Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Ana M. Muñoz-Cabello"'
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Neurogenesis in developing and adult mammalian brain is a tightly regulated process that relies on neural stem cell (NSC) activity. There is increasing evidence that mitochondrial metabolism affects NSC homeostasis and differentiation but the precise
Externí odkaz:
https://doaj.org/article/2334743a2ac0492bb5389c0185eea69c
Autor:
Javier Villadiego, Juan García-Arriaza, Reposo Ramírez-Lorca, Roberto García-Swinburn, Daniel Cabello-Rivera, Alicia E. Rosales-Nieves, María I. Álvarez-Vergara, Fernando Cala-Fernández, Ernesto García-Roldán, Juan L. López-Ogáyar, Carmen Zamora, David Astorgano, Guillermo Albericio, Patricia Pérez, Ana M. Muñoz-Cabello, Alberto Pascual, Mariano Esteban, José López-Barneo, Juan José Toledo-Aral
Vaccines against SARS-CoV-2 have been shown to be safe and effective but their protective efficacy against infection in the brain is yet unclear. Here, in the susceptible transgenic K18-hACE2 mouse model of severe coronavirus disease 2019 (COVID-19),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::518f7ac419ae0636300399fe703601d3
http://hdl.handle.net/10261/286599
http://hdl.handle.net/10261/286599
Autor:
Daniel Cabello-Rivera, Patricia Ortega-Sáenz, Lin Gao, Ana M. Muñoz-Cabello, Victoria Bonilla-Henao, Paul T. Schumacker, José López-Barneo
Acute oxygen (O2) sensing is essential for adaptation of organisms to hypoxic environments or medical conditions with restricted exchange of gases in the lung. The main acute O2-sensing organ is the carotid body (CB), which contains neurosecretory ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adec3a9f23e8cfce2780630adf412507
http://hdl.handle.net/10261/307112
http://hdl.handle.net/10261/307112
Autor:
David Scott, Teresa Cassel, Gang Xin, Lingling Liu, Benjamin Sunkel, Siwen Kang, José López-Barneo, Ruoning Wang, Meng Wang, Jun J. Yang, Andrew N. Lane, Xuyong Chen, Ana M. Muñoz-Cabello, Tingting Wang, Teresa W.-M. Fan, Benjamin Z. Stanton, JN Rashida Gnanaprakasam
Publikováno v:
Sci Immunol
Effective T cell-mediated immune responses require the proper allocation of metabolic resources to sustain growth, proliferation, and cytokine production. Epigenetic control of the genome also governs T cell transcriptome and T cell lineage commitmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19502c0f92076d2e09791318e4967018
https://api.elsevier.com/content/abstract/scopus_id/85129198797
https://api.elsevier.com/content/abstract/scopus_id/85129198797
Autor:
Javier Villadiego, Juan García-Arriaza, Reposo Ramírez-Lorca, Daniel Cabello-Rivera, María I. Álvarez-Vergara, Fernando Cala-Fernández, Roberto García-Swinburn, Ernesto García-Roldán, Juan L. López-Ogáyar, Carmen Zamora, David Astorgano, Patricia Pérez, Alicia Rosales-Nieves, Ana M. Muñoz-Cabello, Alberto Pascual, Mariano Esteban, Jose Lopez-Barneo, Juan Toledo-Aral
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
The protective efficacy of vaccines against SARS-CoV-2 infection in the brain is yet unclear. Here, in the susceptible transgenic K18-hACE2 mouse model of severe COVID-19 disease, we report a detailed spatiotemporal description of the SARS-CoV-2 infe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::405c5e5c5f73d4a095908f11fd69413f
http://hdl.handle.net/10261/269257
http://hdl.handle.net/10261/269257
Publikováno v:
PLoS Genetics, Vol 14, Iss 6, p e1007407 (2018)
idUS. Depósito de Investigación de la Universidad de Sevilla
instname
Digital.CSIC. Repositorio Institucional del CSIC
PLoS Genetics
idUS. Depósito de Investigación de la Universidad de Sevilla
instname
Digital.CSIC. Repositorio Institucional del CSIC
PLoS Genetics
Upon telomerase inactivation, telomeres gradually shorten with each cell division until cells enter replicative senescence. In Saccharomyces cerevisiae, the kinases Mec1/ATR and Tel1/ATM protect the genome during pre-senescence by preventing telomere
Autor:
José López-Barneo, Patricia Ortega-Sáenz, Ignacio Arias-Mayenco, Hortensia Torres-Torrelo, Ana M. Muñoz-Cabello
Publikováno v:
Methods in Molecular Biology ISBN: 9781493976645
The carotid body is the main arterial chemoreceptor in mammals that mediates the cardiorespiratory reflexes activated by acute hypoxia. Here we describe the protocols followed in our laboratory to study responsiveness to hypoxia of single, enzymatica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::171fbebc099c09d3e3d7ea855e8d3b9a
https://doi.org/10.1007/978-1-4939-7665-2_12
https://doi.org/10.1007/978-1-4939-7665-2_12
Autor:
Robert E. London, Felipe Cortés-Ledesma, R. Scott Williams, Ana M. Muñoz-Cabello, Jenna Ariel Lieberman, Logan R. Butler, Andrés Herrero-Ruiz, Geoffrey A. Mueller, Jason Williams, Matthew J. Schellenberg
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Science
instname
Science
Schellenberg, Matthew J. et al.
Topoisomerase 2 (TOP2) DNA transactions proceed via formation of the TOP2 cleavage complex (TOP2cc), a covalent enzyme-DNA reaction intermediate that is vulnerable to trapping by potent anticancer TOP2 drugs. How
Topoisomerase 2 (TOP2) DNA transactions proceed via formation of the TOP2 cleavage complex (TOP2cc), a covalent enzyme-DNA reaction intermediate that is vulnerable to trapping by potent anticancer TOP2 drugs. How
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06e44a0e335eb8c99d8e05d324c2f4ed
http://hdl.handle.net/10261/165405
http://hdl.handle.net/10261/165405
Autor:
Michiel Vermeulen, Thomas L. Carroll, Gordon Peters, Ana O'Loghlen, Tomas Racek, Ana M. Muñoz-Cabello, Fabrice Lavial, Emily Bernstein, Véronique Azuara, Ambrosius P. Snijders, Natalia Kunowska, Alexandre Gaspar-Maia, Helen Pemberton, Johannes Graumann, Ana Banito, Jesús Gil, Niall Dillon, Patrizia Beolchi, Hsan-au Wu, Edith Heard, Osamu Masui
Publikováno v:
Cell Stem Cell
Summary The Polycomb Group (PcG) of chromatin modifiers regulates pluripotency and differentiation. Mammalian genomes encode multiple homologs of the Polycomb repressive complex 1 (PRC1) components, including five orthologs of the Drosophila Polycomb
Autor:
Macarena Guijo, Félix Prado, Silvia Jimeno-González, Laura Payán-Bravo, Gabriel Gutiérrez, José C. Reyes, Ana M. Muñoz-Cabello
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
RNA polymerase II (RNAPII) transcription elongation is a highly regulated process that greatly influences mRNA levels as well as pre-mRNA splicing. Despite many studies in vitro, how chromatin modulates RNAPII elongation in vivo is still unclear. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c1f413c4dbf04fd583ba9f6a358d29f
http://hdl.handle.net/10261/270670
http://hdl.handle.net/10261/270670