robert S. Ross, Chao Chen, Kirk L. Peterson, Nicholas J. Schork, Elie Farah, Ana Maria Manso, Ju Chen, Adam J. Engler, Qian Peng, Nancy D. Dalton, Dekker C. Deacon, Yusu Gu, Neil Tedeschi, Eric Adler, Ting Li, Vivien D. Tran, Neil C. Chi, Cassandra L. Happe
Publikováno v:
Nature Biomedical Engineering. 3:147-157
Dilated cardiomyopathy (DCM) is a leading cause of morbidity and mortality worldwide; yet how genetic variation and environmental factors impact DCM heritability remains unclear. Here, we report that compound genetic interactions between DNA sequence
Publikováno v:
Circulation Research. 127
Talin (Tln) is a component of muscle costameres that links integrins to other components of the cellular cytoskeleton and plays an important role in maintaining the cellular integrity of cardiac myocytes (CM). There are two talin genes, Tln1 and Tln2
Autor:
Dekker C, Deacon, Cassandra L, Happe, Chao, Chen, Neil, Tedeschi, Ana Maria, Manso, Ting, Li, Nancy D, Dalton, Qian, Peng, Elie N, Farah, Yusu, Gu, Kevin P, Tenerelli, Vivien D, Tran, Ju, Chen, Kirk L, Peterson, Nicholas J, Schork, Eric D, Adler, Adam J, Engler, Robert S, Ross, Neil C, Chi
Publikováno v:
Nature biomedical engineering. 3(2)
Dilated cardiomyopathy (DCM) is a leading cause of morbidity and mortality worldwide; yet how genetic variation and environmental factors impact DCM heritability remains unclear. Here, we report that compound genetic interactions between DNA sequence
Autor:
Paola Cattaneo, Jennifer Veevers, Yangzhao Zhou, Zhiyuan Zhang, Yongxin Mu, Angela K. Peter, Robert S. Ross, Ana Maria Manso, Jianlin Zhang, Xinmin Zhou, Kirk U. Knowlton, Sylvia M. Evans, Ju Chen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6560245c408f53f0e5b90e82428f42c
https://europepmc.org/articles/PMC6424132/
https://europepmc.org/articles/PMC6424132/
Autor:
Anne N. Murphy, Aleksander Andreyev, Yoshitake Cho, Oliver R. Zhang, Ana Maria Manso, Jianlin Zhang, Cameron Hill, Ruixia Li, Robert S. Ross, Sarah V. Schurr, Chao Chen, Shizuko Tachibana
Publikováno v:
J Vis Exp
Mitochondria and oxidative metabolism are critical for maintaining cardiac muscle function. Research has shown that mitochondrial dysfunction is an important contributing factor to impaired cardiac function found in heart failure. By contrast, restor
Autor:
Sherin Hashem, Kirk H. Hammond, Emily Gault, Kirk L. Peterson, Angel Soto-Hermida, Annahita Keravala, Nancy D. Dalton, Ana Maria Manso, Julius Bogomolovas, Paul Saftig, Yusu Gu, Elizza Villarruel, Gaurav D. Shah, Bradley C. Nelson, Pavan K. Battiprolu, Eric Adler, Jonathan D. Schwartz, Chao Chen, Paul J. Bushway, Michela Brambatti
Publikováno v:
Science translational medicine. 12(535)
Danon disease (DD) is a rare X-linked autophagic vacuolar myopathy associated with multiorgan dysfunction, including the heart, skeletal muscle, and liver. There are no specific treatments, and most male patients die from advanced heart failure durin
Publikováno v:
Pediatr Cardiol
Integrin receptors enable cells to sense and respond to their chemical and physical environment. As a class of membrane receptors, they provide a dynamic, tightly regulated link between the extracellular matrix or cellular counter-receptors and intra