Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Ana María López-Colomé"'
Publikováno v:
Cellular & Molecular Biology Letters, Vol 27, Iss 1, Pp 1-22 (2022)
Abstract Protease activated receptors (PARs) are among the first receptors shown to transactivate other receptors: noticeably, these interactions are not limited to members of the same family, but involve receptors as diverse as receptor kinases, pro
Externí odkaz:
https://doaj.org/article/36c4540b3f6d4159836014773a117b8c
Publikováno v:
Journal of Hematology & Oncology, Vol 10, Iss 1, Pp 1-15 (2017)
Abstract Paxilllin is a multifunctional and multidomain focal adhesion adapter protein which serves an important scaffolding role at focal adhesions by recruiting structural and signaling molecules involved in cell movement and migration, when phosph
Externí odkaz:
https://doaj.org/article/9913d85ee7224b87acf22255a08f8c93
Autor:
Alejandro Alvarez-Arce, Irene Lee-Rivera, Edith López, Arturo Hernández-Cruz, Ana María López-Colomé
Publikováno v:
International Journal of Cell Biology, Vol 2017 (2017)
The serine protease thrombin activates Protease-Activated Receptors (PARs), a family of G-protein-coupled receptors (GPCRs) activated by the proteolytic cleavage of their extracellular N-terminal domain. Four members of this family have been identifi
Externí odkaz:
https://doaj.org/article/f2e225ec9bc84c2cae94b63afbec9e86
Publikováno v:
TIP Revista Especializada en Ciencias Químico-Biológicas, Vol 8, Iss 2, Pp 71-81 (2005)
La función del glutamato en la retina, como neurotransmisor, factor trófico o neurotoxina, se relaciona directamente con la diversidad y la composición heteromérica de sus receptores. Los receptores de glutamato de tipo NMDA (NMDARs) son tetrá
Externí odkaz:
https://doaj.org/article/e4a5ca34e9254c8c913ced8f15bc1153
Publikováno v:
ASN Neuro, Vol 4 (2012)
Glu (glutamate), the excitatory transmitter at the main signalling pathway in the retina, is critically involved in changes in the protein repertoire through the activation of signalling cascades, which regulate protein synthesis at transcriptional a
Externí odkaz:
https://doaj.org/article/bbbe4900131c45ffaf58563fba4fba95
Publikováno v:
TIP Revista Especializada en Ciencias Químico-Biológicas. 25
La fosfatasa de tirosina PTP-PEST, también llamada PTPN12, es una proteína que se expresa de forma ubicua, y se regula por fosforilación en los residuos de serina y treonina. El gen PTPN12, en humanos, se localiza en el cromosoma 7q11.23. La prote
Publikováno v:
Cellular signalling. 75
PAR1 activation by thrombin promotes intracellular signaling leading to RPE cell transformation, proliferation, and migration, characteristic of fibroproliferative eye diseases. Due to the cleavage of PAR1 N-terminal domain, carried by thrombin, the
Publikováno v:
Journal of Hematology & Oncology, Vol 10, Iss 1, Pp 1-15 (2017)
Journal of Hematology & Oncology
Journal of Hematology & Oncology
Paxilllin is a multifunctional and multidomain focal adhesion adapter protein which serves an important scaffolding role at focal adhesions by recruiting structural and signaling molecules involved in cell movement and migration, when phosphorylated
Publikováno v:
Life Sciences. 265:118860
Aims The retinal pigment epithelium (RPE) is a highly specialized cell monolayer, that plays a key role in the maintenance of photoreceptor function and the blood-retina barrier (BRB). In this study, we found that a myristoylated pseudosubstrate of P
Autor:
Alejandro Alvarez-Arce, Ana María López-Colomé, E.D. Aguilar-Solis, Edith López, Irene Lee-Rivera
Publikováno v:
Cellular signalling. 36
The migration of retinal pigment epithelial (RPE) cells is an important step in various pathologic conditions including subretinal neovascularization (SRN), proliferative vitreoretinopathy (PVR) and, importantly, as a consequence of retinal surgery.