Effects of imipramine on cancer patients over-expressing Fascin1; description of the HITCLIF clinical trial

Autor: Antonio Asensi-Cantó, Edith Rodríguez-Braun, Asunción Beltrán-Videla, Ana María Hurtado, Pablo Conesa-Zamora

Publikováno v: Frontiers in Oncology, Vol 13 (2023)

BackgroundTumor invasion and metastasis are responsible for the majority of cancer-related deaths. The identification of molecules involved in these processes is crucial to design effective treatments that can halt the progression of cancer. To sprea

Externí odkaz: https://doaj.org/article/e2e9a84e5e264fed9ebd481f1e51f5b5

Cancer testis antigens in myelodysplastic syndromes revisited: a targeted RNA-seq approach

Autor: Ana María Hurtado López, Tzu Hua Chen-Liang, María Zurdo, Salvador Carrillo-Tornel, Joaquín Panadero, Eduardo José Salido, Victor Beltrán, Begoña Muiña, MariLuz Amigo, Noelia Navarro-Villamor, Rosa Cifuentes, Inés Calabria, Ana Isabel Antón, Raúl Teruel, Manuel Muro, Vicente Vicente, Andrés Jerez

Publikováno v: OncoImmunology, Vol 9, Iss 1 (2020)

Cancer-Testis antigens (CTA) are named after the tissues where they are mainly expressed: in germinal and in cancer cells, a process that mimics many gametogenesis features. Mapping accurately the CTA gene expression signature in myelodysplastic synd

Externí odkaz: https://doaj.org/article/bf897c740d3443aba1c3d17ecf6f3e99

NOTCH1 mutation in chronic lymphocytic leukaemia is associated with an enhanced cell cycle G1 /S transition and specific cyclin overexpression: Preclinical ground for targeted inhibition

Autor: Salvador Carrillo‐Tornel, Tzu Hua Chen‐Liang, María Zurdo, Anna Puiggros, Andrea Gómez‐Llonín, María Dolores García‐Malo, Ernesto José Cuenca‐Zamora, Francisco José Ortuño, Ana María Hurtado López, Blanca Espinet, Andrés Jerez

Publikováno v: British Journal of Haematology. 201:470-479

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::80682e957f3abe59f5c384249f0e724c
https://doi.org/10.1111/bjh.18609

NOTCH1 mutation in chronic lymphocytic leukaemia is associated with an enhanced cell cycle G1/S transition and specific cyclin overexpression: Preclinical ground for targeted inhibition.

Autor: Carrillo‐Tornel, Salvador, Chen‐Liang, Tzu Hua, Zurdo, María, Puiggros, Anna, Gómez‐Llonín, Andrea, García‐Malo, María Dolores, Cuenca‐Zamora, Ernesto José, Ortuño, Francisco José, López, Ana María Hurtado, Espinet, Blanca, Jerez, Andrés

Publikováno v: British Journal of Haematology; May2023, Vol. 201 Issue 3, p470-479, 10p

Somatic mTOR mutation in clonally expanded T lymphocytes associated with chronic graft versus host disease

Autor: Ana María Hurtado, Satu Mustjoki, Urpu Salmenniemi, Jani Huuhtanen, Pekka Ellonen, Rajiv K. Khajuria, Mikko Myllymäki, Matti Kankainen, Daehong Kim, Sofie Lundgren, Mikko A. I. Keränen, Giljun Park, Maija Itälä-Remes, Tzu Hua Chen-Liang, Andres Jerez, Samuli Eldfors, Laura Cardeñoso, Sari Hannula, Oscar Brück, Anna Kreutzman, Valle Gómez García de Soria, Tapio Lönnberg, Cecilia Muñoz-Calleja

Publikováno v: Biblos-e Archivo: Repositorio Institucional de la UAM
Universidad Autónoma de Madrid
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Nature Communications
Biblos-e Archivo. Repositorio Institucional de la UAM
instname

Graft versus host disease (GvHD) is the main complication of allogeneic hematopoietic stem cell transplantation (HSCT). Here we report studies of a patient with chronic GvHD (cGvHD) carrying persistent CD4 T cell clonal expansion harboring somatic mT

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80004dc6bc4cf39c734b43d69bf77021
https://doi.org/10.1038/s41467-020-16115-w