Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Ana M. Blasini"'
Publikováno v:
Clinical Immunology. 142:243-251
Systemic lupus erythematosus (SLE) is characterized by abnormal signal transduction mechanisms in T lymphocytes. Linker for activation of T cells (LAT) couples TCR/CD3 activation with downstream signaling pathways. We reported diminished ERK 1/2 kina
Autor:
Martin A. Rodriguez, Ana M. Blasini
Publikováno v:
International Reviews of Immunology. 23:265-272
Some of the signaling phenotypic abnormalities observed in peripheral blood T cells from patients with systemic lupus erythematosus resemble those seen in cells anergized by stimulation through the TCR/CD3 complex, in the absence of costimulatory sig
Autor:
Samandhy Cedeño, Guillermina Alonso, Magdalena Paris, Ana M. Blasini, Martin A. Rodriguez, Domenico F Cifarelli, Fabiola Placeres
Publikováno v:
Clinical Immunology. 106:41-49
The integrity of the Ras/Raf/mitogen-activated protein kinase (MAPK) cascade is critical for maintenance of T cell tolerance, a process that fails in patients with systemic lupus erythematosus (SLE). In this study we have examined the activity of mit
Autor:
Salazar S, I L Stekman, Magdalena Paris, Brundula, Rivas Lj, Ana M. Blasini, Martin A. Rodriguez
Publikováno v:
Arthritis & Rheumatism. 42:1908-1916
Objective. To examine the expression of molecules known to participate in early T cell receptor (TCR)/CD3 signaling in peripheral blood (PB) T lymphocytes from patients with systemic lupus erythematosus (SLE). Methods. Signaling molecules were analyz
Autor:
Veronika Brundula, Ana M. Blasini, Martin A. Rodriguez, Liliana Rivas, Susana Salazar, I L Stekman, Magdalena Paris
Publikováno v:
Journal of Autoimmunity. 11:387-393
We have recently observed an abnormal pattern of protein tyrosine phosphoryl-ation in resting T lymphocytes obtained from peripheral blood of patients with systemic lupus erythematosus (SLE). To examine whether these findings may be related to dysreg
Publikováno v:
Clinical Immunology and Immunopathology. 70:66-72
In the present study we have examined the potential contribution of IL-2/IL-2R interactions in CD3-mediated responses by T lymphocytes from patients with systemic lupus erythematosus (SLE). T-cells from SLE patients showed normal IL-2 production when
Publikováno v:
International Archives of Allergy and Immunology. 101:234-239
An ELISA-type assay useful for the evaluation of the complement activity in serum is described. Aggregated pooled human IgG (IgGn) prepared so as to exclude large and small aggregates, to resemble soluble circulating immune complexes, was used to coa
Autor:
Ana M. Blasini, Martin A. Rodriguez
Publikováno v:
Molecular Autoimmunity ISBN: 0387245332
The homeostasis of adaptive immune responses is determined by the integrity of postreceptor signaling in its two main cellular components: T and B cells. The last 2 decades have brought up mounting information on the different intracellular routes tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a315d9fbc1b93a1e04973a59ef195119
https://doi.org/10.1007/0-387-24534-0_18
https://doi.org/10.1007/0-387-24534-0_18
Autor:
Williams Rc, Martin A. Rodriguez, Delgado Mb, Guevara P, Ana M. Blasini, Ramirez Jl, Valdivieso C, I L Stekman
Publikováno v:
Lupus. 5:300-302
Previous studies suggest a potential association between human immunoglobulin (Ig) genes and susceptibility to systemic lupus erythematosus (SLE). Ig allotypic determinants seem to confer an increased risk for the disease in various ethnic patient po
Autor:
Ana M, Blasini, Martín A, Rodríguez
Publikováno v:
International reviews of immunology. 23(3-4)
Some of the signaling phenotypic abnormalities observed in peripheral blood T cells from patients with systemic lupus erythematosus resemble those seen in cells anergized by stimulation through the TCR/CD3 complex, in the absence of costimulatory sig