Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Ana Maria Fernandez-Pujals"'
Autor:
Andrew M McIntosh, Lynsey S Hall, Yanni Zeng, Mark J Adams, Jude Gibson, Eleanor Wigmore, Saskia P Hagenaars, Gail Davies, Ana Maria Fernandez-Pujals, Archie I Campbell, Toni-Kim Clarke, Caroline Hayward, Chris S Haley, David J Porteous, Ian J Deary, Daniel J Smith, Barbara I Nicholl, David A Hinds, Amy V Jones, Serena Scollen, Weihua Meng, Blair H Smith, Lynne J Hocking
Publikováno v:
PLoS Medicine, Vol 13, Iss 8, p e1002090 (2016)
BackgroundChronic pain is highly prevalent and a significant source of disability, yet its genetic and environmental risk factors are poorly understood. Its relationship with major depressive disorder (MDD) is of particular importance. We sought to t
Externí odkaz:
https://doaj.org/article/8f71b918dc974bb39e192772bb999d22
Autor:
Ana Maria Fernandez-Pujals, Mark James Adams, Pippa Thomson, Andrew G McKechanie, Douglas H R Blackwood, Blair H Smith, Anna F Dominiczak, Andrew D Morris, Keith Matthews, Archie Campbell, Pamela Linksted, Chris S Haley, Ian J Deary, David J Porteous, Donald J MacIntyre, Andrew M McIntosh
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0142197 (2015)
The heritability of Major Depressive Disorder (MDD) has been estimated at 37% based largely on twin studies that rely on contested assumptions. More recently, the heritability of MDD has been estimated on large populations from registries such as the
Externí odkaz:
https://doaj.org/article/231fc94e3d754157952a1d01965c9c29
Autor:
Lynsey S. Hall, Mark J. Adams, Aleix Arnau-Soler, Toni-Kim Clarke, David M. Howard, Yanni Zeng, Gail Davies, Saskia P. Hagenaars, Ana Maria Fernandez-Pujals, Jude Gibson, Eleanor M. Wigmore, Thibaud S. Boutin, Caroline Hayward, Generation Scotland, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, David J. Porteous, Ian J. Deary, Pippa A. Thomson, Chris S. Haley, Andrew M. McIntosh
Publikováno v:
Translational Psychiatry, Vol 8, Iss 1, Pp 1-12 (2018)
Few replicable genetic associations for Major Depressive Disorder (MDD) have been identified. Recent studies of MDD have identified common risk variants by using a broader phenotype definition in very large samples, or by reducing phenotypic and ance
Autor:
Toni-Kim Clarke, Saskia P. Hagenaars, Ian J. Deary, Gail Davies, John M. Starr, Lynsey S. Hall, Sarah E. Harris, Michelle Luciano, Andrew M. McIntosh, Caroline Hayward, David J. Porteous, Generation Scotland, Ana Maria Fernandez-Pujals
Publikováno v:
International Journal of Epidemiology
Hagenaars, S P, Harris, S E, Clarke, T-K, Hall, L, Luciano, M, Fernandez-Pujals, A M, Davies, G, Hayward, C, Starr, J M, Porteous, D J & McIntosh, A M & Deary, I J 2016, ' Polygenic risk for coronary artery disease is associated with cognitive ability in older adults ', International Journal of Epidemiology, vol. 45, no. 2, pp. 433-440 . https://doi.org/10.1093/ije/dyv354
Hagenaars, S P, Harris, S E, Clarke, T-K, Hall, L, Luciano, M, Fernandez-Pujals, A M, Davies, G, Hayward, C, Starr, J M, Porteous, D J & McIntosh, A M & Deary, I J 2016, ' Polygenic risk for coronary artery disease is associated with cognitive ability in older adults ', International Journal of Epidemiology, vol. 45, no. 2, pp. 433-440 . https://doi.org/10.1093/ije/dyv354
BACKGROUND: Coronary artery disease (CAD) is associated with cognitive decrements and risk of later dementia, but it is not known if shared genetic factors underlie this association. We tested whether polygenic risk for CAD was associated with cognit
Autor:
Lynsey S, Hall, Mark J, Adams, Aleix, Arnau-Soler, Toni-Kim, Clarke, David M, Howard, Yanni, Zeng, Gail, Davies, Saskia P, Hagenaars, Ana, Maria Fernandez-Pujals, Jude, Gibson, Eleanor M, Wigmore, Thibaud S, Boutin, Caroline, Hayward, Generation, Scotland, David J, Porteous, Ian J, Deary, Pippa A, Thomson, Chris S, Haley, Andrew M, McIntosh
Publikováno v:
Translational Psychiatry
Few replicable genetic associations for Major Depressive Disorder (MDD) have been identified. Recent studies of MDD have identified common risk variants by using a broader phenotype definition in very large samples, or by reducing phenotypic and ance
Autor:
Ian J. Deary, Yanni Zeng, Aleix Arnau-Soler, Andrew M. McIntosh, Lynsey S. Hall, Jude Gibson, Caroline Hayward, Generation Scotland, Mark Adams, David J. Porteous, Chris Haley, Ana Maria Fernandez-Pujals, Saskia P. Hagenaars, Thibaud Boutin, Eleanor M. Wigmore, Gail Davies, David M. Howard, Pippa A. Thomson, Toni-Kim Clarke
Few replicable genetic associations for Major Depressive Disorder (MDD) have been identified. However recent studies of depression have identified common risk variants by using either a broader phenotype definition in very large samples, or by reduci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::409d829087c8485de87446d0f9c6d2e7
https://doi.org/10.1101/130229
https://doi.org/10.1101/130229
Autor:
Archie Campbell, Ian J. Deary, David J. Porteous, Saskia P. Hagenaars, Caroline Hayward, Jonathan D. Hafferty, Lynsey S. Hall, Toni-Kim Clarke, Andrew M. McIntosh, Gail Davies, Jude Gibson, Stephen M. Lawrie, Ella Wigmore, Heather C. Whalley, Mark Adams, Ana Maria Fernandez-Pujals
Publikováno v:
Sibley, H, Adams, M, Hall, L S, Clarke, T-K, Fernandez-Pujals, A M, Gibson, J, Wigmore, E, Hafferty, J, Hagenaars, S, Davies, G, Campbell, A, Hayward, C, Lawrie, S, Porteous, D, Deary, I & McIntosh, A 2016, ' Dissection of Major Depressive Disorder using polygenic risk scores for Schizophrenia in two independent cohorts ', Translational Psychiatry, vol. 6, no. 11, pp. e938 . https://doi.org/10.1038/tp.2016.207
Major depressive disorder (MDD) is known for its substantial clinical and suspected causal heterogeneity. It is characterised by low mood, psychomotor slowing, and increased levels of the personality trait neuroticism; factors also associated with sc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1970bf3c14d2e72eafe594cfc8afa4a
https://hdl.handle.net/20.500.11820/3bf013d4-37e6-4c2f-b396-d9a9461784b2
https://hdl.handle.net/20.500.11820/3bf013d4-37e6-4c2f-b396-d9a9461784b2