Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Ana M. Lucas-Osma"'
Autor:
Krishnapriya Hari, Ana M. Lucas-Osma, Krista Metz, Shihao Lin, Noah Pardell, David A. Roszko, Sophie Black, Anna Minarik, Rahul Singla, Marilee J. Stephens, Robert A. Pearce, Karim Fouad, Kelvin E. Jones, Monica A. Gorassini, Keith K. Fenrich, Yaqing Li, David J. Bennett
Publikováno v:
Nat Neurosci
Movement and posture depend on sensory feedback that is regulated by specialized GABAergic neurons (GAD2+) that form axo-axonic contacts onto myelinated proprioceptive sensory axons and are thought to be inhibitory. However, we report here that activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acccccd9fa44e4cfea1318d543bd331d
https://doi.org/10.1038/s41593-022-01162-x
https://doi.org/10.1038/s41593-022-01162-x
Autor:
Shihao Lin, Krishnapriya Hari, Ana M. Lucas-Osma, Sophie Black, Aysan Khatmi, Karim Fouad, Monica A. Gorassini, Yaqing Li, Keith K. Fenrich, David J. Bennett
When a muscle is stretched it not only responds with a reflex, but the sensory afferent feedback also depolarizes many afferents throughout the spinal cord (termed primary afferent depolarization, PAD), readying the whole limb for further disturbance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f996ab5fe4e275d567eb843c73fb0141
https://doi.org/10.1101/2022.07.04.498712
https://doi.org/10.1101/2022.07.04.498712
Autor:
Ana M. Lucas-Osma, Yaqing Li, Marilee J. Stephens, Sophie Black, Andrew H. Ahn, Keith K. Fenrich, Katie Murray, David J. Bennett, Karim Fouad, Charles J. Heckman, Shihao Lin
Publikováno v:
J Neurophysiol
The monosynaptic stretch reflex (MSR) plays an important role in feedback control of movement and posture but can also lead to unstable oscillations associated with tremor and clonus, especially when increased with spinal cord injury (SCI). To contro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba857c64361b90b157a22303e21c0d1b
https://doi.org/10.1152/jn.00805.2018
https://doi.org/10.1152/jn.00805.2018
Autor:
Ana M. Lucas-Osma, Rahul Singla, David J. Bennett, Sophie Black, Yaqing Li, Keith K. Fenrich, Shihao Lin, Karim Fouad
Publikováno v:
Journal of Neurophysiology. 120:2953-2974
Activation of GABAA receptors on sensory axons produces a primary afferent depolarization (PAD) that modulates sensory transmission in the spinal cord. While axoaxonic synaptic contacts of GABAergic interneurons onto afferent terminals have been exte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e4d6f9c102a2f91abe8881d39cb4ac2
https://doi.org/10.1152/jn.00499.2018
https://doi.org/10.1152/jn.00499.2018
Autor:
Ana M, Lucas-Osma, Emma K A, Schmidt, Romana, Vavrek, David J, Bennett, Karim, Fouad, Keith K, Fenrich
Publikováno v:
Behavioural Brain Research. 422:113731
Animal models of cervical spinal cord injury (SCI) have frequently utilized partial transection injuries to evaluate plasticity promoting treatments such as rehabilitation training of skilled reaching and grasping tasks. Though highly useful for stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::317c2c6c443a31f861bf267f6afb175c
https://doi.org/10.1016/j.bbr.2021.113731
https://doi.org/10.1016/j.bbr.2021.113731
Autor:
Ingela Hammar, Yaqing Li, Krishnapriya Hari, David J. Bennett, Ana M. Lucas-Osma, Keith K. Fenrich, Elzbieta Jankowska
Publikováno v:
J Neurophysiol
The aim of the study was to examine whether the sustained increases in the excitability of afferent fibers traversing the dorsal columns evoked by their polarization depend on the branching points of these fibers. To this end, the effects of epidural
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52981105c9a78b9375ceba5a1ed2c5fe
https://europepmc.org/articles/PMC7474458/
https://europepmc.org/articles/PMC7474458/
Autor:
Pamela J. F. Raposo, Romana Vavrek, David J. Bennett, Karim Fouad, Aleksandra Krajacic, Ana M. Lucas-Osma, Emma K. A. Schmidt, Juan Forero, Phillip G. Popovich, Abel Torres-Espín, Keith K. Fenrich
Publikováno v:
Brain. 141:1946-1962
Rehabilitative training is one of the most successful therapies to promote motor recovery after spinal cord injury, especially when applied early after injury. Polytrauma and management of other medical complications in the acute post-injury setting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b07bb0e96b2c92f92ccbdf96aeebbe8c
https://doi.org/10.1093/brain/awy128
https://doi.org/10.1093/brain/awy128
Autor:
Marilee J. Stephens, Leo Sanelli, Keith K. Fenrich, Mischa V Bandet, Ana M. Lucas-Osma, Yaqing Li, Romana Vavrek, Antonio Fabio Di Narzo, Ian R. Winship, Sophie Black, Stella Dracheva, David J. Bennett, Karim Fouad
Publikováno v:
Nature medicine
Blood vessels in the central nervous system (CNS) are controlled by neuronal activity. For example, widespread vessel constriction (vessel tone) is induced by brainstem neurons that release the monoamines serotonin and noradrenaline, and local vessel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e94670c080217a9922e751723c57d0f
https://doi.org/10.1038/nm.4331
https://doi.org/10.1038/nm.4331
Autor:
Karim Fouad, Ana M. Lucas-Osma, Krishnapriya Hari, Shihao Lin, Keith K. Fenrich, Yaqing Li, David J. Bennett
Publikováno v:
The FASEB Journal. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::587a103d27a102d8e7420a0e06ef2a6d
https://doi.org/10.1096/fasebj.2019.33.1_supplement.849.2
https://doi.org/10.1096/fasebj.2019.33.1_supplement.849.2
Autor:
Rahul Singla, Ana M. Lucas-Osma, Yaqing Li, Krishnapriya Hari, David J. Bennett, Marilee J. Stephens, Keith K. Fenrich, Charles J. Heckman, Karim Fouad, Ying Zhang, Shihao Lin
Publikováno v:
Journal of neurophysiology. 121(4)
Spinal cord injury leads to a devastating loss of motor function and yet is accompanied by a paradoxical emergence of muscle spasms, which often involve complex muscle activation patterns across multiple joints, reciprocal muscle timing, and rhythmic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59307eaafa9db9e5859966eb10cd45ad
https://pubmed.ncbi.nlm.nih.gov/30625014
https://pubmed.ncbi.nlm.nih.gov/30625014