Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Ana M. Romão"'
Autor:
Oliver A. Stone, Mohamed El-Brolosy, Kerstin Wilhelm, Xiaojing Liu, Ana M. Romão, Elisabetta Grillo, Jason K. H. Lai, Stefan Günther, Sylvia Jeratsch, Carsten Kuenne, I-Ching Lee, Thomas Braun, Massimo M. Santoro, Jason W. Locasale, Michael Potente, Didier Y. R. Stainier
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
The glycolytic enzyme pyruvate kinase M2 (PKM2) is required for nucleotide synthesis and cell proliferation. Using gene expression and metabolomics analyses, the authors here show that PKM2 regulates methionine metabolism and DNA methylation in endot
Externí odkaz:
https://doaj.org/article/193983107e6a406b9727e989c6776bf0
Publikováno v:
Journal of Pharmacy and Bioallied Sciences, Vol 3, Iss 3, Pp 350-360 (2011)
The long history of Cannabis sativa had its development stimulated and oriented for medicine after the discovery and chemical characterization of its main active ingredient, the 9-tetrahydrocannabinol (9-THC). Consequently, a binding site for 9-THC w
Externí odkaz:
https://doaj.org/article/da455bf16ebb4cb3b41728b3d0b78d52
Autor:
Sylvia Jeratsch, Carsten Kuenne, Ana M Romão, Oliver A. Stone, Kerstin Wilhelm, Didier Y.R. Stainier, Massimo M. Santoro, Mohamed A. El-Brolosy, Thomas Braun, Stefan Günther, Jason W. Locasale, Michael Potente, Xiaojing Liu, Elisabetta Grillo, I-Ching Lee, Jason Kuan Han Lai
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Nature Communications
Nature Communications
Despite their inherent proximity to circulating oxygen and nutrients, endothelial cells (ECs) oxidize only a minor fraction of glucose in mitochondria, a metabolic specialization that is poorly understood. Here we show that the glycolytic enzyme pyru
Autor:
Hermann Bihler, Carlos M. Farinha, Martin Mense, Zhiwei Cai, Jia Liu, Nikhil T. Awatade, Y. Cheng, Margarida D. Amaral, Dayna Mercadante, Ana M Romão, Isaac Musisi, Yiting Wang, David N. Sheppard, Walailak Jantarajit
Publikováno v:
British Journal of Pharmacology. 175:1017-1038
Background and purpose Rescue of F508del-cystic fibrosis (CF) transmembrane conductance regulator (CFTR), the most common CF mutation, requires small molecules that overcome protein processing, stability and channel gating defects. Here, we investiga
Autor:
Jia, Liu, Hermann, Bihler, Carlos M, Farinha, Nikhil T, Awatade, Ana M, Romão, Dayna, Mercadante, Yi, Cheng, Isaac, Musisi, Walailak, Jantarajit, Yiting, Wang, Zhiwei, Cai, Margarida D, Amaral, Martin, Mense, David N, Sheppard
Publikováno v:
British journal of pharmacology. 175(7)
BACKGROUND AND PURPOSE: Rescue of F508del‐cystic fibrosis (CF) transmembrane conductance regulator (CFTR), the most common CF mutation, requires small molecules that overcome protein processing, stability and channel gating defects. Here, we invest
Autor:
José, Sereno, Ana M, Romão, Belmiro, Parada, Patrícia, Lopes, Eugénia, Carvalho, Frederico, Teixeira, Flávio, Reis
Publikováno v:
Journal of Pharmacology & Pharmacotherapeutics
Objective: To compare the cardiorenal effects of early versus late cyclosporine (CsA) to sirolimus (SRL) conversion, using a novel animal model that mimics these protocols used in the clinical practice, and focusing on blood pressure, heart rate (HR)